Detailed information NTG1017039

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: AB0R62_RS14220
• Genome accession: NZ_CP160002
• Coordinates: 2776660..2777547 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain Newman D2C HOM
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2771660..2782547

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AB0R62_RS14190 (AB0R62_14190)	-	2771679..2771771 (+)	93	WP_010956583.1	hypothetical protein	-
AB0R62_RS14195 (AB0R62_14195)	-	2771879..2772376 (-)	498	WP_001065268.1	glutathione peroxidase	-
AB0R62_RS14200 (AB0R62_14200)	-	2772386..2772646 (-)	261	WP_001789910.1	hypothetical protein	-
AB0R62_RS14205 (AB0R62_14205)	-	2773028..2773141 (-)	114	WP_011447078.1	hypothetical protein	-
AB0R62_RS14210 (AB0R62_14210)	-	2773800..2775800 (-)	2001	WP_000776751.1	ABC transporter permease	-
AB0R62_RS14215 (AB0R62_14215)	-	2775797..2776552 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
AB0R62_RS14220 (AB0R62_14220)	braS	2776660..2777547 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
AB0R62_RS14225 (AB0R62_14225)	braR	2777558..2778223 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
AB0R62_RS14230 (AB0R62_14230)	-	2778249..2778449 (-)	201	WP_000604728.1	hypothetical protein	-
AB0R62_RS14235 (AB0R62_14235)	-	2778647..2780071 (+)	1425	WP_000953744.1	alkaline phosphatase	-
AB0R62_RS14240 (AB0R62_14240)	-	2780131..2780232 (-)	102	WP_000731972.1	SE2200 family small protein	-
AB0R62_RS14245 (AB0R62_14245)	-	2780354..2780809 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
AB0R62_RS14250 (AB0R62_14250)	-	2781054..2781815 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1017039 AB0R62_RS14220 WP_000143419.1 2776660..2777547(-) (braS) [Staphylococcus aureus strain Newman D2C HOM]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1017039 AB0R62_RS14220 WP_000143419.1 2776660..2777547(-) (braS) [Staphylococcus aureus strain Newman D2C HOM]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997