Detailed information NTG1017729

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: DQL25_RS09210
• Genome accession: NZ_LS483330
• Coordinates: 1798950..1801505 (-)
• Length: 851 a.a.
• NCBI ID: WP_111703705.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC8328
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1793950..1806505

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL25_RS09170 (NCTC8328_01823)	-	1794928..1795182 (+)	255	WP_011285280.1	hypothetical protein	-
DQL25_RS09175 (NCTC8328_01824)	-	1795179..1795352 (+)	174	WP_011285281.1	hypothetical protein	-
DQL25_RS09635 (NCTC8328_01825)	-	1795358..1795531 (+)	174	WP_014635784.1	hypothetical protein	-
DQL25_RS09180 (NCTC8328_01826)	-	1795533..1796042 (+)	510	WP_014407945.1	hypothetical protein	-
DQL25_RS09185 (NCTC8328_01827)	-	1796117..1796605 (+)	489	WP_002992480.1	hypothetical protein	-
DQL25_RS09195 (NCTC8328_01828)	-	1797009..1797371 (+)	363	WP_020905578.1	DUF1492 domain-containing protein	-
DQL25_RS09200 (NCTC8328_01829)	-	1797346..1797729 (+)	384	WP_014407948.1	ArpU family phage packaging/lysis transcriptional regulator	-
DQL25_RS09205 (NCTC8328_01830)	-	1797935..1798552 (+)	618	WP_227875684.1	hypothetical protein	-
DQL25_RS09210 (NCTC8328_01831)	hexA	1798950..1801505 (-)	2556	WP_111703705.1	DNA mismatch repair protein MutS	Machinery gene
DQL25_RS09805 (NCTC8328_01832)	-	1801492..1801698 (-)	207	WP_111703707.1	YlbF family regulator	-
DQL25_RS09220 (NCTC8328_01833)	argR	1801841..1802278 (-)	438	WP_111703709.1	arginine repressor	-
DQL25_RS09225 (NCTC8328_01834)	argS	1802569..1804260 (+)	1692	WP_111703710.1	arginine--tRNA ligase	-
DQL25_RS09230 (NCTC8328_01835)	-	1804348..1804656 (+)	309	WP_002991370.1	bacteriocin immunity protein	-
DQL25_RS09235 (NCTC8328_01836)	-	1804683..1805555 (-)	873	WP_002982164.1	YitT family protein	-
DQL25_RS09240 (NCTC8328_01837)	-	1805598..1806476 (-)	879	WP_011889240.1	YitT family protein	-

Sequence

Protein

• Length: 851 a.a.
• Molecular weight: 95502.97 Da
• Isoelectric Point: 4.9487

>NTDB_id=1017729 DQL25_RS09210 WP_111703705.1 1798950..1801505(-) (hexA) [Streptococcus pyogenes strain NCTC8328]
MAKTNISPGMQQYLDIKKDYPDAFLLFRMGDFYELFYDDAVKAAQLLEIGLTSRNKNAENPIPMAGVPHHSAQQYIDVLI
ELGYKVAVAEQMEDPKQAVGVVKREVVQVITPGTVVDSAKPDSANNFLVAVDFDGCRYGLAYMDVSTGEFCVTDLADFTS
VRSEIQNLKAKEVLLGFDLSEEEQTILVKQMNLLLSYEETVYEDKSLIDGQLTTVELTAAGKLLQYVHKTQMRELSHLQA
LVHYEIKDYLQMSYATKSSLDLVENARTNKKHGSLYWLLDETKTAMGMRLLRSWIDRPLVSKEAILERQEIIQVFLNAFI
ERTDLSNSLKGVYDIERLSSRVSFGKANPKDLLQLGHTLAQVPYIKAILESFDSPCVDKLVNDIDSLPELEYLIRTAIDP
DAPATISEGSIIRNGFDERLDHYRKVMREGTGWIADIEAKERQESGINNLKIDYNKKDGYYFHVTTSNLSLVPEHFFRKA
TLKNSERYGTAELAKIEGQMLEAREESSSLEYDIFMCIRAQVETYINRLQKLAKTLATVDVLQSLAVVAETNHYIRPQFN
DNHVITIQEGRHAVVEKVMGVQEYIPNSISFDQQTSIQLITGPNMSGKSTYMRQLALTVIMAQMGSFVAADHVDLPLFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKRASDNSLILFDELGRGTATYDGMALAQAIIEYIHDRVGAKTIFATHYHEL
TDLSTKLTSLVNVHVATLEKDGDVTFLHKIAEGPADKSYGIHVAKIAGLPKSLLKRADEVLTRLETQSRSTEIISVPSQV
ESSNAVRQGQLSLFGDEEKAHEIRQALEAIDVMNMTPLQAMTTLYELKKLL

Nucleotide

• Length: 2556 bp

>NTDB_id=1017729 DQL25_RS09210 WP_111703705.1 1798950..1801505(-) (hexA) [Streptococcus pyogenes strain NCTC8328]
ATGGCAAAAACTAACATTTCTCCTGGAATGCAACAGTATCTGGACATCAAAAAAGATTATCCAGATGCTTTTTTGCTTTT
TAGGATGGGTGACTTTTATGAATTATTTTATGATGATGCTGTCAAAGCAGCACAACTCTTAGAAATTGGTTTGACCAGTC
GCAACAAGAATGCGGAAAATCCAATTCCCATGGCAGGCGTGCCACATCATTCTGCCCAACAATACATTGATGTGTTAATT
GAGTTGGGTTACAAGGTTGCTGTCGCAGAACAAATGGAAGACCCAAAGCAAGCTGTTGGGGTGGTGAAGCGTGAGGTCGT
TCAAGTCATAACTCCTGGAACGGTTGTGGATTCAGCTAAGCCAGATAGCGCCAATAACTTTTTGGTAGCTGTTGACTTTG
ATGGTTGCCGTTATGGATTGGCTTATATGGATGTATCCACAGGTGAATTTTGCGTGACAGATTTGGCGGACTTTACGAGT
GTTCGTAGCGAAATCCAAAACCTCAAGGCAAAAGAAGTCTTACTAGGTTTTGATTTATCTGAAGAAGAACAGACGATTTT
GGTCAAGCAGATGAATTTGCTGCTTTCTTATGAAGAAACGGTCTATGAAGATAAATCTTTAATTGACGGCCAATTGACAA
CGGTAGAACTGACAGCGGCAGGAAAACTCTTGCAATACGTTCACAAAACACAAATGCGAGAACTCAGCCACTTGCAAGCA
TTGGTTCACTATGAGATCAAGGATTATTTGCAGATGTCGTATGCCACTAAGTCAAGTTTAGATTTGGTAGAAAATGCTAG
GACTAATAAAAAACATGGAAGTCTCTATTGGCTGTTAGATGAAACCAAGACAGCTATGGGGATGAGGCTTTTGCGCTCAT
GGATTGATCGACCTTTGGTTTCTAAAGAAGCTATTTTAGAGCGTCAAGAAATTATTCAAGTTTTTCTGAATGCTTTTATT
GAGCGAACCGATTTAAGCAATAGTTTAAAAGGTGTTTACGACATCGAACGCTTATCTAGTCGCGTGTCTTTTGGCAAGGC
AAATCCGAAAGATTTACTTCAATTGGGGCATACCTTAGCCCAAGTGCCTTATATCAAAGCTATCTTAGAGTCTTTTGACA
GTCCTTGTGTTGACAAACTTGTCAATGATATTGACAGTTTGCCTGAGTTGGAATACTTGATTAGAACAGCCATTGATCCA
GATGCACCAGCAACTATTAGTGAAGGAAGTATTATCCGCAATGGTTTTGATGAGCGCTTGGACCATTATCGTAAAGTAAT
GCGAGAGGGGACAGGCTGGATTGCGGATATTGAGGCCAAAGAGCGTCAAGAAAGTGGCATTAATAACCTAAAAATTGATT
ACAATAAAAAAGATGGTTATTATTTTCACGTTACGACTTCAAATCTTAGCTTAGTTCCCGAGCATTTTTTCAGAAAGGCA
ACTTTAAAAAATTCTGAACGTTATGGAACAGCAGAATTGGCTAAGATTGAAGGTCAGATGTTAGAGGCTAGGGAAGAGTC
ATCTAGTTTAGAATACGATATTTTTATGTGTATTCGAGCTCAAGTTGAAACCTATATTAATCGTTTACAGAAACTGGCTA
AAACTTTGGCAACGGTGGATGTTTTGCAAAGTTTAGCAGTCGTTGCTGAAACCAATCATTATATCCGGCCGCAGTTCAAT
GATAATCATGTGATTACAATTCAAGAAGGTCGTCACGCGGTTGTTGAAAAGGTTATGGGAGTGCAGGAATACATTCCCAA
TAGTATCTCTTTTGACCAACAGACCAGTATTCAGCTGATTACAGGTCCAAATATGAGTGGTAAGTCGACTTATATGAGAC
AGCTGGCCTTAACGGTTATCATGGCCCAGATGGGTTCATTTGTGGCTGCTGACCATGTTGATTTACCTTTATTTGATGCG
ATTTTTACGCGTATTGGGGCTGCTGATGATTTGATTTCTGGGCAATCAACCTTTATGGTGGAGATGATGGAAGCAAACCA
AGCAATCAAACGCGCAAGTGACAACTCTCTTATTCTATTTGATGAACTGGGCCGAGGTACGGCAACTTATGATGGTATGG
CTTTAGCCCAGGCAATTATTGAATATATCCATGATAGAGTTGGTGCTAAGACCATATTTGCAACGCATTATCATGAATTG
ACAGACTTGTCAACTAAGTTGACAAGTCTAGTCAATGTTCATGTAGCAACGCTTGAAAAAGATGGCGATGTTACCTTCCT
TCATAAGATTGCTGAGGGACCGGCGGATAAATCTTACGGTATTCATGTGGCAAAAATAGCAGGACTGCCAAAATCCCTAT
TAAAGAGAGCAGACGAAGTTCTGACCCGTTTAGAAACACAGTCACGATCTACTGAGATAATATCAGTCCCTTCACAAGTT
GAGTCAAGCAACGCTGTTAGACAGGGGCAATTATCCCTTTTTGGTGATGAAGAGAAAGCTCATGAGATTAGGCAAGCACT
GGAAGCTATTGATGTCATGAACATGACCCCGCTTCAAGCAATGACAACCCTTTACGAATTGAAAAAGTTGTTATAG

Domains

Predicted by InterProScan.

• MutS domain III (MutS_III) (256-546)

• MutS domain II (MutS_II) (126-239)

• MutS family domain IV (MutS_IV) (415-506)

• MutS domain I (MutS_I) (8-118)

• MutS domain V (MutS_V) (599-785)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	71.093	100	0.711
mutS	Pseudomonas stutzeri strain ATCC 17587	37.193	100	0.374