Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   H1W80_RS08440 Genome accession   NZ_LR822040
Coordinates   1632253..1632546 (-) Length   97 a.a.
NCBI ID   WP_180473353.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1125     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1627253..1637546
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W80_RS08405 (STHERMO_1897) - 1627655..1628098 (-) 444 WP_180473351.1 CAAX protease -
  H1W80_RS09720 (STHERMO_1898) - 1628172..1628597 (-) 426 WP_232086518.1 CPBP family intramembrane glutamic endopeptidase -
  H1W80_RS09725 (STHERMO_1899) - 1628554..1628829 (-) 276 WP_232086519.1 CAAX protease -
  H1W80_RS08415 (STHERMO_1900) - 1628841..1629038 (-) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -
  H1W80_RS08420 (STHERMO_1901) - 1629287..1630480 (-) 1194 WP_180473352.1 acetate kinase -
  H1W80_RS08425 (STHERMO_1902) comGH 1630536..1631492 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  H1W80_RS08430 (STHERMO_1903) comGG 1631537..1631854 (-) 318 WP_002952035.1 competence type IV pilus minor pilin ComGG Machinery gene
  H1W80_RS08435 (STHERMO_1904) comGF 1631832..1632269 (-) 438 WP_082309153.1 competence type IV pilus minor pilin ComGF Machinery gene
  H1W80_RS08440 (STHERMO_1905) comGE 1632253..1632546 (-) 294 WP_180473353.1 competence type IV pilus minor pilin ComGE Machinery gene
  H1W80_RS08445 (STHERMO_1906) comGD 1632518..1632946 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  H1W80_RS08450 (STHERMO_1907) comGC 1632906..1633232 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  H1W80_RS08455 (STHERMO_1908) comGB 1633229..1634329 (-) 1101 WP_180473354.1 competence type IV pilus assembly protein ComGB Machinery gene
  H1W80_RS08460 (STHERMO_1909) comGA/cglA/cilD 1634211..1635152 (-) 942 WP_022096896.1 competence type IV pilus ATPase ComGA Machinery gene
  H1W80_RS08465 (STHERMO_1910) - 1635233..1635595 (-) 363 WP_014608746.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10884.85 Da        Isoelectric Point: 10.4561

>NTDB_id=1011602 H1W80_RS08440 WP_180473353.1 1632253..1632546(-) (comGE) [Streptococcus thermophilus isolate STH_CIRM_1125]
MVNIKRRSLRGYILIESLVAMAILVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTKQDQLTLNGIAVTVKRSQQ
GITVYELGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=1011602 H1W80_RS08440 WP_180473353.1 1632253..1632546(-) (comGE) [Streptococcus thermophilus isolate STH_CIRM_1125]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGTCTGGTAGCTATGGCTATTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCAGCAA
GGTATCACGGTTTATGAATTGGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

43.299

100

0.433
  comGE Streptococcus mutans UA159

43.299

100

0.433
  comGE Lactococcus lactis subsp. cremoris KW2

36.082

100

0.361