Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   H1W87_RS08590 Genome accession   NZ_LR822037
Coordinates   1651090..1651383 (-) Length   97 a.a.
NCBI ID   WP_011226625.1    Uniprot ID   Q5M2G2
Organism   Streptococcus thermophilus isolate STH_CIRM_1121     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1646090..1656383
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W87_RS08555 (STHERMO_1928) - 1646492..1646785 (-) 294 WP_232085688.1 hypothetical protein -
  H1W87_RS09875 (STHERMO_1929) - 1647010..1647435 (-) 426 WP_111679733.1 CPBP family intramembrane glutamic endopeptidase -
  H1W87_RS08565 (STHERMO_1931) - 1647678..1647875 (-) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -
  H1W87_RS08570 (STHERMO_1932) - 1648124..1649317 (-) 1194 WP_014608740.1 acetate kinase -
  H1W87_RS08575 (STHERMO_1933) comGH 1649373..1650329 (-) 957 WP_180478280.1 class I SAM-dependent methyltransferase Machinery gene
  H1W87_RS08580 (STHERMO_1934) comGG 1650374..1650691 (-) 318 WP_002952035.1 competence type IV pilus minor pilin ComGG Machinery gene
  H1W87_RS08585 (STHERMO_1935) comGF 1650669..1651106 (-) 438 WP_011681686.1 competence type IV pilus minor pilin ComGF Machinery gene
  H1W87_RS08590 (STHERMO_1936) comGE 1651090..1651383 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  H1W87_RS08595 (STHERMO_1937) comGD 1651355..1651783 (-) 429 WP_253269448.1 competence type IV pilus minor pilin ComGD Machinery gene
  H1W87_RS08600 (STHERMO_1938) comGC 1651743..1652069 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  H1W87_RS08605 (STHERMO_1939) comGB 1652066..1653166 (-) 1101 WP_116920398.1 competence type IV pilus assembly protein ComGB Machinery gene
  H1W87_RS08610 (STHERMO_1940) comGA 1653048..1653989 (-) 942 WP_180478282.1 competence type IV pilus ATPase ComGA Machinery gene
  H1W87_RS08615 (STHERMO_1941) - 1654070..1654432 (-) 363 WP_011226630.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10844.74 Da        Isoelectric Point: 10.4561

>NTDB_id=1011399 H1W87_RS08590 WP_011226625.1 1651090..1651383(-) (comGE) [Streptococcus thermophilus isolate STH_CIRM_1121]
MVNIKRRSLRGYILIESLVAMAVLVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTKQDQLTLNGIAVTVKRSQQ
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=1011399 H1W87_RS08590 WP_011226625.1 1651090..1651383(-) (comGE) [Streptococcus thermophilus isolate STH_CIRM_1121]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGTCTGGTAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCAGCAA
GGTATCACGGTTTATGAATCGGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

43.299

100

0.433
  comGE Streptococcus mutans UA159

43.299

100

0.433
  comGE Lactococcus lactis subsp. cremoris KW2

36.082

100

0.361