Detailed information NTG1017928

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: DQM36_RS09170
• Genome accession: NZ_LS483332
• Coordinates: 1769295..1770062 (-)
• Length: 255 a.a.
• NCBI ID: WP_003058809.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC12696
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1764295..1775062

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM36_RS09155 (NCTC12696_01805)	hexB	1764826..1766808 (-)	1983	WP_002992189.1	DNA mismatch repair endonuclease MutL	Machinery gene
DQM36_RS09160 (NCTC12696_01806)	-	1766903..1768054 (-)	1152	WP_003058754.1	tyrosine-type recombinase/integrase	-
DQM36_RS09890	-	1768303..1768446 (+)	144	WP_011185066.1	putative holin-like toxin	-
DQM36_RS09170 (NCTC12696_01808)	irvR	1769295..1770062 (-)	768	WP_003058809.1	helix-turn-helix transcriptional regulator	Regulator
DQM36_RS09175 (NCTC12696_01809)	-	1770216..1770422 (+)	207	WP_002992503.1	helix-turn-helix transcriptional regulator	-
DQM36_RS09180 (NCTC12696_01810)	-	1770456..1770656 (+)	201	WP_002992502.1	helix-turn-helix domain-containing protein	-
DQM36_RS09185 (NCTC12696_01811)	-	1770677..1771084 (+)	408	WP_002992501.1	hypothetical protein	-
DQM36_RS09895 (NCTC12696_01812)	-	1771097..1771219 (+)	123	WP_011285272.1	hypothetical protein	-
DQM36_RS09190 (NCTC12696_01813)	-	1771502..1772023 (+)	522	WP_002992498.1	Rha family transcriptional regulator	-
DQM36_RS09195 (NCTC12696_01814)	-	1772268..1772600 (+)	333	WP_002992497.1	hypothetical protein	-
DQM36_RS09200 (NCTC12696_01815)	-	1772600..1772791 (+)	192	WP_027968868.1	hypothetical protein	-
DQM36_RS09205 (NCTC12696_01816)	-	1772804..1773166 (+)	363	WP_000206026.1	hypothetical protein	-
DQM36_RS09210 (NCTC12696_01817)	-	1773163..1773492 (+)	330	WP_000174505.1	hypothetical protein	-
DQM36_RS09215 (NCTC12696_01818)	-	1773495..1773767 (+)	273	WP_001100459.1	hypothetical protein	-
DQM36_RS09220 (NCTC12696_01819)	-	1773768..1774625 (+)	858	WP_011185073.1	primase alpha helix C-terminal domain-containing protein	-

Sequence

Protein

• Length: 255 a.a.
• Molecular weight: 28725.00 Da
• Isoelectric Point: 4.3544

>NTDB_id=1017928 DQM36_RS09170 WP_003058809.1 1769295..1770062(-) (irvR) [Streptococcus pyogenes strain NCTC12696]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide

• Length: 768 bp

>NTDB_id=1017928 DQM36_RS09170 WP_003058809.1 1769295..1770062(-) (irvR) [Streptococcus pyogenes strain NCTC12696]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAATTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCGTTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (23-68)

• Peptidase S24-like (Peptidase_S24) (141-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	34	100	0.4