Detailed information NTG1016689

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: DQM44_RS00740
• Genome accession: NZ_LS483318
• Coordinates: 119960..120400 (+)
• Length: 146 a.a.
• NCBI ID: WP_003061780.1
• Uniprot ID: -
• Organism: Streptococcus dysgalactiae subsp. equisimilis strain NCTC5370
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 114960..125400

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQM44_RS00710 (NCTC5370_00147)	-	116641..117006 (+)	366	WP_003055257.1	DUF1033 family protein	-
DQM44_RS00715 (NCTC5370_00148)	comGA/cglA	117087..118028 (+)	942	WP_003062163.1	competence type IV pilus ATPase ComGA	Machinery gene
DQM44_RS00720 (NCTC5370_00149)	comGB	117964..118995 (+)	1032	WP_015057201.1	competence type IV pilus assembly protein ComGB	Machinery gene
DQM44_RS00725 (NCTC5370_00150)	comGC	118997..119323 (+)	327	WP_003055259.1	competence type IV pilus major pilin ComGC	Machinery gene
DQM44_RS00730 (NCTC5370_00151)	comGD	119298..119726 (+)	429	WP_014611932.1	competence type IV pilus minor pilin ComGD	Machinery gene
DQM44_RS00735 (NCTC5370_00152)	comGE	119734..119979 (+)	246	WP_003058569.1	competence type IV pilus minor pilin ComGE	Machinery gene
DQM44_RS00740 (NCTC5370_00153)	comGF	119960..120400 (+)	441	WP_003061780.1	competence type IV pilus minor pilin ComGF	Machinery gene
DQM44_RS00745 (NCTC5370_00154)	comGG	120429..120752 (+)	324	WP_227985720.1	competence type IV pilus minor pilin ComGG	-
DQM44_RS00750 (NCTC5370_00155)	comGH	120815..121768 (+)	954	WP_022554118.1	class I SAM-dependent methyltransferase	Machinery gene
DQM44_RS00755 (NCTC5370_00156)	-	121827..123023 (+)	1197	WP_003058485.1	acetate kinase	-
DQM44_RS00760 (NCTC5370_00157)	-	123329..123535 (+)	207	WP_003058508.1	helix-turn-helix transcriptional regulator	-
DQM44_RS00765 (NCTC5370_00158)	-	123638..124318 (+)	681	WP_003060329.1	type II CAAX endopeptidase family protein	-
DQM44_RS00770 (NCTC5370_00159)	-	124336..124773 (+)	438	WP_012766452.1	hypothetical protein	-

Sequence

Protein

• Length: 146 a.a.
• Molecular weight: 16969.55 Da
• Isoelectric Point: 10.6305

>NTDB_id=1016689 DQM44_RS00740 WP_003061780.1 119960..120400(+) (comGF) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC5370]
MKKRTGRVQAFTFLEALIALLVISGSLLVYQGLTKTLLSHSRYLTKNDQDHWLLFSQQLREELSGARFHKVENNKLYIEK
GKKKLVLGQFKSHDFRKSAGNGQGYQPMLFGLSHSHIQAEQSRIRITLHWKSGLERTFYYAFQDQP

Nucleotide

• Length: 441 bp

>NTDB_id=1016689 DQM44_RS00740 WP_003061780.1 119960..120400(+) (comGF) [Streptococcus dysgalactiae subsp. equisimilis strain NCTC5370]
TTGAAAAAAAGGACAGGTAGGGTCCAAGCATTTACTTTTTTAGAGGCTTTAATTGCCTTACTGGTGATATCAGGTTCTCT
TCTAGTGTATCAAGGATTGACCAAAACACTCCTTAGCCACAGTCGCTACCTTACCAAAAATGATCAAGACCATTGGCTTT
TGTTCTCCCAGCAGTTACGAGAAGAGTTAAGTGGAGCGCGATTTCACAAAGTAGAGAACAATAAATTATATATCGAAAAA
GGCAAGAAAAAACTAGTTTTAGGACAATTTAAAAGCCATGACTTTCGAAAATCGGCAGGCAATGGACAAGGTTATCAACC
CATGCTGTTTGGCCTGTCTCATAGTCATATACAAGCAGAGCAGTCTCGTATTCGTATTACCCTTCACTGGAAAAGTGGAC
TAGAAAGGACCTTCTACTATGCGTTTCAAGACCAACCTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (40-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	48.921	95.205	0.466
comGF	Streptococcus mutans UA140	48.201	95.205	0.459
comGF	Lactococcus lactis subsp. cremoris KW2	46.377	94.521	0.438
comGF/cglF	Streptococcus mitis NCTC 12261	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae R6	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae TIGR4	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae D39	43.796	93.836	0.411
comGF/cglF	Streptococcus mitis SK321	43.796	93.836	0.411
comGF/cglF	Streptococcus pneumoniae Rx1	43.796	93.836	0.411