Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrA   Type   Machinery gene
Locus tag   H1W81_RS02620 Genome accession   NZ_LR824002
Coordinates   479151..481976 (+) Length   941 a.a.
NCBI ID   WP_011226545.1    Uniprot ID   Q5M2Q9
Organism   Streptococcus thermophilus isolate STH_CIRM_67     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 474151..486976
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W81_RS09390 (STHERMO_0547) - 474379..474711 (-) 333 WP_011226548.1 hypothetical protein -
  H1W81_RS02590 (STHERMO_0548) rpsF 474930..475220 (+) 291 WP_002951906.1 30S ribosomal protein S6 -
  H1W81_RS02595 (STHERMO_0549) ssb 475232..475750 (+) 519 WP_002951905.1 single-stranded DNA-binding protein Machinery gene
  H1W81_RS02600 (STHERMO_0550) rpsR 475792..476031 (+) 240 WP_002945024.1 30S ribosomal protein S18 -
  H1W81_RS02605 (STHERMO_0551) - 476158..477039 (-) 882 WP_011226547.1 DUF4300 family protein -
  H1W81_RS02610 (STHERMO_0552) - 477156..477827 (-) 672 WP_011226546.1 DUF1129 domain-containing protein -
  H1W81_RS02615 (STHERMO_0553) - 477898..478842 (-) 945 WP_002951901.1 magnesium transporter CorA family protein -
  H1W81_RS02620 (STHERMO_0554) uvrA 479151..481976 (+) 2826 WP_011226545.1 excinuclease ABC subunit UvrA Machinery gene
  H1W81_RS02625 (STHERMO_0555) - 482070..482342 (+) 273 WP_002946573.1 DUF3923 family protein -
  H1W81_RS02630 (STHERMO_0556) - 482504..482695 (+) 192 WP_002946571.1 hypothetical protein -
  H1W81_RS09755 (STHERMO_0557) - 482904..483038 (+) 135 WP_255136107.1 ATP-binding cassette domain-containing protein -
  H1W81_RS09760 (STHERMO_0558) - 483065..483271 (+) 207 WP_260214609.1 ATP-binding cassette domain-containing protein -
  H1W81_RS02640 (STHERMO_0560) - 483427..483834 (+) 408 WP_232087147.1 ABC transporter ATP-binding protein -
  H1W81_RS02645 (STHERMO_0561) - 483879..484307 (+) 429 WP_011226542.1 hypothetical protein -
  H1W81_RS02650 (STHERMO_0562) - 484497..485558 (+) 1062 WP_011226541.1 M24 family metallopeptidase -
  H1W81_RS02655 (STHERMO_0563) - 485577..486032 (+) 456 WP_002951893.1 deoxycytidylate deaminase -
  H1W81_RS02660 (STHERMO_0564) efp 486145..486705 (+) 561 WP_011226539.1 elongation factor P -

Sequence

Protein


Download         Length: 941 a.a.        Molecular weight: 103935.11 Da        Isoelectric Point: 6.0617

>NTDB_id=1012134 H1W81_RS02620 WP_011226545.1 479151..481976(+) (uvrA) [Streptococcus thermophilus isolate STH_CIRM_67]
MQDKLVIRGARAHNLKNIDVEIPRDKLVVVTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGNMEKPDVDSIDGL
SPAISIDQKTTSKNPRSTVGTVTEINDYLRLLYARVGVPYCINGHGAIKSSSVEQIVDEVLALPERTRMQILAPIVRRRK
GQHKAIFERVQKDGYVRVRVDGEIYDVTEVPELSKSKMHNIEVVVDRLVNKEGIRSRLFDSVEAALRLADGYLIVDTMDD
NELLYSEHYSCPVCGFTVPELEPRLFSFNAPFGSCPTCDGLGNKLEVDIDLVIPDPSKTLREGALAPWNPISSNYYPAML
EQAMEQFGVDMDTPFENLKKEEQDLILYGSGDREFHFHYVNDFGRVRDIDIPFEGVVTNINRRYHETNSDFTRNVMRGYM
NELSCPTCHGYRLNEAALSVRVGGEDGLNIGQISELSISDHLQEIDRLELGENEELIARPIIKEIKDRLTFLNNVGLNYL
TLSRMAGTLSGGESQRIRLATQIGSNLSGVLYVLDEPSIGLHQRDNDRLISSLKKMRDLGNTLIVVEHDEDTMREADWLI
DVGPGAGAFGGQIIASGTPEAVARNKKSITGQYLSGAKSIPVPTERRVGNGCFIEVKGASENNLKNVSVKFPLGKLIAVT
GVSGSGKSTLVNSILKKKIAQELNRNSEKPGKHKSVTGIENIERLIDIDQSPIGRTPRSNPATYTGVFDDIRDLFAQTNE
AKIRGYKKGRFSFNVKGGRCEACSGDGIIKIEMHFLPDVYVPCEVCHGTRYNSETLEVRYKGKNIAEILDMTVDDAVDFF
AAIPKIARKVQTIKDVGLGYVTLGQSATTLSGGEAQRMKLASELHKRSTGKSFYILDEPTTGLHTDDIARLLKVLQRFVD
DGNTVLVIEHNLDVIKTADHIIDLGPEGGVGGGTIVATGTPEEVVAVSKSYTGQYLKEKLK

Nucleotide


Download         Length: 2826 bp        

>NTDB_id=1012134 H1W81_RS02620 WP_011226545.1 479151..481976(+) (uvrA) [Streptococcus thermophilus isolate STH_CIRM_67]
ATGCAAGATAAGTTAGTGATTCGCGGAGCAAGAGCTCACAATTTAAAAAATATTGATGTAGAGATTCCTCGTGACAAGCT
CGTCGTCGTGACGGGGTTGTCGGGGTCTGGTAAGTCTTCTTTGGCTTTTGATACAATTTATGCAGAGGGTCAGCGCCGTT
ATGTTGAAAGTCTCTCAGCTTATGCCCGCCAATTCTTGGGAAATATGGAGAAACCTGATGTGGACTCGATTGATGGCTTG
AGTCCTGCCATCTCCATTGATCAGAAAACAACGAGTAAGAACCCTCGTTCGACTGTGGGAACTGTAACGGAGATTAATGA
CTATCTTCGTCTCCTTTATGCGCGTGTGGGTGTGCCTTATTGTATCAATGGGCATGGAGCCATTAAGTCGTCATCAGTGG
AACAGATTGTAGATGAGGTTTTAGCCCTTCCTGAACGGACACGTATGCAGATTTTAGCGCCGATTGTCCGTCGTCGAAAG
GGGCAACACAAGGCGATTTTTGAGCGCGTGCAGAAGGACGGTTATGTTCGTGTTCGTGTGGATGGTGAGATATACGATGT
GACGGAAGTCCCTGAGCTATCCAAGTCGAAGATGCATAATATTGAGGTGGTTGTGGACCGTTTGGTTAATAAGGAAGGTA
TCCGTAGTCGTCTCTTTGACTCAGTCGAGGCAGCGCTACGTTTAGCGGATGGCTACTTGATTGTGGATACTATGGATGAT
AATGAATTGCTCTACTCGGAGCATTATTCTTGTCCAGTTTGTGGTTTTACAGTGCCTGAGTTGGAGCCGCGTCTCTTTTC
CTTCAATGCGCCATTTGGTTCTTGTCCGACCTGTGACGGTTTAGGAAATAAACTAGAAGTTGATATTGATTTGGTCATTC
CTGACCCTAGTAAGACCTTGCGTGAAGGTGCACTAGCGCCTTGGAATCCTATCTCATCCAACTACTATCCTGCCATGCTT
GAGCAGGCCATGGAACAGTTTGGCGTGGATATGGATACGCCATTTGAAAATCTTAAAAAAGAAGAACAAGATTTGATTCT
CTACGGATCTGGTGACCGCGAGTTCCATTTCCATTATGTTAATGATTTTGGTAGGGTGCGTGATATTGACATTCCTTTTG
AAGGGGTTGTGACTAATATCAATCGACGCTATCATGAGACTAACAGTGATTTCACCCGCAATGTCATGCGTGGTTATATG
AATGAACTGTCATGTCCAACTTGTCATGGCTATCGTCTTAACGAAGCAGCACTCTCGGTTCGTGTTGGTGGTGAGGATGG
CTTAAATATTGGTCAAATTTCTGAGCTGTCTATTTCTGATCATCTTCAAGAAATAGATCGCCTTGAATTAGGTGAGAATG
AAGAATTGATTGCCCGTCCAATTATCAAGGAAATCAAGGATCGTCTGACTTTCTTAAACAATGTCGGCCTTAATTACTTG
ACTCTCTCTCGTATGGCCGGAACACTTTCAGGTGGTGAGAGTCAGCGTATCCGTTTGGCGACACAGATTGGCTCCAACCT
TTCTGGAGTCCTTTATGTTTTGGATGAGCCCTCTATAGGTCTTCATCAGCGTGATAATGATCGCTTGATTTCAAGTCTTA
AAAAGATGCGTGATTTGGGCAATACCTTAATTGTGGTGGAGCATGATGAAGATACCATGCGTGAAGCTGACTGGCTTATC
GATGTAGGACCTGGCGCCGGTGCCTTTGGTGGACAAATCATAGCTTCAGGAACCCCAGAAGCAGTTGCTAGAAATAAGAA
ATCAATTACTGGTCAGTACCTGTCAGGTGCTAAATCAATTCCTGTACCGACGGAACGCCGTGTAGGAAACGGCTGTTTTA
TCGAGGTTAAAGGAGCCAGTGAAAATAATCTTAAAAATGTGTCTGTCAAGTTCCCACTTGGAAAATTAATCGCAGTGACA
GGCGTTTCTGGTTCTGGAAAGTCAACTTTGGTTAACAGTATTCTCAAGAAAAAGATTGCCCAAGAGCTTAATCGAAACAG
TGAGAAACCTGGGAAACATAAATCGGTGACTGGAATCGAGAATATCGAGCGTTTGATTGATATTGATCAAAGTCCAATCG
GGCGTACTCCACGTTCCAACCCTGCAACCTACACAGGCGTCTTCGACGATATTCGCGATCTTTTTGCTCAAACCAATGAG
GCCAAGATTCGCGGTTATAAGAAGGGACGTTTCTCTTTCAATGTCAAAGGTGGTCGTTGTGAAGCCTGCTCTGGTGATGG
GATTATCAAGATTGAGATGCACTTCTTGCCTGATGTTTATGTACCTTGTGAGGTTTGCCATGGCACACGCTATAATTCTG
AGACCTTAGAAGTTCGTTATAAAGGGAAGAATATTGCTGAAATTCTGGATATGACAGTTGATGACGCGGTTGATTTCTTT
GCGGCTATCCCTAAGATTGCTCGTAAGGTGCAGACAATCAAGGATGTGGGGCTCGGGTATGTGACTTTGGGGCAATCAGC
AACAACCCTATCAGGTGGTGAGGCACAGCGTATGAAACTGGCTAGTGAACTTCACAAACGCTCTACTGGGAAGTCTTTCT
ACATTCTCGATGAGCCTACGACTGGTCTCCATACAGATGACATTGCTCGTCTCTTGAAGGTGCTTCAGCGTTTTGTGGAC
GATGGTAACACGGTTCTCGTGATTGAGCACAATCTGGATGTTATTAAGACAGCAGACCATATCATTGATTTGGGTCCTGA
AGGTGGTGTTGGTGGAGGTACTATCGTAGCTACAGGGACTCCAGAAGAGGTAGTAGCCGTTTCCAAAAGCTATACAGGAC
AATATTTGAAAGAAAAATTGAAATAA

Domains

Predicted by InterProScan.

ABC transporter (ABC_tran)

(624-860)

UvrA DNA-binding domain (UvrA_DNA-bind)

(288-396)

UvrA interaction domain (UvrA_inter)

(132-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2Q9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrA Streptococcus pneumoniae R6

85

99.894

0.849
  uvrA Streptococcus pneumoniae TIGR4

85

99.894

0.849
  uvrA Streptococcus pneumoniae D39

85

99.894

0.849

Multiple sequence alignment