Detailed information NTG0101263

Bioinformatically predicted

Overview

• Name: comB4
• Type: Machinery gene
• Locus tag: HPOKI154_RS02470
• Genome accession: NZ_CP006823
• Coordinates: 504728..507310 (-)
• Length: 860 a.a.
• NCBI ID: WP_025222676.1
• Uniprot ID: -
• Organism: Helicobacter pylori oki154
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 499728..512310

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HPOKI154_RS02450 (HPOKI154_02565)	comB10	500625..501827 (-)	1203	WP_025366790.1	DNA type IV secretion system protein ComB10	Machinery gene
HPOKI154_RS02455 (HPOKI154_02570)	-	501824..503491 (-)	1668	WP_025366791.1	TrbG/VirB9 family P-type conjugative transfer protein	-
HPOKI154_RS02460 (HPOKI154_02575)	-	503488..504604 (-)	1117	Protein_483	VirB8/TrbF family protein	-
HPOKI154_RS02465 (HPOKI154_02580)	-	504597..504731 (-)	135	WP_000738749.1	hypothetical protein	-
HPOKI154_RS02470 (HPOKI154_02585)	comB4	504728..507310 (-)	2583	WP_025222676.1	VirB4 family type IV secretion/conjugal transfer ATPase	Machinery gene
HPOKI154_RS02475 (HPOKI154_02590)	-	507310..507546 (-)	237	WP_001183709.1	hypothetical protein	-
HPOKI154_RS02480 (HPOKI154_02595)	comB3	507557..507820 (-)	264	WP_001177715.1	hypothetical protein	Machinery gene
HPOKI154_RS02485 (HPOKI154_02600)	comB2	507831..508115 (-)	285	WP_000736106.1	TrbC/VirB2 family protein	Machinery gene
HPOKI154_RS02490 (HPOKI154_02605)	-	508112..508591 (-)	480	WP_025222677.1	hypothetical protein	-
HPOKI154_RS02495 (HPOKI154_02610)	-	508695..509483 (-)	789	WP_025222678.1	hypothetical protein	-
HPOKI154_RS02500	-	509538..510308 (+)	771	Protein_491	DNA cytosine methyltransferase	-
HPOKI154_RS02505	-	510301..510567 (+)	267	Protein_492	restriction endonuclease	-
HPOKI154_RS02510	-	510768..511253 (+)	486	Protein_493	restriction endonuclease	-

Sequence

Protein

• Length: 860 a.a.
• Molecular weight: 98978.98 Da
• Isoelectric Point: 8.5615

>NTDB_id=101263 HPOKI154_RS02470 WP_025222676.1 504728..507310(-) (comB4) [Helicobacter pylori oki154]
MFENALKYCKEKAIDLLTGFVPKTYSMTEECNILGLYDDTFIITKQENLVAIMSLQGLSYSSLMQKDLEGYFDTRQNVLN
TISKDIQLRIVAKRRKEFINQSPNIDNPYAKAIITQFESKEIYKTEYFLVFESITSNVKSFFEKKKLEMTTSINEELEES
SKENKQENENSSNETYSNTSSKKDKKNKFKKKTTFSATSKRALLIQTIERVKNALREFKPTLLNSKEVLNFYAEYINGKY
IAFNPKLKRLSDSYITSNIHFKKDYFIIEFQNQSTFCACVGIKNYESEEISSLPISTLLHTQIELDLIFHIRSLGQFESL
NFLKTKKKLTLSKIVKNDIDDYIELVQANRLSLQECALNLVLRAKSKAKLDKSLKEILSLLNNAGLGSVTETIGLKPSYF
SFFPNNANINPRMRNQTSQVIASLILFEKNNTGFRANSWGDMPLSVFKNLDHSPYLFNFHNQEVKHKGVLAHNVARVVGH
TMIIGATGAGKTTLISYLMMSALKYPNIDILALDRLNGLYSFTKYFDGIYNEGESFHINPFSLEDSASNRAFLLHFYAQM
AKVDSYDKHNDKIEDRTALLNAIDTMYRNYNDEVKQAKFSNQELPLPFDLKEFVNSIVKTNTNILDSSFEDYLKSSLFSS
RMDSLDFKTRISTINTDSILHNDDDAGLLAYYVFHKIIDRALRINRGFLCFIDEFKSYAQNEMMNKKINEIITQARKANG
VIVLALQDINQLSEVRNAQSFIKNMGQLILYPQRNIDTKDLNDKFGIRLSDTEKHFLENTAVNEYKVLLKNMNDGSSNII
DVSLSSLGNYLQIFSSNSSMVEHIENLIKHYPTTWKEVFVNNTYQKFDDKKHLEKVLCPT

Nucleotide

• Length: 2583 bp

>NTDB_id=101263 HPOKI154_RS02470 WP_025222676.1 504728..507310(-) (comB4) [Helicobacter pylori oki154]
ATGTTTGAAAACGCTCTTAAATATTGTAAAGAAAAAGCCATAGACCTTTTAACAGGTTTTGTTCCAAAAACCTATTCTAT
GACAGAGGAATGCAATATTTTAGGCTTGTATGATGATACTTTCATCATCACTAAACAAGAAAATTTAGTCGCTATTATGT
CTTTACAAGGACTAAGTTATTCAAGCTTAATGCAAAAAGATTTGGAGGGCTATTTTGATACAAGACAAAATGTTCTAAAC
ACCATTAGTAAAGACATTCAATTAAGGATTGTCGCTAAAAGGCGTAAAGAATTTATCAACCAAAGCCCAAATATTGATAA
CCCATACGCAAAAGCCATTATCACGCAATTTGAGAGCAAGGAAATCTACAAAACAGAGTATTTTTTAGTGTTTGAGAGCA
TTACTTCTAATGTCAAATCTTTCTTTGAGAAAAAGAAATTAGAAATGACTACTTCAATCAATGAAGAATTAGAAGAAAGC
TCTAAAGAGAATAAACAAGAGAATGAAAATAGCTCCAATGAGACCTATTCAAATACAAGCTCTAAAAAAGACAAGAAAAA
CAAGTTCAAAAAAAAGACAACCTTTAGCGCCACAAGTAAAAGAGCCTTACTCATTCAAACCATAGAAAGAGTGAAAAACG
CATTAAGGGAGTTTAAACCCACTCTTTTAAATTCTAAAGAAGTGTTGAATTTTTATGCAGAATATATCAATGGCAAATAC
ATCGCCTTTAATCCTAAATTAAAGCGACTAAGCGATAGCTATATCACTAGTAATATCCATTTTAAAAAAGATTATTTCAT
CATTGAATTTCAAAATCAAAGCACTTTTTGTGCGTGTGTGGGGATTAAAAACTATGAGAGTGAAGAAATTTCTTCACTCC
CCATTTCCACCCTTTTACACACTCAAATTGAATTAGATTTAATCTTTCATATCCGCTCTTTAGGGCAATTTGAAAGCTTG
AATTTTTTAAAAACCAAGAAAAAGCTCACGCTTTCTAAAATCGTTAAAAATGATATTGATGATTATATAGAATTGGTGCA
AGCCAATCGTTTGAGTTTGCAAGAGTGTGCCTTAAACTTAGTTTTAAGAGCTAAAAGTAAAGCAAAACTAGATAAGTCTT
TAAAAGAGATTTTATCTTTACTCAATAACGCTGGACTAGGCAGTGTTACAGAAACCATAGGGCTAAAACCCTCTTATTTT
TCTTTTTTTCCTAATAACGCCAATATCAATCCTAGAATGAGAAATCAAACTTCCCAAGTGATTGCCTCTTTAATCTTGTT
TGAGAAAAATAATACAGGTTTTAGGGCAAATTCATGGGGGGATATGCCTTTATCTGTTTTCAAGAACTTAGATCATAGCC
CTTATTTGTTTAACTTCCACAACCAAGAAGTCAAACATAAAGGCGTGTTAGCGCATAATGTGGCACGAGTGGTAGGACAT
ACCATGATTATTGGCGCAACAGGAGCTGGTAAAACCACGCTCATTAGCTATTTGATGATGAGTGCTTTAAAATACCCTAA
CATTGACATTCTAGCTCTTGATAGATTAAATGGCTTGTATTCTTTTACCAAGTATTTTGATGGGATTTATAATGAAGGCG
AAAGCTTTCATATCAATCCTTTTTCATTAGAAGATAGTGCAAGTAATAGAGCCTTTTTATTGCATTTTTATGCCCAAATG
GCAAAAGTAGATAGCTATGACAAACATAATGATAAGATAGAAGATAGAACAGCCCTTTTAAACGCTATTGATACCATGTA
TAGAAATTATAACGATGAAGTCAAACAAGCCAAATTTAGTAACCAAGAATTACCACTCCCTTTTGATTTAAAAGAGTTTG
TCAATTCCATTGTTAAAACCAATACAAACATTTTAGATAGCAGTTTTGAAGACTATTTAAAATCTTCTTTATTTTCTAGC
CGAATGGATAGCCTAGATTTTAAAACTCGTATTAGCACCATAAATACTGATAGCATTTTACACAATGATGATGACGCTGG
GCTTTTAGCTTATTATGTGTTTCATAAGATAATTGATAGAGCTTTGAGAATCAATCGTGGGTTTTTGTGTTTTATTGATG
AGTTTAAATCTTACGCTCAAAATGAAATGATGAATAAAAAAATCAATGAAATCATCACGCAAGCTAGAAAGGCTAATGGG
GTGATTGTTTTAGCCTTACAAGATATTAACCAGCTTAGTGAAGTGAGAAACGCTCAAAGCTTTATTAAAAATATGGGGCA
ATTAATTTTGTATCCCCAAAGAAATATTGATACCAAAGATTTAAACGATAAATTTGGCATTAGACTAAGCGATACAGAAA
AACATTTTTTAGAAAACACCGCCGTTAATGAATACAAAGTCTTACTCAAAAACATGAATGATGGCTCATCTAACATTATA
GATGTGAGCCTTAGCTCTTTGGGTAATTACTTACAAATCTTTAGCTCCAATTCTAGCATGGTAGAACATATTGAAAATCT
TATTAAGCATTACCCTACTACTTGGAAAGAAGTCTTTGTCAATAACACCTATCAAAAATTTGATGACAAAAAACACTTAG
AAAAGGTGCTTTGCCCAACATGA

Domains

Predicted by InterProScan.

• FtsK/SpoIIIE family (FtsK_SpoIIIE) (437-504)

• CagE, TrbE, VirB family, component of type IV transporter system (CagE_TrbE_VirB) (214-412)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB4	Helicobacter pylori 26695	46.968	97.791	0.459