Detailed information NTG1017632

Bioinformatically predicted

Overview

• Name: irvR
• Type: Regulator
• Locus tag: DQL27_RS08550
• Genome accession: NZ_LS483329
• Coordinates: 1692078..1692845 (-)
• Length: 255 a.a.
• NCBI ID: WP_003058809.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain NCTC12058
• Function: regulate expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1687078..1697845

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL27_RS08535 (NCTC12058_01690)	hexB	1687587..1689569 (-)	1983	WP_031488761.1	DNA mismatch repair endonuclease MutL	Machinery gene
DQL27_RS08540 (NCTC12058_01691)	-	1689664..1690815 (-)	1152	WP_014635780.1	tyrosine-type recombinase/integrase	-
DQL27_RS09230	-	1691064..1691207 (+)	144	WP_011185066.1	putative holin-like toxin	-
DQL27_RS08550 (NCTC12058_01693)	irvR	1692078..1692845 (-)	768	WP_003058809.1	helix-turn-helix transcriptional regulator	Regulator
DQL27_RS08555 (NCTC12058_01694)	-	1692999..1693205 (+)	207	WP_002992503.1	helix-turn-helix transcriptional regulator	-
DQL27_RS08560 (NCTC12058_01695)	-	1693239..1694006 (+)	768	WP_080277853.1	Bro-N domain-containing protein	-
DQL27_RS08565 (NCTC12058_01696)	-	1694016..1694639 (+)	624	WP_010922760.1	phage repressor protein	-
DQL27_RS08570 (NCTC12058_01697)	-	1694666..1694908 (+)	243	WP_000648623.1	hypothetical protein	-
DQL27_RS08575 (NCTC12058_01698)	-	1695164..1695505 (+)	342	WP_010922762.1	hypothetical protein	-
DQL27_RS08580 (NCTC12058_01699)	-	1695492..1695713 (+)	222	WP_010922763.1	hypothetical protein	-
DQL27_RS08585 (NCTC12058_01700)	-	1695716..1695907 (+)	192	WP_010922764.1	hypothetical protein	-
DQL27_RS08590 (NCTC12058_01701)	-	1695919..1696248 (+)	330	WP_003058810.1	hypothetical protein	-
DQL27_RS08595 (NCTC12058_01702)	-	1696251..1696523 (+)	273	WP_001100459.1	hypothetical protein	-
DQL27_RS08600 (NCTC12058_01703)	-	1696524..1697381 (+)	858	WP_010922767.1	primase alpha helix C-terminal domain-containing protein	-

Sequence

Protein

• Length: 255 a.a.
• Molecular weight: 28725.00 Da
• Isoelectric Point: 4.3544

>NTDB_id=1017632 DQL27_RS08550 WP_003058809.1 1692078..1692845(-) (irvR) [Streptococcus pyogenes strain NCTC12058]
MAKNSPQDLINREIFSTNLNMLMAKKNIKQIDIHNKLGIPKSTITGYVKGRSLPTAGNVQKLADFFGVLKSDIDPRFDSN
NIETNSNIIPSTLQKVTSTLSQLEHKRQLNVLDYAETQLEQQNTVEEPQATYYTYNYYDHAASAGTGQYLNDVQVETIEL
PVDYDADFVIPVYGDSMEPEYHSGDYVFIKLSINLSDGDIGVFEYYGDAYIKQLVINDSGAFLHSLNDKYDDILIDRDSD
FRIIGEVIGSFTSKS

Nucleotide

• Length: 768 bp

>NTDB_id=1017632 DQL27_RS08550 WP_003058809.1 1692078..1692845(-) (irvR) [Streptococcus pyogenes strain NCTC12058]
ATGGCTAAAAATAGTCCCCAAGATTTAATAAATAGAGAAATTTTCTCAACAAATCTCAACATGCTTATGGCTAAAAAGAA
TATCAAACAGATAGATATTCACAACAAACTAGGAATACCTAAGAGTACGATAACTGGCTATGTTAAAGGTCGTTCACTCC
CAACTGCTGGAAACGTTCAAAAGCTGGCGGACTTCTTCGGAGTTCTAAAATCAGACATTGACCCCCGTTTTGATTCTAAT
AATATTGAAACAAATAGTAATATTATCCCATCAACCCTACAAAAAGTAACATCTACTTTATCTCAGCTAGAACACAAGCG
ACAATTAAACGTCCTTGATTATGCTGAAACACAATTAGAACAACAAAACACAGTAGAAGAACCACAAGCCACCTACTACA
CTTACAATTACTACGACCACGCAGCTTCAGCTGGTACAGGTCAGTATCTAAATGATGTACAAGTAGAAACAATTGAATTA
CCAGTCGATTACGACGCTGATTTTGTCATACCGGTTTATGGCGATTCTATGGAACCCGAATACCATTCTGGGGACTATGT
ATTTATCAAACTATCTATTAACCTGTCAGATGGTGATATAGGAGTTTTTGAGTATTACGGTGATGCTTATATCAAACAAC
TTGTTATAAACGATTCTGGAGCATTTCTGCATAGTCTGAACGACAAGTATGACGATATACTCATAGATAGAGATAGTGAT
TTCCGTATTATCGGAGAAGTTATTGGGAGTTTTACATCTAAATCATGA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (23-68)

• Peptidase S24-like (Peptidase_S24) (141-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
irvR	Streptococcus mutans UA159	34	100	0.4