Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   DQL28_RS03280 Genome accession   NZ_LS483334
Coordinates   633049..633711 (+) Length   220 a.a.
NCBI ID   WP_030126965.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC12050     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 628049..638711
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL28_RS03260 (NCTC12050_00635) - 628923..630923 (+) 2001 WP_030126966.1 potassium transporter Kup -
  DQL28_RS03265 (NCTC12050_00636) - 630947..631225 (-) 279 WP_002989164.1 GIY-YIG nuclease family protein -
  DQL28_RS03270 (NCTC12050_00637) - 631215..631991 (-) 777 WP_002994360.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  DQL28_RS03275 (NCTC12050_00638) - 632109..632849 (+) 741 WP_011054661.1 lysophospholipid acyltransferase family protein -
  DQL28_RS03280 (NCTC12050_00639) comEA/celA/cilE 633049..633711 (+) 663 WP_030126965.1 ComEA family DNA-binding protein Machinery gene
  DQL28_RS03285 (NCTC12050_00640) comEC/celB 633692..635935 (+) 2244 WP_030126964.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DQL28_RS03290 (NCTC12050_00641) holA 636006..637046 (+) 1041 WP_030126963.1 DNA polymerase III subunit delta -
  DQL28_RS03295 (NCTC12050_00642) sodA 637143..637748 (+) 606 WP_002983977.1 superoxide dismutase SodA -
  DQL28_RS03300 (NCTC12050_00643) - 637915..638142 (+) 228 WP_011054657.1 hypothetical protein -
  DQL28_RS03305 (NCTC12050_00644) - 638127..638375 (+) 249 WP_011054656.1 hypothetical protein -
  DQL28_RS09670 (NCTC12050_00645) - 638372..638665 (+) 294 WP_306460904.1 hypothetical protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24607.41 Da        Isoelectric Point: 6.7451

>NTDB_id=1018075 DQL28_RS03280 WP_030126965.1 633049..633711(+) (comEA/celA/cilE) [Streptococcus pyogenes strain NCTC12050]
MLDELLIKGKSFLRERYFPPYLISLLLGLFLILSFSFLFWGNRQSKAAVPALREISPVKQQVSEEKKEIQEDNSILVDLK
GAVQKEGVYKLTASSRVRDVIELAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIFLD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=1018075 DQL28_RS03280 WP_030126965.1 633049..633711(+) (comEA/celA/cilE) [Streptococcus pyogenes strain NCTC12050]
ATGTTAGATGAATTATTAATTAAAGGAAAATCGTTTTTGAGAGAGCGGTATTTTCCGCCATACCTAATTAGTCTTTTATT
AGGACTTTTTCTAATACTAAGCTTCAGTTTTTTGTTCTGGGGAAATAGGCAGAGCAAGGCAGCCGTTCCTGCTTTGAGAG
AAATATCGCCTGTGAAACAGCAGGTTAGTGAAGAAAAAAAGGAAATTCAAGAAGATAACAGTATTTTAGTGGATTTAAAA
GGCGCCGTACAAAAAGAGGGAGTTTATAAGCTAACTGCTAGCAGTCGTGTGCGAGATGTCATTGAACTAGCTGGAGGCCT
AACTTCAGAAGCTGATAAACATGCTATTAATTTTGCAGAAAAACTAACTGATGAGCAAGTTGTTTATGTACCTAAACAAG
GAGAAGAGATTTCTGTGCTACCAAGATCATTAGTTTCTGGTAAAAAAGAAACTGCCAGCAAGGATCAGTCAAAGGTTCAT
ATTAATAAGGCCAGCTTAGAAGAACTACAACATATCCCAGGTATTGGTGCTAAAAGAGCTCAGGATATTATTGATATGAG
AGATAAGTTAGGTGGTTTTAAAGCGTTAGAAGATCTCCGTCAGGTTTCGGGGATTGGCGAAAAAACGCTCGAGAAATTAA
AAGATGACATTTTCTTGGACTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(156-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.995

94.091

0.405