Detailed information NTG1011036

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: LLUC023_RS11830
• Genome accession: NZ_CP158368
• Coordinates: 2299459..2300490 (-)
• Length: 343 a.a.
• NCBI ID: WP_011677213.1
• Uniprot ID: A0A166ZHD8
• Organism: Lactococcus cremoris strain UC023
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 2294459..2305490

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LLUC023_RS11795 (LLUC023_11805)	-	2295155..2295652 (-)	498	WP_011677211.1	nitroreductase family protein	-
LLUC023_RS11800 (LLUC023_11810)	-	2295675..2295854 (-)	180	WP_050574404.1	hypothetical protein	-
LLUC023_RS11805 (LLUC023_11815)	-	2295851..2296075 (-)	225	WP_021211256.1	hypothetical protein	-
LLUC023_RS11810 (LLUC023_11820)	-	2296142..2297032 (+)	891	Protein_2298	IS982 family transposase	-
LLUC023_RS11815 (LLUC023_11825)	-	2297246..2298357 (+)	1112	WP_205287927.1	IS3-like element IS981 family transposase	-
LLUC023_RS11820 (LLUC023_11830)	-	2298390..2298959 (-)	570	WP_242515033.1	radical SAM protein	-
LLUC023_RS11825 (LLUC023_11835)	-	2299027..2299140 (-)	114	WP_011836076.1	KxxxW-cyclized peptide pheromone	-
LLUC023_RS11830 (LLUC023_11840)	sepM	2299459..2300490 (-)	1032	WP_011677213.1	SepM family pheromone-processing serine protease	Regulator
LLUC023_RS11835 (LLUC023_11845)	coaD	2300474..2300974 (-)	501	WP_011677214.1	pantetheine-phosphate adenylyltransferase	-
LLUC023_RS11840 (LLUC023_11850)	rsmD	2301022..2301561 (-)	540	WP_031286167.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
LLUC023_RS11845 (LLUC023_11855)	-	2301732..2302952 (-)	1221	WP_011677216.1	MFS transporter	-
LLUC023_RS11850 (LLUC023_11860)	lmrP	2303036..2304262 (-)	1227	Protein_2306	multidrug efflux MFS transporter LmrP	-
LLUC023_RS11855 (LLUC023_11865)	-	2304450..2304944 (+)	495	WP_021211251.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 343 a.a.
• Molecular weight: 37398.03 Da
• Isoelectric Point: 9.8499

>NTDB_id=1011036 LLUC023_RS11830 WP_011677213.1 2299459..2300490(-) (sepM) [Lactococcus cremoris strain UC023]
MKKKNKKISPKLKWGISIGLIIVALLVLVYPTNYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYS
HFNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAVYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELSDTITA
VNGEEFKSSADMIAYVSKQKVGDSVTIEYTRIDGSKHKSTGKYIKIANGKTGIGIGLVDHTEVVTDPKVTVNAGSIGGPS
AGIMFTLEIYSQLTGKDLRGGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAK
KLKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1032 bp

>NTDB_id=1011036 LLUC023_RS11830 WP_011677213.1 2299459..2300490(-) (sepM) [Lactococcus cremoris strain UC023]
ATGAAGAAAAAAAATAAAAAAATCAGTCCCAAATTAAAATGGGGCATCTCTATTGGTCTGATTATTGTCGCTCTCCTTGT
TTTAGTGTATCCAACAAATTACTATGTGGAAATGCCTGGAACAACCGAGCCATTAGGAAAAATGGTCAAAGTCGAAGGAA
AAAAAGATGAGCACAAAGGTGACTTTTTCCTTACTACCGTTCAAATTGCGCGCGCTAATCTTGCCACAATGATTTACAGT
CATTTTAATAGTTTTACAAGCATTTACAGTGAACAAGAAATGACCGGTGGCCTTAATGATGCGCAGTTCAATCGTGTCAA
CCAGTTTTACATGGAAACGGCACAAAATACAGCCGTTTATCAGGCCTTCAAGTTGGCAAATAAACCCTATGAACTGAAAT
ATGAAGGGGTTTATGTCCTTGATATCGCTAAAAATTCGACTTTTAAAAATAAATTGGAACTTTCGGACACGATTACAGCA
GTCAATGGGGAAGAATTTAAATCAAGTGCAGATATGATTGCTTACGTTTCGAAGCAAAAAGTCGGCGATTCAGTTACCAT
TGAATATACACGGATTGATGGAAGTAAACACAAGTCTACTGGAAAATATATCAAAATCGCTAATGGAAAAACTGGAATCG
GAATTGGACTAGTTGACCATACTGAAGTAGTCACAGACCCAAAAGTTACAGTCAATGCAGGTTCAATCGGTGGACCATCT
GCCGGAATAATGTTTACACTAGAGATTTACAGTCAGTTGACAGGTAAAGATTTACGTGGTGGTCGCGAAATAGCAGGAAC
TGGAACGATTGAACATGATGGAAGCATTGGCCAAATCGGTGGGGTTGATAAAAAAGTAGCTACTGCTAGCAAAGAAGGCG
CAAAAGTTTTCTTAGTTCCTGACTCAGGCACCAAAAAAGAAAGCAGCAATAACTATCTTGGAGCCAAAGCAGCCGCTAAA
AAATTAAAAACGAAGATGAAAATTGTTCCCGTCAAGACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (229-339)

• PDZ domain (PDZ_2) (135-193)

3D structure

• AlphaFold DB: A0A166ZHD8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.49