Detailed information NTG1018718

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: DQL04_RS08880
• Genome accession: NZ_LS483340
• Coordinates: 1752084..1752851 (-)
• Length: 255 a.a.
• NCBI ID: WP_003058809.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC12062
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1747084..1757851

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL04_RS08870 (NCTC12062_01758)	-	1749014..1750159 (-)	1146	WP_111690858.1	tyrosine-type recombinase/integrase	-
DQL04_RS08875 (NCTC12062_01759)	dinD	1750417..1751271 (-)	855	WP_047236050.1	DNA damage-inducible protein D	-
DQL04_RS09390 (NCTC12062_01760)	-	1751532..1751693 (-)	162	WP_168681587.1	hypothetical protein	-
DQL04_RS08880 (NCTC12062_01761)	irvR	1752084..1752851 (-)	768	WP_003058809.1	helix-turn-helix transcriptional regulator	Regulator
DQL04_RS08885 (NCTC12062_01762)	-	1753005..1753211 (+)	207	WP_002992503.1	helix-turn-helix transcriptional regulator	-
DQL04_RS08890 (NCTC12062_01763)	-	1753245..1754012 (+)	768	WP_080343567.1	Bro-N domain-containing protein	-
DQL04_RS08895 (NCTC12062_01764)	-	1754022..1754639 (+)	618	WP_047236051.1	Bro-N domain-containing protein	-
DQL04_RS08900 (NCTC12062_01765)	-	1754666..1754908 (+)	243	WP_000648623.1	hypothetical protein	-
DQL04_RS08905 (NCTC12062_01766)	-	1755165..1755497 (+)	333	WP_002992497.1	hypothetical protein	-
DQL04_RS08910 (NCTC12062_01767)	-	1755497..1755688 (+)	192	WP_080032246.1	hypothetical protein	-
DQL04_RS08915 (NCTC12062_01768)	-	1755700..1756062 (+)	363	WP_047236052.1	hypothetical protein	-
DQL04_RS08920 (NCTC12062_01769)	-	1756059..1756367 (+)	309	WP_047236053.1	hypothetical protein	-
DQL04_RS08925 (NCTC12062_01770)	-	1756370..1756642 (+)	273	WP_047236054.1	hypothetical protein	-
DQL04_RS08930 (NCTC12062_01771)	-	1756643..1757509 (+)	867	WP_047236055.1	primase alpha helix C-terminal domain-containing protein	-

Sequence

Protein

• Length: 255 a.a.
• Molecular weight: 28725.00 Da
• Isoelectric Point: 4.3544

>NTDB_id=1018718 DQL04_RS08880 WP_003058809.1 1752084..1752851(-) (irvR) [Streptococcus pyogenes strain NCTC12062]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide

• Length: 768 bp

>NTDB_id=1018718 DQL04_RS08880 WP_003058809.1 1752084..1752851(-) (irvR) [Streptococcus pyogenes strain NCTC12062]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAATTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCATTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (23-68)

• Peptidase S24-like (Peptidase_S24) (141-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	34	100	0.4