Detailed information    

insolico Bioinformatically predicted

Overview

Name   ruvA   Type   Machinery gene
Locus tag   DQL27_RS08525 Genome accession   NZ_LS483329
Coordinates   1685758..1686354 (-) Length   198 a.a.
NCBI ID   WP_031488763.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC12058     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1680758..1691354
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL27_RS08490 (NCTC12058_01681) - 1680818..1681123 (-) 306 WP_002982199.1 DUF1292 domain-containing protein -
  DQL27_RS08495 (NCTC12058_01682) ruvX 1681135..1681554 (-) 420 WP_111711511.1 Holliday junction resolvase RuvX -
  DQL27_RS08500 (NCTC12058_01683) - 1681551..1681820 (-) 270 WP_002982194.1 IreB family regulatory phosphoprotein -
  DQL27_RS08505 (NCTC12058_01684) spx 1681934..1682332 (-) 399 WP_002982188.1 transcriptional regulator Spx -
  DQL27_RS08510 (NCTC12058_01685) recA 1682623..1683759 (-) 1137 WP_002992179.1 recombinase RecA Machinery gene
  DQL27_RS08515 (NCTC12058_01686) cinA 1683848..1685119 (-) 1272 WP_010922754.1 competence/damage-inducible protein A Machinery gene
  DQL27_RS08520 (NCTC12058_01687) - 1685188..1685748 (-) 561 WP_023079151.1 DNA-3-methyladenine glycosylase I -
  DQL27_RS08525 (NCTC12058_01688) ruvA 1685758..1686354 (-) 597 WP_031488763.1 Holliday junction branch migration protein RuvA Machinery gene
  DQL27_RS08530 (NCTC12058_01689) - 1686356..1687576 (-) 1221 WP_111711512.1 MDR family MFS transporter -
  DQL27_RS08535 (NCTC12058_01690) hexB 1687587..1689569 (-) 1983 WP_031488761.1 DNA mismatch repair endonuclease MutL Machinery gene
  DQL27_RS08540 (NCTC12058_01691) - 1689664..1690815 (-) 1152 WP_014635780.1 tyrosine-type recombinase/integrase -
  DQL27_RS09230 - 1691064..1691207 (+) 144 WP_011185066.1 putative holin-like toxin -

Sequence

Protein


Download         Length: 198 a.a.        Molecular weight: 21873.17 Da        Isoelectric Point: 5.7438

>NTDB_id=1017630 DQL27_RS08525 WP_031488763.1 1685758..1686354(-) (ruvA) [Streptococcus pyogenes strain NCTC12058]
MYDYIKGQLTKITAKYIVVEANGLGYMINVANPYSFTDSVNQLVTIYLHQVIREDAHLLFGFHTEDEKDVFLKLISVSGI
GPTTALAIVAVDDNEGLVNAIDNSDIKYLMKFPKIGKKTAQQMVLDLDGKFVEAPQETGNTKARSNKAGNTQLDEAIEAL
LALGYKATELKKIRAFFEGTSETAEQYIKSALKLLMKG

Nucleotide


Download         Length: 597 bp        

>NTDB_id=1017630 DQL27_RS08525 WP_031488763.1 1685758..1686354(-) (ruvA) [Streptococcus pyogenes strain NCTC12058]
ATGTACGATTATATTAAAGGTCAATTGACCAAAATTACGGCAAAATACATTGTCGTTGAAGCTAATGGATTGGGCTACAT
GATTAATGTTGCCAATCCTTATAGCTTTACAGATAGTGTCAACCAATTGGTAACCATTTATCTGCATCAAGTGATTCGTG
AGGATGCTCACCTGTTGTTTGGTTTTCACACGGAAGATGAAAAAGATGTTTTTCTGAAATTAATTTCTGTATCAGGTATT
GGTCCGACAACAGCTCTTGCTATTGTGGCAGTTGATGATAATGAGGGACTTGTGAATGCCATTGATAACAGTGACATTAA
GTACCTAATGAAATTTCCTAAAATTGGTAAAAAAACAGCGCAGCAAATGGTTCTTGACTTAGATGGCAAATTTGTGGAGG
CTCCACAAGAGACTGGTAATACCAAAGCGCGCAGCAATAAAGCAGGCAATACTCAACTGGACGAAGCGATTGAAGCCCTC
CTTGCCCTCGGTTATAAGGCAACGGAATTGAAGAAAATTCGTGCCTTCTTTGAAGGAACCTCTGAGACAGCCGAACAATA
CATCAAATCAGCCCTTAAACTATTAATGAAAGGCTAG

Domains

Predicted by InterProScan.

RuvA N terminal domain (RuvA_N)

(1-61)

Helix-hairpin-helix domain (HHH_5)

(71-127)

RuvA, C-terminal domain (RuvA_C)

(152-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ruvA Streptococcus pneumoniae TIGR4

66.497

99.495

0.662
  ruvA Streptococcus pneumoniae R6

66.497

99.495

0.662
  ruvA Streptococcus pneumoniae D39

66.497

99.495

0.662
  ruvA Bacillus subtilis subsp. subtilis str. 168

41.379

100

0.424

Multiple sequence alignment