Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   DQL59_RS04445 Genome accession   NZ_LS483326
Coordinates   874911..875573 (-) Length   220 a.a.
NCBI ID   WP_111681168.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC12045     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 869911..880573
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL59_RS04420 (NCTC12045_00878) - 870247..870495 (-) 249 WP_111681164.1 serine hydrolase -
  DQL59_RS04425 (NCTC12045_00879) - 870480..870707 (-) 228 WP_111681165.1 hypothetical protein -
  DQL59_RS04430 (NCTC12045_00880) sodA 870874..871479 (-) 606 WP_111681166.1 superoxide dismutase SodA -
  DQL59_RS04435 (NCTC12045_00881) holA 871576..872616 (-) 1041 WP_030126963.1 DNA polymerase III subunit delta -
  DQL59_RS04440 (NCTC12045_00882) comEC/celB 872687..874930 (-) 2244 WP_111681167.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  DQL59_RS04445 (NCTC12045_00883) comEA/celA/cilE 874911..875573 (-) 663 WP_111681168.1 ComEA family DNA-binding protein Machinery gene
  DQL59_RS04450 (NCTC12045_00884) - 875773..876513 (-) 741 WP_012560804.1 lysophospholipid acyltransferase family protein -
  DQL59_RS04455 (NCTC12045_00885) - 876631..877407 (+) 777 WP_011888792.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  DQL59_RS04460 (NCTC12045_00886) - 877397..877675 (+) 279 WP_011017953.1 GIY-YIG nuclease family protein -
  DQL59_RS04465 (NCTC12045_00887) - 877698..879698 (-) 2001 WP_111681169.1 potassium transporter Kup -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24626.45 Da        Isoelectric Point: 6.7451

>NTDB_id=1017385 DQL59_RS04445 WP_111681168.1 874911..875573(-) (comEA/celA/cilE) [Streptococcus pyogenes strain NCTC12045]
MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQSKAAVPTLREISPVKQQVSEEKKEIQEDSSILVDLK
GAVQKEGVYKLTASSRVRDVIELAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIFLD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=1017385 DQL59_RS04445 WP_111681168.1 874911..875573(-) (comEA/celA/cilE) [Streptococcus pyogenes strain NCTC12045]
ATGTTAGACGAATTATTAATTAAAGGAAAATCGTTTTTGAGAGAGCGGTATTTTCTGCCATACCTAATTAGTCTTTTATT
AGGACTTTTTCTAATACTAAGCTTCAGTTTTTTGTTCTGGGGAAATAGGCAGAGCAAGGCAGCCGTTCCTACTTTGAGAG
AAATATCGCCTGTGAAACAGCAGGTTAGTGAAGAAAAAAAGGAAATTCAAGAAGATAGCAGTATTTTAGTGGATTTAAAA
GGCGCCGTACAAAAAGAGGGAGTTTATAAGCTAACTGCTAGCAGTCGTGTGCGAGATGTCATTGAACTAGCTGGAGGCCT
AACTTCAGAAGCTGATAAACATGCTATTAATTTTGCAGAAAAACTAACTGATGAGCAAGTTGTTTATGTACCTAAACAAG
GAGAAGAGATTTCTGTGCTACCAAGATCATTAGTTTCTGGTAAAAAAGAAACTGCCAGCAAGGATCAGTCAAAGGTTCAT
ATTAATAAGGCCAGCTTAGAAGAACTACAACATATCCCAGGTATTGGTGCTAAAAGAGCTCAGGATATTATTGATATGAG
AGATAAGTTAGGTGGTTTTAAAGCGTTAGAAGATCTCCGTCAGGTTTCGGGGATTGGCGAAAAAACGCTCGAGAAATTAA
AAGATGACATTTTCTTGGACTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(156-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.995

94.091

0.405

Multiple sequence alignment