Detailed information NTG1011676

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: H1W94_RS06720
• Genome accession: NZ_LR822041
• Coordinates: 1285774..1286859 (-)
• Length: 361 a.a.
• NCBI ID: WP_011226304.1
• Uniprot ID: Q5M3H6
• Organism: Streptococcus thermophilus isolate STH_CIRM_1122
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1280774..1291859

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W94_RS06690 (STHERMO_1472)	-	1281140..1281955 (-)	816	WP_156703494.1	Cof-type HAD-IIB family hydrolase	-
H1W94_RS06695 (STHERMO_1473)	-	1281948..1282742 (-)	795	WP_059257398.1	HAD hydrolase family protein	-
H1W94_RS06700 (STHERMO_1474)	-	1282925..1283302 (+)	378	WP_011226300.1	GntR family transcriptional regulator	-
H1W94_RS06705 (STHERMO_1475)	-	1283307..1284005 (+)	699	WP_011226301.1	ABC transporter ATP-binding protein	-
H1W94_RS06710 (STHERMO_1476)	-	1284017..1284802 (+)	786	WP_002951425.1	hypothetical protein	-
H1W94_RS06715 (STHERMO_1477)	-	1284852..1285781 (-)	930	WP_002951426.1	ATP-binding cassette domain-containing protein	-
H1W94_RS06720 (STHERMO_1478)	amiE	1285774..1286859 (-)	1086	WP_011226304.1	ABC transporter ATP-binding protein	Regulator
H1W94_RS06725 (STHERMO_1479)	amiD	1286869..1287795 (-)	927	WP_180478549.1	oligopeptide ABC transporter permease OppC	Regulator
H1W94_RS06730 (STHERMO_1480)	amiC	1287795..1289288 (-)	1494	WP_011227407.1	ABC transporter permease	Regulator
H1W94_RS06735 (STHERMO_1481)	amiA	1289350..1291317 (-)	1968	WP_011226784.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 361 a.a.
• Molecular weight: 39864.62 Da
• Isoelectric Point: 4.7435

>NTDB_id=1011676 H1W94_RS06720 WP_011226304.1 1285774..1286859(-) (amiE) [Streptococcus thermophilus isolate STH_CIRM_1122]
MTENKNVILSARDIVVEFDVRDRVLTAIRGVSLDLVEGEVLALVGESGSGKSVLTKTFTGMLEENGRVASGSIDYRGKDL
TKFKSHQDWAAIRGAKIATIFQDPMTSLNPIKTIGSQIIEVIVKHQGKTAKEAKKMAIDYMDKVGIPDAEKRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLKEEYGFSVIFITHDLGVVASIADKVAVMYAGEIIE
YATVEEIFYEPCHPYTWSLLSSLPQLADDNGKLFSIPGTPPSLYTPVVGDAFALRSDYALQIDFEEKAPQFQVSDTHWAK
TWLLHEDAPKVDKPAVIQNLHEKILANMGFAHLGDEEEGNA

Nucleotide

• Length: 1086 bp

>NTDB_id=1011676 H1W94_RS06720 WP_011226304.1 1285774..1286859(-) (amiE) [Streptococcus thermophilus isolate STH_CIRM_1122]
ATGACAGAAAATAAAAATGTAATATTATCGGCTCGCGATATCGTCGTGGAATTTGACGTTCGTGACCGTGTTTTGACAGC
TATTCGAGGGGTTTCTCTTGATTTAGTTGAAGGTGAAGTTTTAGCCTTGGTTGGTGAGTCTGGTTCAGGAAAATCAGTCT
TGACTAAAACTTTTACAGGGATGCTGGAAGAAAATGGTCGTGTAGCTAGCGGATCTATCGACTACCGTGGCAAAGACTTG
ACTAAATTTAAGAGTCACCAAGATTGGGCAGCTATCCGTGGAGCTAAGATTGCAACTATTTTCCAAGATCCAATGACCAG
TCTTAACCCAATTAAGACTATCGGAAGTCAAATTATTGAAGTTATTGTTAAGCACCAAGGGAAAACAGCCAAGGAAGCTA
AAAAAATGGCAATTGATTACATGGACAAGGTTGGTATTCCAGATGCTGAAAAACGTTTCAATGAATATCCTTTCCAATAC
TCTGGTGGGATGCGTCAACGTATCGTTATTGCCATTGCCTTGGCTTGTCGTCCTGATGTCCTTATCTGTGACGAACCAAC
AACTGCCCTTGATGTGACCATTCAAGCTCAAATCATTGACCTCTTGAAATCACTCAAAGAGGAGTATGGTTTCTCGGTCA
TTTTCATTACCCATGACCTTGGCGTCGTAGCAAGTATCGCGGACAAGGTTGCTGTCATGTATGCTGGCGAAATCATTGAA
TACGCAACTGTTGAGGAAATTTTCTATGAGCCTTGTCATCCATACACGTGGAGCTTGCTTTCAAGTCTGCCACAATTGGC
TGATGATAATGGAAAACTCTTCTCAATTCCAGGGACGCCACCATCACTTTATACACCAGTTGTTGGGGATGCCTTTGCCT
TGCGTTCAGATTATGCTTTGCAGATTGATTTTGAGGAAAAAGCACCACAATTCCAAGTTTCAGATACTCACTGGGCTAAG
ACCTGGCTCTTACATGAGGATGCGCCAAAAGTTGATAAACCTGCGGTTATCCAAAATCTACATGAAAAAATCCTAGCCAA
TATGGGATTTGCACATTTAGGAGATGAGGAGGAAGGCAATGCCTGA

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-300)

3D structure

• AlphaFold DB: Q5M3H6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus thermophilus LMG 18311	100	100	1
amiE	Streptococcus thermophilus LMD-9	100	100	1
amiE	Streptococcus salivarius strain HSISS4	96.953	100	0.97
oppD	Streptococcus mutans UA159	54.441	96.676	0.526