Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   DQM35_RS05320 Genome accession   NZ_LS483338
Coordinates   1021124..1021600 (-) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain NCTC12064     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1016124..1026600
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM35_RS05305 (NCTC12064_01049) fbp54 1016937..1018589 (+) 1653 WP_002991968.1 Rqc2 family fibronectin-binding protein Fbp54 -
  DQM35_RS05310 (NCTC12064_01050) - 1018648..1019895 (-) 1248 WP_002991966.1 tetratricopeptide repeat protein -
  DQM35_RS05315 (NCTC12064_01051) - 1019885..1021066 (-) 1182 WP_002990002.1 AI-2E family transporter -
  DQM35_RS05320 (NCTC12064_01052) mutX 1021124..1021600 (-) 477 WP_002984880.1 8-oxo-dGTP diphosphatase Machinery gene
  DQM35_RS05325 (NCTC12064_01053) rfbB 1021821..1022861 (-) 1041 WP_014635423.1 dTDP-glucose 4,6-dehydratase -
  DQM35_RS05330 (NCTC12064_01054) - 1023105..1023698 (-) 594 WP_002990099.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  DQM35_RS05335 (NCTC12064_01055) rfbA 1023698..1024567 (-) 870 WP_014407521.1 glucose-1-phosphate thymidylyltransferase RfbA -
  DQM35_RS05340 (NCTC12064_01056) - 1024625..1025731 (-) 1107 WP_020833434.1 FAD-binding oxidoreductase -
  DQM35_RS05345 (NCTC12064_01057) - 1025771..1026559 (-) 789 WP_002984887.1 Nif3-like dinuclear metal center hexameric protein -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=1018481 DQM35_RS05320 WP_002984880.1 1021124..1021600(-) (mutX) [Streptococcus pyogenes strain NCTC12064]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=1018481 DQM35_RS05320 WP_002984880.1 1021124..1021600(-) (mutX) [Streptococcus pyogenes strain NCTC12064]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCCGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703