Detailed information NTG1011882

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: V5233_RS13830
• Genome accession: NZ_CP158667
• Coordinates: 2754286..2755173 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain BSN25
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2749286..2760173

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V5233_RS13800 (V5233_0013800)	-	2749305..2749397 (+)	93	WP_010956583.1	hypothetical protein	-
V5233_RS13805 (V5233_0013805)	-	2749505..2750002 (-)	498	WP_001065268.1	glutathione peroxidase	-
V5233_RS13810 (V5233_0013810)	-	2750012..2750272 (-)	261	WP_001791974.1	hypothetical protein	-
V5233_RS13815 (V5233_0013815)	-	2750654..2750767 (-)	114	Protein_2683	hypothetical protein	-
V5233_RS13820 (V5233_0013820)	-	2751426..2753426 (-)	2001	WP_000776751.1	ABC transporter permease	-
V5233_RS13825 (V5233_0013825)	-	2753423..2754178 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
V5233_RS13830 (V5233_0013830)	braS	2754286..2755173 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
V5233_RS13835 (V5233_0013835)	braR	2755184..2755849 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
V5233_RS13840 (V5233_0013840)	-	2755875..2756075 (-)	201	WP_000604730.1	hypothetical protein	-
V5233_RS13845 (V5233_0013845)	-	2756273..2757697 (+)	1425	WP_000953755.1	alkaline phosphatase	-
V5233_RS13850 (V5233_0013850)	-	2757757..2757858 (-)	102	WP_000731976.1	SE2200 family small protein	-
V5233_RS13855 (V5233_0013855)	-	2757980..2758435 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
V5233_RS13860 (V5233_0013860)	-	2758680..2759441 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=1011882 V5233_RS13830 WP_000143425.1 2754286..2755173(-) (braS) [Staphylococcus aureus strain BSN25]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1011882 V5233_RS13830 WP_000143425.1 2754286..2755173(-) (braS) [Staphylococcus aureus strain BSN25]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1