Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   DQL10_RS05335 Genome accession   NZ_LS483331
Coordinates   1028908..1029696 (+) Length   262 a.a.
NCBI ID   WP_021341138.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC12057     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1023908..1034696
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL10_RS05290 (NCTC12057_01048) - 1024356..1024799 (-) 444 WP_012560973.1 hypothetical protein -
  DQL10_RS05295 (NCTC12057_01049) - 1024855..1025235 (+) 381 WP_000568478.1 hypothetical protein -
  DQL10_RS05300 (NCTC12057_01050) - 1025225..1025497 (-) 273 WP_000370473.1 hypothetical protein -
  DQL10_RS05305 (NCTC12057_01051) - 1025670..1025849 (-) 180 WP_012560974.1 hypothetical protein -
  DQL10_RS09545 (NCTC12057_01052) - 1025980..1026114 (-) 135 WP_021340229.1 hypothetical protein -
  DQL10_RS05310 (NCTC12057_01053) - 1026111..1026407 (-) 297 WP_021733370.1 MerR family transcriptional regulator -
  DQL10_RS09340 (NCTC12057_01054) - 1026543..1026686 (+) 144 WP_021341082.1 hypothetical protein -
  DQL10_RS05315 (NCTC12057_01056) - 1026849..1027088 (-) 240 WP_021341081.1 helix-turn-helix domain-containing protein -
  DQL10_RS05320 (NCTC12057_01057) - 1027182..1027853 (+) 672 WP_014635527.1 DUF4145 domain-containing protein -
  DQL10_RS09550 (NCTC12057_01058) - 1027810..1027935 (-) 126 WP_014635528.1 hypothetical protein -
  DQL10_RS05325 (NCTC12057_01059) - 1027970..1028128 (-) 159 WP_014635529.1 hypothetical protein -
  DQL10_RS05330 (NCTC12057_01060) - 1028187..1028402 (+) 216 WP_014635530.1 hypothetical protein -
  DQL10_RS09345 (NCTC12057_01061) - 1028388..1028537 (-) 150 WP_014635531.1 hypothetical protein -
  DQL10_RS05335 (NCTC12057_01063) irvR 1028908..1029696 (+) 789 WP_021341138.1 S24 family peptidase Regulator
  DQL10_RS05340 (NCTC12057_01064) - 1029775..1030671 (+) 897 WP_021341136.1 ATP-binding protein -
  DQL10_RS05345 (NCTC12057_01065) - 1030686..1031045 (+) 360 WP_021341135.1 STAS-like domain-containing protein -
  DQL10_RS05350 (NCTC12057_01066) - 1031042..1031587 (+) 546 WP_021341137.1 type II toxin-antitoxin system VapC family toxin -
  DQL10_RS05355 (NCTC12057_01067) - 1031707..1032795 (+) 1089 WP_021341141.1 site-specific integrase -
  DQL10_RS05360 (NCTC12057_01068) - 1033158..1033778 (+) 621 WP_002989605.1 DUF3862 domain-containing protein -

Sequence

Protein


Download         Length: 262 a.a.        Molecular weight: 30066.25 Da        Isoelectric Point: 8.7580

>NTDB_id=1017788 DQL10_RS05335 WP_021341138.1 1028908..1029696(+) (irvR) [Streptococcus pyogenes strain NCTC12057]
MARGRGKLTPQDEEYKKIISAKINSLLLENNLKQGHLADALEIPRSSFNEYVKGNSLPNPGNVQKIADYFGLMKSDIDPR
FAPRKKNHELKIPTSPLVKKITTTVVELNVPRKQKVLDFATEQLKEQKNKITSIEKKLYEYKVYEKLSAGTGYGYFGDGN
YDTVFYDEELDYDFASWVFGDSMEPTYLNGEVVLIKQTGFDYEGGIYAVEWDGQTYIKKVYREKDGLRLVSLNKKYSDKF
APFSEDPRIIGKIVGNFMPKEY

Nucleotide


Download         Length: 789 bp        

>NTDB_id=1017788 DQL10_RS05335 WP_021341138.1 1028908..1029696(+) (irvR) [Streptococcus pyogenes strain NCTC12057]
ATGGCAAGAGGACGAGGGAAATTAACACCTCAAGACGAGGAATACAAAAAGATAATTTCTGCTAAAATTAACAGTTTATT
GCTAGAAAACAATTTAAAACAAGGACATTTAGCTGATGCATTGGAAATTCCACGAAGTAGTTTTAATGAATATGTCAAAG
GAAATTCCTTACCTAATCCTGGTAACGTTCAAAAGATAGCTGATTATTTCGGGTTAATGAAGTCTGATATAGATCCTAGA
TTTGCACCTCGTAAGAAAAATCACGAACTCAAAATCCCTACTTCTCCACTCGTCAAAAAAATAACCACAACAGTTGTAGA
ATTAAATGTTCCTCGTAAACAAAAAGTTTTAGACTTTGCAACAGAACAATTGAAAGAACAAAAAAATAAGATTACTTCGA
TAGAGAAAAAACTATACGAGTACAAAGTCTATGAGAAACTTTCTGCGGGTACAGGTTATGGATATTTTGGTGATGGGAAC
TATGATACTGTTTTTTACGACGAAGAATTAGATTACGATTTTGCCTCTTGGGTTTTTGGTGATTCTATGGAGCCAACTTA
TTTAAATGGTGAAGTTGTTCTTATAAAACAAACTGGCTTTGATTATGAAGGTGGCATCTATGCCGTAGAATGGGACGGAC
AAACCTATATTAAGAAAGTTTATAGAGAAAAGGATGGCTTGCGCCTTGTATCCTTAAATAAAAAATACAGTGACAAGTTT
GCTCCTTTTAGTGAAGATCCTCGAATAATAGGGAAAATTGTCGGTAACTTTATGCCGAAAGAATATTAA

Domains

Predicted by InterProScan.

Peptidase S24-like (Peptidase_S24)

(168-254)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

38.158

100

0.443