Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ABXO38_RS12875 Genome accession   NZ_CP160024
Coordinates   2629309..2630025 (-) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain 23EV612     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2624309..2635025
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABXO38_RS12855 (ABXO38_12845) - 2625401..2626351 (+) 951 WP_000790329.1 LacI family DNA-binding transcriptional regulator -
  ABXO38_RS12860 (ABXO38_12850) - 2626500..2627984 (+) 1485 WP_000141427.1 sucrose-6-phosphate hydrolase -
  ABXO38_RS12865 (ABXO38_12855) - 2627981..2628940 (+) 960 WP_001253302.1 carbohydrate kinase -
  ABXO38_RS12870 (ABXO38_12860) - 2629128..2629237 (-) 110 Protein_2491 hypothetical protein -
  ABXO38_RS12875 (ABXO38_12865) agrA 2629309..2630025 (-) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  ABXO38_RS12880 (ABXO38_12870) agrC 2630044..2631336 (-) 1293 WP_000387809.1 quorum-sensing sensor histidine kinase AgrC -
  ABXO38_RS12885 (ABXO38_12875) agrD 2631361..2631501 (-) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  ABXO38_RS12890 (ABXO38_12880) - 2631505..2632068 (-) 564 WP_001105705.1 accessory gene regulator AgrB -
  ABXO38_RS12895 hld 2632358..2632438 (+) 81 WP_000046023.1 delta-hemolysin -
  ABXO38_RS12900 (ABXO38_12890) - 2633037..2633822 (-) 786 WP_000867941.1 carbon-nitrogen family hydrolase -
  ABXO38_RS12905 (ABXO38_12895) - 2634183..2634809 (-) 627 WP_000522384.1 nitroreductase family protein -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=1017120 ABXO38_RS12875 WP_000688492.1 2629309..2630025(-) (agrA) [Staphylococcus aureus strain 23EV612]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=1017120 ABXO38_RS12875 WP_000688492.1 2629309..2630025(-) (agrA) [Staphylococcus aureus strain 23EV612]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment