Detailed information NTG1011554

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: UXQ28_RS09715
• Genome accession: NZ_CP158488
• Coordinates: 1981456..1982499 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN92
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1976456..1987499

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXQ28_RS09685 (UXQ28_09685)	-	1976877..1978133 (-)	1257	WP_001795108.1	aminopeptidase	-
UXQ28_RS09690 (UXQ28_09690)	-	1978136..1978336 (-)	201	WP_000180460.1	DUF1128 family protein	-
UXQ28_RS09695 (UXQ28_09695)	-	1978483..1978947 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
UXQ28_RS09700 (UXQ28_09700)	-	1978954..1979229 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
UXQ28_RS09705 (UXQ28_09705)	-	1979507..1980724 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
UXQ28_RS09710 (UXQ28_09710)	vraR	1980837..1981466 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
UXQ28_RS09715 (UXQ28_09715)	vraS	1981456..1982499 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
UXQ28_RS09720 (UXQ28_09720)	liaF	1982496..1983197 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
UXQ28_RS09725 (UXQ28_09725)	-	1983212..1983598 (-)	387	WP_001110179.1	hypothetical protein	-
UXQ28_RS09730 (UXQ28_09730)	map	1983815..1984573 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
UXQ28_RS09735 (UXQ28_09735)	-	1985104..1986090 (+)	987	WP_000999717.1	aromatic acid exporter family protein	-
UXQ28_RS09740 (UXQ28_09740)	-	1986521..1986934 (-)	414	WP_001557448.1	hypothetical protein	-
UXQ28_RS09745 (UXQ28_09745)	-	1986963..1987073 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1011554 UXQ28_RS09715 WP_001017131.1 1981456..1982499(-) (vraS) [Staphylococcus aureus strain BSN92]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1011554 UXQ28_RS09715 WP_001017131.1 1981456..1982499(-) (vraS) [Staphylococcus aureus strain BSN92]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTATTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCATACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCTCGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTTTCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1