Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   DQM39_RS06235 Genome accession   NZ_LS483298
Coordinates   1170173..1170649 (-) Length   158 a.a.
NCBI ID   WP_002984880.1    Uniprot ID   A0A0H2UU18
Organism   Streptococcus pyogenes strain NCTC8225     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1165173..1175649
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM39_RS06220 (NCTC8225_01250) fbp54 1165985..1167637 (+) 1653 WP_002991968.1 Rqc2 family fibronectin-binding protein Fbp54 -
  DQM39_RS06225 (NCTC8225_01251) - 1167697..1168944 (-) 1248 WP_002984878.1 tetratricopeptide repeat protein -
  DQM39_RS06230 (NCTC8225_01252) - 1168934..1170115 (-) 1182 WP_111680866.1 AI-2E family transporter -
  DQM39_RS06235 (NCTC8225_01253) mutX 1170173..1170649 (-) 477 WP_002984880.1 NUDIX hydrolase Machinery gene
  DQM39_RS06240 (NCTC8225_01254) rfbB 1170870..1171910 (-) 1041 WP_002984881.1 dTDP-glucose 4,6-dehydratase -
  DQM39_RS06245 (NCTC8225_01255) - 1172154..1172747 (-) 594 WP_002984882.1 dTDP-4-dehydrorhamnose 3,5-epimerase family protein -
  DQM39_RS06250 (NCTC8225_01256) rfbA 1172747..1173616 (-) 870 WP_002984885.1 glucose-1-phosphate thymidylyltransferase RfbA -
  DQM39_RS06255 (NCTC8225_01258) - 1173783..1174916 (-) 1134 WP_002987482.1 ISAs1-like element IS1548 family transposase -

Sequence

Protein


Download         Length: 158 a.a.        Molecular weight: 18462.68 Da        Isoelectric Point: 4.3268

>NTDB_id=1015592 DQM39_RS06235 WP_002984880.1 1170173..1170649(-) (mutX) [Streptococcus pyogenes strain NCTC8225]
MTQLATICYIDNGDSLLLLHRNKKENDVHKGKWISVGGKLEAGETPDECARREILEETHLTVTEMAFKGIITFPEFTPGH
DWYTYVFKVTGFEGDLISDEESREGTLEWVPYDQVLEKPTWEGDYDIFKWILEDRPFFSAKFTYDQNNQLMDKSVTFY

Nucleotide


Download         Length: 477 bp        

>NTDB_id=1015592 DQM39_RS06235 WP_002984880.1 1170173..1170649(-) (mutX) [Streptococcus pyogenes strain NCTC8225]
ATGACTCAATTAGCAACCATTTGTTACATTGATAATGGCGATTCTTTGCTATTATTACACCGCAATAAAAAAGAAAATGA
TGTCCACAAAGGCAAGTGGATTTCAGTTGGGGGTAAGCTCGAGGCTGGTGAGACCCCAGATGAGTGTGCCCGTCGTGAGA
TTTTAGAGGAAACCCATTTGACTGTTACAGAGATGGCCTTTAAAGGAATCATTACTTTTCCAGAATTTACCCCTGGTCAT
GACTGGTATACCTATGTTTTTAAAGTAACAGGATTTGAAGGAGACCTCATTTCCGATGAAGAGTCACGAGAAGGAACCTT
GGAATGGGTACCTTACGATCAAGTGTTGGAAAAGCCAACTTGGGAAGGTGATTATGACATTTTTAAATGGATTTTAGAAG
ACCGTCCTTTTTTCTCTGCCAAATTTACCTATGACCAAAACAACCAACTCATGGATAAATCTGTGACCTTTTATTGA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(2-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UU18

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

70.253

100

0.703