Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   H1W90_RS08900 Genome accession   NZ_LR822033
Coordinates   1726958..1727251 (-) Length   97 a.a.
NCBI ID   WP_011226625.1    Uniprot ID   Q5M2G2
Organism   Streptococcus thermophilus isolate STH_CIRM_1048     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1721958..1732251
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W90_RS08865 (STHERMO_1987) - 1722360..1722803 (-) 444 WP_180481125.1 CAAX protease -
  H1W90_RS10195 (STHERMO_1988) - 1722877..1723215 (-) 339 WP_224103672.1 CPBP family intramembrane glutamic endopeptidase -
  H1W90_RS10200 (STHERMO_1989) - 1723259..1723534 (-) 276 WP_011681681.1 hypothetical protein -
  H1W90_RS08875 (STHERMO_1990) - 1723546..1723743 (-) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -
  H1W90_RS08880 (STHERMO_1991) - 1723992..1725185 (-) 1194 WP_096811682.1 acetate kinase -
  H1W90_RS08885 (STHERMO_1992) comGH 1725241..1726197 (-) 957 WP_180481126.1 class I SAM-dependent methyltransferase Machinery gene
  H1W90_RS08890 (STHERMO_1993) comGG 1726242..1726559 (-) 318 WP_002952035.1 competence type IV pilus minor pilin ComGG Machinery gene
  H1W90_RS08895 (STHERMO_1994) comGF 1726537..1726974 (-) 438 WP_011681686.1 competence type IV pilus minor pilin ComGF Machinery gene
  H1W90_RS08900 (STHERMO_1995) comGE 1726958..1727251 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  H1W90_RS08905 (STHERMO_1996) comGD 1727223..1727651 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  H1W90_RS08910 (STHERMO_1997) comGC 1727611..1727937 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  H1W90_RS08915 (STHERMO_1998) comGB 1727934..1729034 (-) 1101 WP_116920398.1 competence type IV pilus assembly protein ComGB Machinery gene
  H1W90_RS08920 (STHERMO_1999) comGA/cglA/cilD 1728916..1729857 (-) 942 WP_022096896.1 competence type IV pilus ATPase ComGA Machinery gene
  H1W90_RS08925 (STHERMO_2000) - 1729938..1730300 (-) 363 WP_180481127.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10844.74 Da        Isoelectric Point: 10.4561

>NTDB_id=1010979 H1W90_RS08900 WP_011226625.1 1726958..1727251(-) (comGE) [Streptococcus thermophilus isolate STH_CIRM_1048]
MVNIKRRSLRGYILIESLVAMAVLVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTKQDQLTLNGIAVTVKRSQQ
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=1010979 H1W90_RS08900 WP_011226625.1 1726958..1727251(-) (comGE) [Streptococcus thermophilus isolate STH_CIRM_1048]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGTCTGGTAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCAGCAA
GGTATCACGGTTTATGAATCGGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

43.299

100

0.433
  comGE Streptococcus mutans UA159

43.299

100

0.433
  comGE Lactococcus lactis subsp. cremoris KW2

36.082

100

0.361