Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   H1W80_RS07620 Genome accession   NZ_LR822040
Coordinates   1467637..1468368 (+) Length   243 a.a.
NCBI ID   WP_002948869.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1125     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1462637..1473368
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W80_RS07605 - 1463591..1465161 (+) 1571 WP_087009847.1 IS3-like element ISSth1b family transposase -
  H1W80_RS07610 (STHERMO_1700) - 1465307..1465561 (-) 255 WP_087010144.1 Blp family class II bacteriocin -
  H1W80_RS09940 (STHERMO_1701) - 1465812..1466213 (-) 402 WP_011226490.1 hypothetical protein -
  H1W80_RS07615 (STHERMO_1706) - 1467181..1467387 (-) 207 WP_084829836.1 bacteriocin class II family protein -
  H1W80_RS07620 (STHERMO_1707) comE/blpR 1467637..1468368 (+) 732 WP_002948869.1 LytR/AlgR family response regulator transcription factor Regulator
  H1W80_RS09670 comD/blpH 1468905..1469708 (+) 804 WP_224103634.1 ATP-binding protein Regulator
  H1W80_RS07630 (STHERMO_1709) - 1469726..1469887 (-) 162 WP_011226496.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  H1W80_RS07635 (STHERMO_1710) - 1469902..1471268 (-) 1367 Protein_1449 bacteriocin secretion accessory protein -

Sequence

Protein


Download         Length: 243 a.a.        Molecular weight: 27803.11 Da        Isoelectric Point: 6.9136

>NTDB_id=1011586 H1W80_RS07620 WP_002948869.1 1467637..1468368(+) (comE/blpR) [Streptococcus thermophilus isolate STH_CIRM_1125]
MKIYLLEDNSIQMGRLEEAVAHELKSFGKDLSCVQSFDKPDQLLSAITSNTSDQIFFLDIEIKGEDKKGLDIAKIIRQNN
PYAIIAFVTTHIEFMPQAFGVTAYKYINKTLDEASFRKEIGETIAQVFPINATTTDEFFLYKTESQLINLPMDQILYLST
SDIKHHVHLQTIHTLMDIRANLADFKKIHKKLYPCHRSYIVNTDMIISVNKTNYEATLINGQVLPVSRMKIGKIAQIVEE
RGR

Nucleotide


Download         Length: 732 bp        

>NTDB_id=1011586 H1W80_RS07620 WP_002948869.1 1467637..1468368(+) (comE/blpR) [Streptococcus thermophilus isolate STH_CIRM_1125]
TTGAAGATTTACCTATTAGAAGATAATTCTATTCAGATGGGTCGCTTGGAAGAGGCTGTGGCACATGAACTTAAATCCTT
CGGAAAAGATCTATCTTGTGTCCAGTCTTTTGACAAACCTGACCAGTTGTTATCAGCTATCACTTCTAATACAAGCGATC
AGATTTTCTTTCTTGATATTGAAATTAAAGGTGAAGATAAGAAGGGACTTGATATCGCTAAAATCATACGTCAAAATAAC
CCTTATGCTATCATTGCCTTTGTCACTACACATATAGAGTTCATGCCTCAAGCTTTTGGCGTTACAGCCTATAAATACAT
CAATAAAACCTTAGATGAAGCTAGCTTTAGAAAAGAAATAGGGGAAACCATTGCTCAAGTCTTCCCTATTAACGCAACTA
CCACGGATGAGTTTTTTCTCTACAAAACAGAGTCTCAATTAATAAACCTTCCTATGGATCAAATTCTATACCTATCCACA
TCAGATATCAAACACCATGTTCACCTCCAGACTATCCATACCCTCATGGATATCCGAGCAAATCTGGCAGACTTTAAAAA
GATACACAAAAAGCTCTACCCATGCCATCGGTCCTATATCGTCAATACAGATATGATCATCTCTGTCAACAAGACCAATT
ATGAAGCTACCTTAATTAATGGTCAAGTTCTACCAGTATCCCGTATGAAGATAGGAAAGATTGCACAGATTGTTGAGGAA
AGAGGCAGATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(17-119)

LytTr DNA-binding domain (LytTR)

(146-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

35.628

100

0.362