Detailed information NTG1012154

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: H1W81_RS04055
• Genome accession: NZ_LR824002
• Coordinates: 764878..765963 (+)
• Length: 361 a.a.
• NCBI ID: WP_011226304.1
• Uniprot ID: Q5M3H6
• Organism: Streptococcus thermophilus isolate STH_CIRM_67
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 759878..770963

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W81_RS04040 (STHERMO_0878)	amiA	760420..762387 (+)	1968	WP_011225333.1	peptide ABC transporter substrate-binding protein	Regulator
H1W81_RS04045 (STHERMO_0879)	amiC	762449..763942 (+)	1494	WP_011227407.1	ABC transporter permease	Regulator
H1W81_RS04050 (STHERMO_0880)	amiD	763942..764868 (+)	927	WP_002946409.1	oligopeptide ABC transporter permease OppC	Regulator
H1W81_RS04055 (STHERMO_0881)	amiE	764878..765963 (+)	1086	WP_011226304.1	ABC transporter ATP-binding protein	Regulator
H1W81_RS04060 (STHERMO_0882)	-	765956..766885 (+)	930	WP_002951426.1	ATP-binding cassette domain-containing protein	-
H1W81_RS04065 (STHERMO_0883)	-	766935..767720 (-)	786	WP_002951425.1	hypothetical protein	-
H1W81_RS04070 (STHERMO_0884)	-	767732..768430 (-)	699	WP_011226301.1	ABC transporter ATP-binding protein	-
H1W81_RS04075 (STHERMO_0885)	-	768435..768812 (-)	378	WP_011226300.1	GntR family transcriptional regulator	-
H1W81_RS04080 (STHERMO_0886)	-	768995..769789 (+)	795	WP_059257398.1	HAD hydrolase family protein	-
H1W81_RS04085 (STHERMO_0887)	-	769782..770597 (+)	816	WP_011227405.1	Cof-type HAD-IIB family hydrolase	-

Sequence

Protein

• Length: 361 a.a.
• Molecular weight: 39864.62 Da
• Isoelectric Point: 4.7435

>NTDB_id=1012154 H1W81_RS04055 WP_011226304.1 764878..765963(+) (amiE) [Streptococcus thermophilus isolate STH_CIRM_67]
MTENKNVILSARDIVVEFDVRDRVLTAIRGVSLDLVEGEVLALVGESGSGKSVLTKTFTGMLEENGRVASGSIDYRGKDL
TKFKSHQDWAAIRGAKIATIFQDPMTSLNPIKTIGSQIIEVIVKHQGKTAKEAKKMAIDYMDKVGIPDAEKRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLKEEYGFSVIFITHDLGVVASIADKVAVMYAGEIIE
YATVEEIFYEPCHPYTWSLLSSLPQLADDNGKLFSIPGTPPSLYTPVVGDAFALRSDYALQIDFEEKAPQFQVSDTHWAK
TWLLHEDAPKVDKPAVIQNLHEKILANMGFAHLGDEEEGNA

Nucleotide

• Length: 1086 bp

>NTDB_id=1012154 H1W81_RS04055 WP_011226304.1 764878..765963(+) (amiE) [Streptococcus thermophilus isolate STH_CIRM_67]
ATGACAGAAAATAAAAATGTAATATTATCGGCTCGCGATATCGTCGTGGAATTTGACGTTCGTGACCGTGTTTTGACAGC
TATTCGAGGGGTTTCTCTTGATTTAGTTGAAGGTGAAGTTTTAGCCTTGGTTGGTGAGTCTGGTTCAGGAAAATCAGTCT
TGACTAAAACTTTTACAGGGATGCTGGAAGAAAATGGTCGTGTAGCTAGCGGATCTATCGACTACCGTGGCAAAGACTTG
ACTAAATTTAAGAGTCACCAAGATTGGGCAGCTATCCGTGGAGCTAAGATTGCAACTATTTTCCAAGATCCAATGACCAG
TCTTAACCCAATTAAGACTATCGGAAGTCAAATTATTGAAGTTATTGTTAAGCACCAAGGGAAAACAGCCAAGGAAGCTA
AAAAAATGGCAATTGATTACATGGACAAGGTTGGTATTCCAGATGCTGAAAAACGTTTCAATGAATATCCTTTCCAATAC
TCTGGTGGGATGCGTCAACGTATCGTTATTGCCATTGCCTTGGCTTGTCGTCCTGATGTCCTTATCTGTGACGAACCAAC
AACTGCCCTTGATGTGACCATTCAAGCTCAAATCATTGACCTCTTGAAATCACTCAAAGAGGAGTATGGTTTCTCGGTCA
TTTTCATTACCCATGACCTTGGCGTCGTAGCAAGTATCGCGGACAAGGTTGCTGTCATGTATGCTGGCGAAATCATTGAA
TACGCAACTGTTGAGGAAATTTTCTATGAGCCTTGTCATCCATACACGTGGAGCTTGCTTTCAAGTCTGCCACAATTGGC
TGATGATAATGGAAAACTCTTCTCAATTCCAGGGACGCCACCATCACTTTATACACCAGTTGTTGGGGATGCCTTTGCCT
TGCGTTCAGATTATGCTTTGCAGATTGATTTTGAGGAAAAAGCACCACAATTCCAAGTTTCAGATACTCACTGGGCTAAG
ACCTGGCTCTTACATGAGGATGCGCCAAAAGTTGATAAACCTGCGGTTATCCAAAATCTACATGAAAAAATCCTAGCCAA
TATGGGATTTGCACATTTAGGAGATGAGGAGGAAGGCAATGCCTGA

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-300)

3D structure

• AlphaFold DB: Q5M3H6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus thermophilus LMG 18311	100	100	1
amiE	Streptococcus thermophilus LMD-9	100	100	1
amiE	Streptococcus salivarius strain HSISS4	96.953	100	0.97
oppD	Streptococcus mutans UA159	54.441	96.676	0.526