Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   DQL10_RS03945 Genome accession   NZ_LS483331
Coordinates   765577..766053 (+) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain NCTC12057     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 760577..771053
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL10_RS03920 (NCTC12057_00772) - 760615..761403 (+) 789 WP_023611986.1 Nif3-like dinuclear metal center hexameric protein -
  DQL10_RS03925 (NCTC12057_00773) - 761443..762552 (+) 1110 WP_023612028.1 NAD(P)/FAD-dependent oxidoreductase -
  DQL10_RS03930 (NCTC12057_00774) rfbA 762610..763479 (+) 870 WP_023612014.1 glucose-1-phosphate thymidylyltransferase RfbA -
  DQL10_RS03935 (NCTC12057_00775) - 763479..764072 (+) 594 WP_002990099.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  DQL10_RS03940 (NCTC12057_00776) rfbB 764316..765356 (+) 1041 WP_023612000.1 dTDP-glucose 4,6-dehydratase -
  DQL10_RS03945 (NCTC12057_00777) mutX 765577..766053 (+) 477 WP_002984880.1 NUDIX hydrolase Machinery gene
  DQL10_RS03950 (NCTC12057_00778) - 766111..767292 (+) 1182 WP_011284730.1 AI-2E family transporter -
  DQL10_RS03955 (NCTC12057_00779) - 767282..768529 (+) 1248 WP_050336178.1 tetratricopeptide repeat protein -
  DQL10_RS03960 (NCTC12057_00780) fbp54 768588..770240 (-) 1653 WP_023612033.1 Rqc2 family fibronectin-binding protein Fbp54 -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=1017778 DQL10_RS03945 WP_002984880.1 765577..766053(+) (mutX) [Streptococcus pyogenes strain NCTC12057]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=1017778 DQL10_RS03945 WP_002984880.1 765577..766053(+) (mutX) [Streptococcus pyogenes strain NCTC12057]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCCGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703