Detailed information NTG1013043

Bioinformatically predicted

Overview

• Name: covS
• Type: Regulator
• Locus tag: ABQ274_RS01230
• Genome accession: NZ_CP159281
• Coordinates: 238694..240169 (+)
• Length: 491 a.a.
• NCBI ID: WP_023164352.1
• Uniprot ID: -
• Organism: Lactococcus lactis strain FNZ339
• Function: repress the expression of comX (predicted from homology) Competence regulation

Genomic Context

Location: 233694..245169

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABQ274_RS01195 (ABQ274_01195)	-	233954..234790 (+)	837	WP_023164354.1	metallophosphoesterase	-
ABQ274_RS01200 (ABQ274_01200)	-	234884..235381 (+)	498	WP_226898137.1	CHAP domain-containing protein	-
ABQ274_RS01205 (ABQ274_01205)	-	235867..236229 (+)	363	WP_010906050.1	TIGR02328 family protein	-
ABQ274_RS01210 (ABQ274_01210)	-	236311..236775 (+)	465	WP_003130761.1	hypothetical protein	-
ABQ274_RS01215 (ABQ274_01215)	-	236931..237176 (+)	246	WP_003130760.1	type B 50S ribosomal protein L31	-
ABQ274_RS01220 (ABQ274_01220)	-	237307..237837 (+)	531	WP_023164353.1	DUF177 domain-containing protein	-
ABQ274_RS01225 (ABQ274_01225)	covR	237993..238685 (+)	693	WP_003130756.1	response regulator transcription factor	Regulator
ABQ274_RS01230 (ABQ274_01230)	covS	238694..240169 (+)	1476	WP_023164352.1	HAMP domain-containing histidine kinase	Regulator
ABQ274_RS01235 (ABQ274_01235)	-	240352..241593 (+)	1242	WP_353727382.1	ammonium transporter	-
ABQ274_RS01240 (ABQ274_01240)	-	241725..242066 (+)	342	WP_010906046.1	P-II family nitrogen regulator	-
ABQ274_RS01245 (ABQ274_01245)	murD	242558..243910 (+)	1353	WP_003130748.1	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	-

Sequence

Protein

• Length: 491 a.a.
• Molecular weight: 56241.11 Da
• Isoelectric Point: 4.8253

>NTDB_id=1013043 ABQ274_RS01230 WP_023164352.1 238694..240169(+) (covS) [Lactococcus lactis strain FNZ339]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQQLLTRSMDSVEEVLEKADAPL
NSSNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRHTFGFQNQANNEMKEIRGENPGYLVQRKII
SKSTGQVVGYLQAFYDTTTYHRISNLLLIVLLILEIVALIVAQLIGYFMANYFMKPLEKLYQGMQEMANDPTNDFEPIEI
QSGDEIEELAHVYNDMMLKMKTYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLSLARLENVDLSSEELDCDVGKVCNRALKNFQLLHDDFEIVLDNRLIYPTHARISENHFEQGLRILLDNAAKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGISEEDINHLFERFFRADKARNREIGGTGLGLSILARLAENYQGEIEVNSELGLG
STFTLKFPKIK

Nucleotide

• Length: 1476 bp

>NTDB_id=1013043 ABQ274_RS01230 WP_023164352.1 238694..240169(+) (covS) [Lactococcus lactis strain FNZ339]
ATGAAAAAATTATTTACTTTCAATAAGAAAAAAGAGACGGTAGAGGAAAGTTCGGCTAAGCGGTCTATCATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTTTGTTTGCTACTTTGACTTATCAATTGACAATCAGTTCTT
TTATTAAAGAAGAACAACAATTATTAACTCGCTCTATGGATAGTGTTGAGGAAGTCTTAGAAAAAGCAGATGCTCCTTTG
AATTCATCGAATTTGAACACATATATTGAAGCGACATCAAAGATTCAAAATGGTGAGTCTGAAGGAATGAGTTTGGGTAG
TATCATTGGGACACGGAAAGCATTTTATATTTATGACTTAAATCATAAATTATTGTATTCAACGAATCGACATACTTTTG
GTTTTCAGAATCAGGCTAATAATGAAATGAAAGAGATTCGGGGAGAAAATCCAGGTTATTTAGTTCAGAGAAAAATTATT
TCTAAGTCAACAGGACAAGTTGTGGGATACTTACAGGCTTTTTATGATACGACGACTTATCATCGAATTTCTAATCTTCT
TTTGATTGTCTTGTTAATTTTAGAAATTGTTGCCTTGATTGTCGCTCAGTTGATTGGTTATTTCATGGCTAATTACTTTA
TGAAACCATTGGAAAAACTTTATCAGGGCATGCAAGAAATGGCAAATGATCCAACAAATGATTTTGAACCGATTGAAATT
CAAAGTGGAGATGAAATCGAAGAGTTGGCTCATGTTTACAATGATATGATGTTGAAGATGAAGACATATCTTGAACAGCA
AAATCGCTTTGTTTCTGATGTTTCTCATGAATTAAGAACACCTTTAGCTGTCTTGGATGGACATATTAACTTGTTGAATC
GATGGGGGAAAAATGATCCAGAAGTATTAGATGAATCTTTGCAGGCAAGTTTAGATGAAGTTGATCGAATGAAGAAAATG
CTTGAGGAGATGTTGTCTCTTGCTCGCCTTGAAAATGTTGACTTATCAAGTGAAGAACTGGATTGTGATGTTGGAAAAGT
TTGTAATCGGGCCCTTAAGAATTTTCAGCTTTTGCATGATGATTTTGAAATAGTGCTTGATAACCGGCTTATTTATCCCA
CTCATGCGCGAATTTCAGAAAATCATTTTGAACAAGGTTTACGAATTCTGTTAGATAATGCTGCTAAATACTCTCCTGAT
GATCGTAAAGAAATCGTGATTACTGTTTCTGAGGATGAACAGTTTGTCATTACGAGTGTATCTGACAAAGGAATTGGAAT
TTCAGAAGAAGATATTAATCATCTTTTTGAGCGTTTCTTTAGAGCGGACAAGGCTCGCAATCGAGAAATTGGTGGAACTG
GTTTAGGTTTATCAATTTTAGCTCGATTGGCAGAAAATTATCAAGGGGAAATTGAGGTAAATTCAGAACTGGGTCTTGGT
TCAACTTTTACACTAAAATTCCCGAAAATAAAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (380-489)

• ArlS sensor domain (ArlS_N) (54-185)

• His Kinase A (phospho-acceptor) domain (HisKA) (267-332)

• HAMP domain (HAMP) (208-257)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covS	Lactococcus lactis subsp. lactis strain DGCC12653	99.593	100	0.996