Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   H1X13_RS08075 Genome accession   NZ_LR822034
Coordinates   1563720..1564451 (+) Length   243 a.a.
NCBI ID   WP_180481100.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1049     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1558720..1569451
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1X13_RS08060 - 1559673..1561243 (+) 1571 WP_180481099.1 IS3-like element ISSth1b family transposase -
  H1X13_RS08065 (STHERMO_1798) - 1561389..1561643 (-) 255 WP_054571825.1 Blp family class II bacteriocin -
  H1X13_RS10450 (STHERMO_1799) - 1561894..1562295 (-) 402 WP_011226490.1 hypothetical protein -
  H1X13_RS08070 (STHERMO_1802) - 1563263..1563469 (-) 207 WP_084829836.1 bacteriocin class II family protein -
  H1X13_RS08075 (STHERMO_1803) comE/blpR 1563720..1564451 (+) 732 WP_180481100.1 LytR/AlgR family response regulator transcription factor Regulator
  H1X13_RS10150 comD/blpH 1564988..1565791 (+) 804 WP_224103634.1 ATP-binding protein Regulator
  H1X13_RS08085 (STHERMO_1805) - 1565809..1565970 (-) 162 WP_011226496.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  H1X13_RS08090 (STHERMO_1806) comB 1565985..1567352 (-) 1368 WP_084829837.1 bacteriocin secretion accessory protein Regulator

Sequence

Protein


Download         Length: 243 a.a.        Molecular weight: 27745.07 Da        Isoelectric Point: 7.1718

>NTDB_id=1011072 H1X13_RS08075 WP_180481100.1 1563720..1564451(+) (comE/blpR) [Streptococcus thermophilus isolate STH_CIRM_1049]
MKIYLLEDNSIQMGRLEEAVAHELKSFGKDLSCVQSFDKPDQLLSAITSNTSDQIFFLDIEIKGEDKKGLDIAKIIRQNN
PYAIIAFVTTHIEFMPQAFGVTAYKYINKTLDEASFRKEIGETIAQVFPINATTTDEFFLYKTESQLINLPMDQILYLST
SDIKHHVHLQTIHTLMDIRANLADFKKIHKKLYPCHRSYIVNTGMIISVNKTNYEATLINGQVLPVSRMKIGKIAQIVEE
RGR

Nucleotide


Download         Length: 732 bp        

>NTDB_id=1011072 H1X13_RS08075 WP_180481100.1 1563720..1564451(+) (comE/blpR) [Streptococcus thermophilus isolate STH_CIRM_1049]
TTGAAGATTTACCTATTAGAAGATAATTCTATTCAGATGGGTCGCTTGGAAGAGGCTGTGGCACATGAACTTAAATCCTT
CGGAAAAGATCTATCTTGTGTCCAGTCTTTTGACAAACCTGACCAGTTGTTATCAGCTATCACTTCTAATACAAGCGATC
AGATTTTCTTTCTTGATATTGAAATTAAAGGTGAAGATAAGAAGGGACTTGATATCGCTAAAATCATACGTCAAAATAAC
CCTTATGCTATCATTGCCTTTGTCACTACACATATAGAGTTCATGCCTCAAGCTTTTGGCGTTACAGCCTATAAATACAT
CAATAAAACCTTAGATGAAGCTAGCTTTAGAAAAGAAATAGGGGAAACCATTGCTCAAGTCTTCCCTATTAACGCAACTA
CCACGGATGAGTTTTTTCTCTACAAAACAGAGTCTCAATTAATAAACCTTCCTATGGATCAAATTCTATACCTATCCACA
TCAGATATCAAACACCATGTTCACCTCCAGACTATCCATACCCTCATGGATATCCGAGCAAATCTGGCAGACTTTAAAAA
GATACACAAAAAGCTCTACCCATGCCATCGGTCCTATATCGTCAATACAGGTATGATCATCTCTGTCAACAAGACCAATT
ATGAAGCTACCTTAATTAATGGTCAAGTTCTACCAGTATCCCGTATGAAGATAGGAAAGATTGCACAGATTGTTGAGGAA
AGAGGCAGATGA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(146-237)

Response regulator receiver domain (Response_reg)

(17-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

35.628

100

0.362