Detailed information NTG1016676

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: DQL75_RS13575
• Genome accession: NZ_LS483317
• Coordinates: 2627867..2629975 (+)
• Length: 702 a.a.
• NCBI ID: WP_111762716.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain NCTC5663
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 2622867..2634975

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DQL75_RS13550 (NCTC5663_02549)	-	2622927..2623145 (+)	219	WP_000011686.1	sterile alpha motif-like domain-containing protein	-
DQL75_RS13555 (NCTC5663_02550)	-	2623540..2623971 (+)	432	WP_000455861.1	CHAP domain-containing protein	-
DQL75_RS13560 (NCTC5663_02551)	-	2624111..2625391 (-)	1281	WP_111762713.1	hydroxymethylglutaryl-CoA reductase, degradative	-
DQL75_RS13565 (NCTC5663_02552)	-	2625646..2626812 (+)	1167	WP_111762714.1	hydroxymethylglutaryl-CoA synthase	-
DQL75_RS13570 (NCTC5663_02553)	-	2626983..2627504 (-)	522	WP_111762715.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
DQL75_RS13575 (NCTC5663_02554)	clpE	2627867..2629975 (+)	2109	WP_111762716.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
DQL75_RS13580 (NCTC5663_02555)	-	2630042..2630212 (-)	171	WP_000111116.1	FeoB-associated Cys-rich membrane protein	-
DQL75_RS13585 (NCTC5663_02556)	feoB	2630225..2632219 (-)	1995	WP_111762717.1	ferrous iron transport protein B	-
DQL75_RS13590 (NCTC5663_02557)	-	2632231..2632458 (-)	228	WP_000932073.1	FeoA family protein	-

Sequence

Protein

• Length: 702 a.a.
• Molecular weight: 78150.71 Da
• Isoelectric Point: 4.7133

>NTDB_id=1016676 DQL75_RS13575 WP_111762716.1 2627867..2629975(+) (clpE) [Staphylococcus aureus strain NCTC5663]
MNNNFFNSDFDSILRRMMQDMQNSNQTSNKKYYINGKEVSPEELAQFTQQGGNHSAEQSAQAFQQAALRQQGQQSGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQQTAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISI
DISSLEAGTQYRGAFEENIQKLVEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNIMKDAALTRRFNEVLVNEPSARDTVEILKGIREKFETHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAIDKVATEKRISELEHDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDANDIERLKNISSRLRSKIIGQDKAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKEA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGTDQEYDDIMQEMKKFFRPEFLNRFNGIVEFLHLDKESLQEIINLLLDDVQVTLDKKGITMNV
SQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDLDIEDNELVVKGKS

Nucleotide

• Length: 2109 bp

>NTDB_id=1016676 DQL75_RS13575 WP_111762716.1 2627867..2629975(+) (clpE) [Staphylococcus aureus strain NCTC5663]
ATGAATAACAATTTTTTCAATAGTGACTTCGATTCTATTTTACGAAGAATGATGCAAGACATGCAAAACTCAAATCAGAC
TAGTAACAAGAAATACTATATTAATGGTAAAGAAGTTTCACCGGAAGAATTAGCACAATTTACACAACAAGGTGGTAATC
ATTCTGCCGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACTAAGACAACAAGGTCAACAAAGTGGCAATGGCAATTAT
TTAGAACAAATTGGTCGTAACTTAACGCAAGAGGCTCGTGACGGATTATTAGATCCAGTCATCGGTCGTGATAAAGAAAT
CCAACAAACTGCAGAAGTCTTAAGTAGACGCACTAAAAACAATCCTATCCTAGTCGGAGAAGCTGGAGTTGGTAAAACTG
CGATTGTCGAAGGTTTAGCGCAAGCAATCGTTGAAGGGAACGTACCTGCAGCAATCAAAGATAAAGAAATTATATCTATA
GATATTTCATCGCTTGAAGCTGGAACGCAATATCGTGGCGCCTTTGAAGAAAACATCCAAAAATTAGTTGAAGGCGTTAA
ATCATCACAAAATGCTGTGCTCTTCTTTGACGAAATTCACCAAATCATCGGTTCCGGCGCAACAGGAAGTGATTCCGGTA
GTAAAGGGTTATCTGATATTTTAAAACCAGCATTAAGTCGTGGTGAAATTTCAATTATAGGCGCAACGACTCAAGATGAA
TATCGCAATAATATCATGAAAGACGCTGCATTAACACGTCGTTTTAACGAAGTACTGGTTAACGAACCAAGCGCAAGAGA
TACGGTTGAAATTTTAAAAGGAATTCGCGAAAAATTTGAAACACACCATCAAGTCAAATTACCTGATGACGTATTAAAGG
CATGTGTAGACTTATCCATTCAATATATTCCACAACGCTTATTACCTGACAAAGCAATCGATGTATTAGATATTACAGCT
GCACATTTATCTGCACAAAGCCCTGCTATTGATAAAGTCGCGACTGAAAAACGTATTTCTGAATTGGAACATGATAAGCG
TAAAGCTGTAAGTGCTGAAGAATATAAAAAAGCAGATGACATTCAAAATGAAATTAAATCTCTACAAGATAAATTAGAAA
ACAGTAATGGTGAACATACTGCAGTAGCAACGGTGCATGATATTTCTGATACCATTCAACGATTAACTGGTATTCCTGTA
TCTCAAATGGATGCCAATGACATTGAACGTTTAAAAAATATTTCTAGTCGTTTAAGAAGTAAAATCATCGGTCAAGATAA
AGCTGTAGAAATGGTTTCTCGTGCCATTCGTCGTAATCGAGCTGGTTTTGATGATGGCAATCGCCCAATTGGTAGCTTCC
TATTTGTCGGACCTACTGGTGTTGGTAAAACAGAGCTTGCCAAACAGTTAGCCATTGATTTATTTGGTAATAAAGAGGCA
CTGATTCGACTTGATATGAGTGAATATAGTGATACTACTGCTGTTTCTAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGACGATAATTCAAATACATTAACTGAAAAAGTACGACGCAATCCATATTCAGTCATTCTATTTGATGAAATTGAAA
AGGCTAATCCACAAATATTAACATTATTACTACAAGTGATGGATGATGGTAATTTAACAGATGGTCAAGGTAACGTCATC
AACTTTAAAAACACAATCATTATTTGTACGTCAAACGCTGGTTTTGGTAACGGTACAGACCAAGAATACGATGACATTAT
GCAAGAAATGAAAAAATTCTTCCGCCCTGAATTTCTTAACCGCTTCAATGGTATTGTGGAATTCTTACACCTAGATAAAG
AGTCACTACAAGAAATCATTAATTTATTGTTGGATGATGTCCAAGTAACATTAGATAAAAAAGGTATTACGATGAATGTC
TCTCAAGATGCAAAAGATTGGTTAATTGAAGAGGGATATGATGAAGAGTTAGGCGCACGCCCATTAAGACGCATTGTTGA
ACAACAAGTGCGTGACAAAATAACAGATTATTATTTAGATCATACAGACGTTAAACATGTGGATTTAGATATCGAAGACA
ACGAATTAGTCGTCAAAGGTAAATCATGA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

• AAA lid domain (AAA_lid_9) (265-363)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	47.745	91.595	0.437
clpC	Lactococcus lactis subsp. cremoris KW2	46.203	90.028	0.416
clpE	Streptococcus pneumoniae Rx1	47.326	87.892	0.416
clpE	Streptococcus pneumoniae D39	47.326	87.892	0.416
clpE	Streptococcus pneumoniae R6	47.326	87.892	0.416
clpE	Streptococcus pneumoniae TIGR4	47.326	87.892	0.416
clpC	Bacillus subtilis subsp. subtilis str. 168	44.037	93.162	0.41
clpC	Streptococcus thermophilus LMD-9	44.8	89.031	0.399
clpC	Streptococcus thermophilus LMG 18311	44.64	89.031	0.397
clpC	Streptococcus pneumoniae TIGR4	43.61	89.174	0.389
clpC	Streptococcus pneumoniae D39	43.78	88.177	0.386
clpC	Streptococcus pneumoniae Rx1	43.78	88.177	0.386
clpC	Streptococcus mutans UA159	43.902	87.607	0.385
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.215	88.746	0.375