Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   DQL75_RS06880 Genome accession   NZ_LS483317
Coordinates   1343246..1345255 (+) Length   669 a.a.
NCBI ID   WP_111762238.1    Uniprot ID   -
Organism   Staphylococcus aureus strain NCTC5663     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1338246..1350255
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL75_RS06865 (NCTC5663_01305) - 1339429..1339794 (+) 366 WP_000282388.1 RicAFT regulatory complex protein RicA family protein -
  DQL75_RS06870 (NCTC5663_01306) thiW 1339821..1340312 (+) 492 WP_000842277.1 energy coupling factor transporter S component ThiW -
  DQL75_RS06875 (NCTC5663_01307) hexA 1340615..1343233 (+) 2619 WP_111762237.1 DNA mismatch repair protein MutS Machinery gene
  DQL75_RS06880 (NCTC5663_01308) hexB 1343246..1345255 (+) 2010 WP_111762238.1 DNA mismatch repair endonuclease MutL Machinery gene
  DQL75_RS06885 (NCTC5663_01309) - 1345261..1345803 (+) 543 WP_001072706.1 glycerol-3-phosphate responsive antiterminator -
  DQL75_RS06890 (NCTC5663_01310) - 1346278..1347096 (+) 819 WP_001103747.1 MIP/aquaporin family protein -
  DQL75_RS06895 (NCTC5663_01311) glpK 1347226..1348722 (+) 1497 WP_000417379.1 glycerol kinase GlpK -

Sequence

Protein


Download         Length: 669 a.a.        Molecular weight: 76966.26 Da        Isoelectric Point: 5.1010

>NTDB_id=1016632 DQL75_RS06880 WP_111762238.1 1343246..1345255(+) (hexB) [Staphylococcus aureus strain NCTC5663]
MGKIKELQTSLANKIAAGEVVERPSSVVKELLENAIDAGATEISIEVEESGVQSIRVVDNGSGIEAEDLGLVFHRHATSK
LDQDEDLFHIRTLGFRGEALASISSVAKVTLKTCTDNANGNEIYVENGEILNHKPAKAKKGTDILVESLFYNTPARLKYI
KSLYTELGKITDIVNRMAMSHPDIRIALISDGKTMLSTNGSGRTNEVMAEIYGMKVARDLVHISGDTSDYHIEGFVAKPE
HSRSNKHYISIFINGRYIKNFMLNKAILEGYHTLLTIGRFPICYINIEMDPILVDVNVHPTKLEVRLSKEEQLYQLIVSK
IQEAFKDRILIPKNNLDYVPKKNKVLHSFEQQKIEFEQRQNTENNQEKTFSSEESNRKPFMAENQNDEIVIKEDSYNPFV
TKTSESLIADDESSGYNNTREKDEDYFKKQQEILQEMDQTFESNDDISVQNYENKTSDDYYDVNDIKGTKSKDPKRRIPY
MEIVGQVHGTYIIAQNEFGMYMIDQHAAQERIKYEYFRDKIGEVTNEVQDLLIPLTFHFSKDEQLVIDQYKNELQQVGIM
LEHFGGHDYIVSSYPVWFPKDEVEEIIKDMIELILEEKKVDIKKLREDVAIMMSCKKSIKANHYLQKHEMSDLIDQLREA
EDPFTCPHGRPIIINFSKYELEKLFKRVM

Nucleotide


Download         Length: 2010 bp        

>NTDB_id=1016632 DQL75_RS06880 WP_111762238.1 1343246..1345255(+) (hexB) [Staphylococcus aureus strain NCTC5663]
ATGGGGAAAATTAAAGAACTCCAAACCTCATTAGCAAATAAAATCGCAGCAGGTGAAGTAGTTGAAAGACCGAGTTCTGT
TGTGAAAGAACTGTTGGAAAATGCTATAGATGCAGGCGCTACAGAAATAAGCATTGAAGTAGAGGAATCTGGCGTCCAAT
CTATTCGCGTAGTCGATAATGGAAGCGGAATTGAAGCGGAAGACTTAGGATTAGTATTTCATAGACATGCGACTAGTAAA
TTAGACCAAGATGAAGATTTATTTCATATTAGGACATTAGGATTCCGTGGTGAAGCACTAGCCAGTATTTCATCAGTTGC
AAAAGTAACATTGAAGACTTGCACGGATAATGCTAATGGAAATGAAATATATGTAGAAAATGGTGAAATATTAAATCATA
AGCCTGCAAAAGCGAAAAAAGGAACAGATATTCTTGTAGAATCATTATTTTATAATACACCAGCACGTTTAAAATATATT
AAAAGTTTATACACTGAACTAGGTAAAATAACAGATATTGTCAACAGAATGGCAATGAGCCATCCGGACATTCGAATAGC
GCTCATTTCAGATGGCAAAACAATGTTAAGTACAAATGGTTCAGGACGAACTAATGAAGTGATGGCAGAGATTTATGGGA
TGAAAGTTGCACGAGATTTAGTACATATATCTGGAGATACAAGTGATTATCACATTGAAGGTTTTGTTGCAAAGCCTGAA
CATTCTAGAAGTAATAAGCACTATATTTCTATTTTTATTAATGGACGATACATTAAAAACTTTATGTTAAATAAAGCGAT
TTTAGAAGGCTATCATACACTCTTAACAATAGGTAGGTTTCCGATTTGTTATATTAATATTGAAATGGATCCAATCTTAG
TAGACGTAAATGTTCATCCAACAAAACTAGAAGTGCGTTTATCAAAAGAAGAGCAACTATATCAATTGATAGTGAGCAAA
ATACAAGAAGCATTTAAAGACCGTATATTAATTCCTAAAAATAACTTGGATTATGTGCCGAAAAAAAATAAAGTGTTACA
TTCATTCGAACAACAAAAAATCGAATTTGAACAAAGACAAAACACAGAGAATAACCAAGAGAAGACGTTTTCATCTGAAG
AAAGTAACCGTAAGCCATTTATGGCAGAAAATCAAAACGATGAGATAGTTATAAAAGAAGATTCATATAATCCATTTGTA
ACGAAAACATCTGAAAGTTTAATAGCTGATGATGAATCTTCCGGTTATAATAATACACGTGAAAAAGATGAAGACTACTT
CAAAAAACAACAAGAAATTTTACAAGAAATGGATCAAACATTTGAGTCAAATGACGATATATCTGTGCAAAATTATGAGA
ATAAAACGTCTGATGATTATTATGATGTAAACGATATTAAAGGAACAAAAAGTAAAGACCCTAAACGAAGAATTCCATAT
ATGGAAATTGTTGGCCAAGTACATGGAACGTATATTATTGCTCAAAATGAATTTGGCATGTACATGATTGACCAGCATGC
AGCTCAAGAAAGAATAAAATATGAATATTTTCGAGATAAAATAGGTGAAGTTACCAATGAAGTACAAGATTTATTAATCC
CGTTAACATTTCATTTTTCAAAAGATGAACAATTAGTCATTGATCAATATAAAAATGAGCTTCAACAAGTAGGTATCATG
TTAGAACATTTTGGTGGTCATGATTATATTGTAAGTAGCTATCCAGTTTGGTTCCCTAAAGATGAAGTAGAAGAAATTAT
TAAAGATATGATTGAGCTAATTTTGGAAGAGAAAAAAGTAGATATCAAAAAATTACGTGAAGATGTAGCAATCATGATGT
CATGTAAAAAATCTATTAAAGCGAATCATTATTTACAAAAACATGAAATGTCTGATTTAATTGATCAATTAAGAGAAGCG
GAAGATCCATTTACATGTCCACATGGTCGTCCAATTATCATTAATTTTTCAAAATACGAATTAGAAAAATTATTTAAGCG
TGTGATGTAG

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(483-625)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-118)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-325)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

40.68

100

0.411