Detailed information    

insolico Bioinformatically predicted

Overview

Name   rexA   Type   Machinery gene
Locus tag   H1W94_RS07970 Genome accession   NZ_LR822041
Coordinates   1534259..1537912 (-) Length   1217 a.a.
NCBI ID   WP_011227531.1    Uniprot ID   Q5LY80
Organism   Streptococcus thermophilus isolate STH_CIRM_1122     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1529259..1542912
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W94_RS07950 (STHERMO_1765) proB 1529610..1530413 (-) 804 WP_002948808.1 glutamate 5-kinase -
  H1W94_RS07955 (STHERMO_1766) - 1530534..1532123 (-) 1590 WP_011226516.1 hypothetical protein -
  H1W94_RS07960 (STHERMO_1767) - 1532126..1532858 (-) 733 Protein_1508 ABC transporter ATP-binding protein -
  H1W94_RS07965 (STHERMO_1770) - 1533132..1533865 (+) 734 Protein_1509 DUF554 domain-containing protein -
  H1W94_RS07970 (STHERMO_1772) rexA 1534259..1537912 (-) 3654 WP_011227531.1 helicase-exonuclease AddAB subunit AddA Machinery gene
  H1W94_RS07975 (STHERMO_1773) rexB 1537902..1541222 (-) 3321 WP_011226521.1 ATP-dependent nuclease subunit B Machinery gene
  H1W94_RS10210 (STHERMO_1775) - 1541712..1542363 (-) 652 Protein_1512 hypothetical protein -
  H1W94_RS10215 - 1542416..1542846 (-) 431 Protein_1513 LytTR family DNA-binding domain-containing protein -

Sequence

Protein


Download         Length: 1217 a.a.        Molecular weight: 138351.38 Da        Isoelectric Point: 4.7157

>NTDB_id=1011693 H1W94_RS07970 WP_011227531.1 1534259..1537912(-) (rexA) [Streptococcus thermophilus isolate STH_CIRM_1122]
MLTKAFLSPAEIEERIAQEAASDKDRKLTPEQIEAIYSNGTNILVSASAGSGKTFVMVERILDMIGRGVGIDQLFISTFT
VKAAGELKERLEKRLTKHLGQAETDEERAFLSDQIAKIGTADIGTMDAFTQKLVNQYGYLLGVSPTFRIMTDLAEQTLMK
NEVYADLFNDYMQGKDAQLFQKLVRNFTGHSKTSKAFRDLVYDIYSFSQATADPEKWLCQNLLKGQIEAKPEQAKNELLD
GLKDGLLADFLAFLRDHLGIAQREFAKAKYLNNVSDAIILLEGSLINDQTDMEDLLKQLLTLSGGTGLTNMTRPKDEELK
AYKEAYNKTKNEFVAQLREVDTQLTVLEVLTKHNDDILPMLELLQSFVLDFSDQYLQAKIQENTFEFSDIAHFAIRILEE
NPEVAVSYRDRYHEVMVDEYQDNSHTQERMLELLSNGHNRFMVGDIKQSIYRFRQADPQIFNDKFQLFLENPDAGKLILL
KENFRSQSEVLDATNGVFSHLMDQEIGDILYDKTHMLVAGSQKQKEPHPENETEVLIYNSDESSTSEDEEGPDQAISSGE
ISLVIKEIIKLHEQGVRFEDITLLAPNRNTYLDLMVSFEEHGIPLVPDEYKSSYLESLEVMIMLDTLRAINNPLNDYALV
ALLRSPMFNFNEDDLTRIAVQADKGQFYDKLLAAHTKSGLHPEVVMQGLEAKLTLFTETLADWRDYSKCHSIYDLIWKIY
NDRFYYDYVGGLPRAEQRQANLYALALRANAYEKTGFKGLSRFIGMIDKIIASGNDLEEVTDLVPKNAVSLMTIHKSKGL
EFKYVFVLQMNRKFIGHSKDGLSGKYIINREKGLGIKYLADLKDQINTNLPKLNVVLETLTFQDNRREERRASISEEMRL
LYVAMTRAEKKLYLVGKGSKETLTQQYGTDVENNRLPVALRDQIATYQDWIMALDTAFMRKDLKFTVRFVEDEELTPEAI
GQVEVKAAVDADDLSNNRQTEEIERALTVLESVEKLNHLYAPAIDLPSVRTPSQLKTFYEPIMDTEGVDIMDKKEGVQPL
ETASTFELPDFGQKTKVTGAAVGSATHELMQRLTLSDTVTLQDLTQALSRVSASDQVKARVQLEKLLGFFDTELGKLILA
NRDKLRREAPFAMLAEDPASKEDFVVRGIIDGYLLLEDRIVLFDYKTDHFTHPSELKTRYQGQMSLYAKALSQAYQMEKV
DKYLILLGGKDLEVVEV

Nucleotide


Download         Length: 3654 bp        

>NTDB_id=1011693 H1W94_RS07970 WP_011227531.1 1534259..1537912(-) (rexA) [Streptococcus thermophilus isolate STH_CIRM_1122]
ATGTTGACTAAAGCTTTTTTAAGTCCAGCAGAGATTGAGGAACGTATTGCCCAAGAAGCAGCTTCTGACAAGGATCGCAA
GTTAACACCAGAACAGATTGAAGCTATTTACAGTAATGGTACTAATATTTTGGTATCTGCCTCAGCTGGTTCAGGGAAAA
CCTTTGTCATGGTTGAGCGTATCCTTGATATGATTGGACGTGGCGTTGGTATTGATCAACTCTTTATCTCAACCTTTACG
GTAAAAGCTGCAGGTGAGTTAAAGGAGCGTCTGGAAAAGCGGCTGACAAAGCATTTAGGACAGGCAGAGACGGATGAGGA
GCGGGCATTTCTTTCAGACCAGATTGCCAAGATTGGGACGGCTGATATTGGAACCATGGATGCCTTTACCCAGAAATTGG
TCAATCAGTATGGCTATCTCCTGGGTGTGTCACCTACTTTCCGTATCATGACAGACCTTGCTGAGCAGACGCTTATGAAA
AATGAGGTTTATGCTGATCTCTTCAATGATTACATGCAAGGAAAGGATGCCCAACTTTTTCAAAAATTGGTCCGTAATTT
CACTGGACATAGCAAAACTAGCAAGGCTTTTCGTGATTTAGTTTACGATATTTACAGCTTTTCTCAGGCTACTGCAGATC
CTGAAAAATGGCTATGTCAAAATCTCTTGAAAGGACAGATCGAGGCTAAGCCAGAACAGGCTAAAAATGAGCTTTTAGAC
GGTCTTAAAGATGGCTTGTTGGCTGATTTCCTAGCTTTCTTAAGAGACCATTTAGGTATAGCTCAGCGTGAATTTGCCAA
GGCCAAGTATCTGAATAATGTGTCAGATGCCATTATCCTTCTTGAGGGCTCCTTGATTAATGACCAAACTGATATGGAGG
ACCTCCTCAAACAACTATTGACTCTGTCAGGAGGTACTGGTTTGACCAATATGACCCGTCCTAAAGACGAGGAACTCAAG
GCCTACAAGGAAGCATACAACAAGACCAAAAATGAGTTTGTGGCTCAGTTGCGAGAGGTCGATACTCAGCTCACCGTTCT
GGAGGTTTTGACCAAGCATAATGATGATATCCTACCTATGTTGGAGCTACTTCAGTCCTTTGTACTTGATTTTTCGGATC
AGTATTTACAGGCAAAGATTCAGGAAAATACCTTTGAATTCTCGGATATTGCCCACTTTGCTATCCGTATTTTGGAAGAA
AATCCAGAGGTGGCAGTCAGCTACCGGGACCGTTACCATGAAGTTATGGTGGATGAGTATCAGGACAATAGCCATACTCA
AGAACGAATGTTGGAACTTCTATCTAACGGCCATAACCGATTCATGGTGGGAGATATCAAGCAGTCCATTTATCGTTTCC
GTCAGGCAGACCCTCAGATTTTTAATGATAAGTTTCAGCTTTTCCTTGAAAATCCTGATGCAGGTAAGCTGATTCTCCTT
AAGGAGAACTTTCGTAGTCAATCTGAAGTCCTTGATGCGACAAATGGTGTTTTTAGCCACCTCATGGATCAGGAAATCGG
GGACATCCTATATGACAAGACTCATATGTTGGTAGCAGGTAGTCAGAAGCAAAAAGAGCCCCATCCTGAAAATGAAACTG
AGGTTCTGATTTATAATAGTGATGAATCTAGTACGAGTGAGGATGAAGAAGGTCCTGATCAAGCTATCAGCAGCGGTGAG
ATTTCCTTGGTTATCAAAGAAATTATCAAACTTCATGAGCAGGGTGTACGTTTTGAGGACATCACCCTCCTAGCACCGAA
CCGTAACACCTATCTGGACTTGATGGTAAGTTTCGAGGAACACGGGATTCCCTTGGTTCCTGACGAGTATAAGTCAAGCT
ACCTAGAGTCACTAGAAGTTATGATTATGTTGGACACCCTTCGTGCTATCAATAATCCTCTTAACGATTATGCTCTCGTT
GCTCTCCTTCGTTCACCTATGTTTAACTTCAACGAGGATGACCTGACTCGTATCGCAGTTCAGGCTGACAAAGGCCAATT
CTATGATAAGCTTCTTGCAGCTCATACCAAATCAGGTCTTCATCCGGAAGTTGTGATGCAAGGACTTGAAGCCAAGTTGA
CTCTCTTCACAGAGACTCTGGCAGATTGGCGTGACTACAGTAAGTGTCATTCGATTTATGACCTCATTTGGAAGATTTAC
AACGACCGTTTCTATTATGATTACGTCGGAGGTCTTCCACGAGCTGAGCAACGCCAGGCCAATCTTTATGCCCTTGCCTT
GCGTGCTAATGCTTATGAAAAGACAGGATTTAAGGGGCTTTCTCGTTTTATTGGCATGATTGATAAGATTATTGCTAGCG
GTAACGACCTAGAGGAAGTGACAGATTTGGTTCCCAAAAATGCCGTTAGCCTCATGACCATTCACAAGTCCAAGGGGCTA
GAGTTCAAGTATGTCTTTGTCCTGCAGATGAATCGCAAGTTCATTGGTCACAGCAAGGATGGCCTGAGCGGTAAGTATAT
TATCAATCGTGAAAAAGGGCTTGGTATTAAGTATCTAGCTGACCTCAAAGACCAGATAAACACCAATTTGCCTAAGTTAA
ATGTTGTTCTTGAGACCTTGACCTTCCAGGATAATCGTAGGGAAGAGCGCAGGGCAAGTATTTCAGAAGAGATGCGTCTA
CTCTATGTGGCAATGACACGTGCAGAGAAGAAACTCTACCTAGTTGGTAAGGGAAGTAAGGAAACCTTAACCCAGCAGTA
TGGCACTGATGTCGAAAATAATCGCCTACCAGTGGCTCTACGTGACCAGATTGCTACTTATCAGGATTGGATTATGGCAC
TTGATACTGCTTTTATGAGAAAAGACCTCAAGTTTACTGTTCGCTTTGTTGAGGATGAGGAGTTGACGCCAGAGGCTATT
GGACAGGTTGAAGTCAAGGCAGCAGTAGATGCCGATGATTTATCTAACAATCGTCAGACGGAGGAGATTGAGCGTGCCTT
GACTGTCTTAGAAAGTGTTGAAAAACTCAACCACCTTTATGCACCAGCGATTGACCTACCTTCTGTGCGTACCCCAAGCC
AGCTCAAGACCTTTTACGAACCAATTATGGATACAGAGGGCGTAGATATCATGGATAAGAAAGAGGGAGTGCAACCTCTT
GAGACGGCTAGCACTTTTGAGCTACCAGACTTTGGGCAAAAAACTAAGGTCACTGGAGCTGCAGTTGGTTCAGCAACCCA
TGAACTCATGCAACGCTTGACTCTTTCTGATACAGTGACTCTCCAAGATTTGACTCAGGCACTGAGTCGGGTATCGGCAT
CTGATCAAGTCAAGGCGCGTGTTCAGTTAGAAAAACTTTTAGGCTTCTTTGATACAGAGCTCGGGAAGCTTATTTTGGCC
AACCGTGATAAGTTGCGTCGTGAAGCACCTTTTGCCATGTTGGCAGAAGACCCAGCTAGTAAAGAAGACTTTGTTGTTCG
TGGAATCATTGATGGCTATCTTCTTCTTGAAGACCGTATTGTCCTCTTTGACTACAAGACCGACCACTTCACTCATCCTA
GTGAGCTTAAGACGCGCTACCAAGGGCAAATGAGCCTCTATGCTAAAGCGCTTAGCCAAGCCTATCAAATGGAAAAGGTC
GACAAATATCTTATCCTCTTGGGTGGAAAGGACTTAGAAGTTGTAGAAGTATAA

Domains

Predicted by InterProScan.

UvrD/REP helicase N-terminal domain (UvrD-helicase)

(28-464)

UvrD-like helicase C-terminal domain (UvrD_C)

(478-894)

PD-(D/E)XK nuclease superfamily (PDDEXK_1)

(1059-1198)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5LY80

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  rexA Streptococcus pneumoniae R6

50.612

100

0.509

Multiple sequence alignment