Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   DQL03_RS04075 Genome accession   NZ_LS483337
Coordinates   777066..777542 (+) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain NCTC12047     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 772066..782542
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL03_RS04050 (NCTC12047_00801) - 772107..772895 (+) 789 WP_111674895.1 Nif3-like dinuclear metal center hexameric protein -
  DQL03_RS04055 (NCTC12047_00802) - 772935..774041 (+) 1107 WP_111674896.1 NAD(P)/FAD-dependent oxidoreductase -
  DQL03_RS04060 (NCTC12047_00803) rfbA 774099..774968 (+) 870 WP_014407521.1 glucose-1-phosphate thymidylyltransferase RfbA -
  DQL03_RS04065 (NCTC12047_00804) - 774968..775561 (+) 594 WP_002990099.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  DQL03_RS04070 (NCTC12047_00805) rfbB 775805..776845 (+) 1041 WP_023612000.1 dTDP-glucose 4,6-dehydratase -
  DQL03_RS04075 (NCTC12047_00806) mutX 777066..777542 (+) 477 WP_002984880.1 NUDIX hydrolase Machinery gene
  DQL03_RS04080 (NCTC12047_00807) - 777600..778781 (+) 1182 WP_002984879.1 AI-2E family transporter -
  DQL03_RS04085 (NCTC12047_00808) - 778771..780018 (+) 1248 WP_063629099.1 tetratricopeptide repeat protein -
  DQL03_RS04090 (NCTC12047_00809) fbp54 780077..781729 (-) 1653 WP_111674897.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=1018367 DQL03_RS04075 WP_002984880.1 777066..777542(+) (mutX) [Streptococcus pyogenes strain NCTC12047]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=1018367 DQL03_RS04075 WP_002984880.1 777066..777542(+) (mutX) [Streptococcus pyogenes strain NCTC12047]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCCGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703