Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGG   Type   Machinery gene
Locus tag   H1W81_RS02085 Genome accession   NZ_LR824002
Coordinates   382441..382758 (+) Length   105 a.a.
NCBI ID   WP_011226623.1    Uniprot ID   Q5M2G4
Organism   Streptococcus thermophilus isolate STH_CIRM_67     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 377441..387758
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W81_RS02050 (STHERMO_0422) - 378700..379062 (+) 363 WP_011226630.1 DUF1033 family protein -
  H1W81_RS02055 (STHERMO_0423) comGA/cglA/cilD 379143..380084 (+) 942 WP_180484814.1 competence type IV pilus ATPase ComGA Machinery gene
  H1W81_RS02060 (STHERMO_0424) comGB 379966..381066 (+) 1101 WP_375708571.1 competence type IV pilus assembly protein ComGB Machinery gene
  H1W81_RS02065 (STHERMO_0425) comGC 381063..381389 (+) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  H1W81_RS02070 (STHERMO_0426) comGD 381349..381777 (+) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  H1W81_RS02075 (STHERMO_0427) comGE 381749..382042 (+) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  H1W81_RS02080 (STHERMO_0428) comGF 382026..382463 (+) 438 WP_014608742.1 competence type IV pilus minor pilin ComGF Machinery gene
  H1W81_RS02085 (STHERMO_0429) comGG 382441..382758 (+) 318 WP_011226623.1 competence type IV pilus minor pilin ComGG Machinery gene
  H1W81_RS02090 (STHERMO_0430) comGH 382803..383759 (+) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  H1W81_RS02095 (STHERMO_0431) - 383815..385008 (+) 1194 WP_022096898.1 acetate kinase -
  H1W81_RS02100 (STHERMO_0432) - 385257..385454 (+) 198 WP_011681682.1 helix-turn-helix transcriptional regulator -
  H1W81_RS09365 (STHERMO_0434) - 385697..386122 (+) 426 WP_041827107.1 CPBP family intramembrane glutamic endopeptidase -
  H1W81_RS02110 (STHERMO_0435) - 386196..386644 (+) 449 Protein_360 CAAX protease -
  H1W81_RS02115 (STHERMO_0437) - 386747..387409 (+) 663 WP_179971686.1 CPBP family intramembrane glutamic endopeptidase -

Sequence

Protein


Download         Length: 105 a.a.        Molecular weight: 11796.88 Da        Isoelectric Point: 10.6334

>NTDB_id=1012126 H1W81_RS02085 WP_011226623.1 382441..382758(+) (comGG) [Streptococcus thermophilus isolate STH_CIRM_67]
MLLKKQVRGGVLLYALFMAGIFTLLLQAYLERVVASSRQNQAQIVASQSRLMAEMTMDLVDKEAGAFSFSQGTTTYEVKG
KQVIVRVASKGQIKTYRYVKKQDQK

Nucleotide


Download         Length: 318 bp        

>NTDB_id=1012126 H1W81_RS02085 WP_011226623.1 382441..382758(+) (comGG) [Streptococcus thermophilus isolate STH_CIRM_67]
ATGCTTTTGAAAAAACAGGTTAGGGGAGGCGTTCTTCTCTACGCTCTTTTTATGGCTGGCATTTTTACACTCCTTCTTCA
GGCTTATCTGGAACGGGTGGTAGCTAGCTCTAGACAAAACCAAGCGCAAATAGTGGCCAGTCAAAGCCGTCTCATGGCAG
AGATGACTATGGACTTGGTGGATAAGGAAGCAGGTGCTTTTAGTTTTTCTCAGGGGACTACGACTTACGAGGTTAAGGGT
AAGCAAGTGATTGTCAGAGTTGCCAGTAAAGGCCAAATCAAGACCTATCGTTATGTGAAGAAACAAGATCAGAAATAG

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGG Streptococcus mutans UA140

45.455

94.286

0.429
  comGG Streptococcus mutans UA159

45.455

94.286

0.429
  comGG/cglG Streptococcus pneumoniae Rx1

42.222

85.714

0.362
  comGG/cglG Streptococcus pneumoniae D39

42.222

85.714

0.362
  comGG/cglG Streptococcus pneumoniae R6

42.222

85.714

0.362
  comGG/cglG Streptococcus pneumoniae TIGR4

42.222

85.714

0.362

Multiple sequence alignment