Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE   Type   Machinery gene
Locus tag   H1W91_RS08895 Genome accession   NZ_LR822032
Coordinates   1708327..1708620 (-) Length   97 a.a.
NCBI ID   WP_011226625.1    Uniprot ID   Q5M2G2
Organism   Streptococcus thermophilus isolate STH_CIRM_1050     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1703327..1713620
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W91_RS08860 (STHERMO_1962) - 1703731..1704173 (-) 443 Protein_1691 CAAX protease -
  H1W91_RS10205 (STHERMO_1963) - 1704247..1704672 (-) 426 WP_111679733.1 CPBP family intramembrane glutamic endopeptidase -
  H1W91_RS08870 (STHERMO_1965) - 1704915..1705112 (-) 198 WP_002885716.1 helix-turn-helix transcriptional regulator -
  H1W91_RS08875 (STHERMO_1966) - 1705361..1706554 (-) 1194 WP_014608740.1 acetate kinase -
  H1W91_RS08880 (STHERMO_1967) comGH 1706610..1707566 (-) 957 WP_180477178.1 class I SAM-dependent methyltransferase Machinery gene
  H1W91_RS08885 (STHERMO_1968) comGG 1707611..1707928 (-) 318 WP_180477179.1 competence type IV pilus minor pilin ComGG Machinery gene
  H1W91_RS08890 (STHERMO_1969) comGF 1707906..1708343 (-) 438 WP_082309153.1 competence type IV pilus minor pilin ComGF Machinery gene
  H1W91_RS08895 (STHERMO_1970) comGE 1708327..1708620 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  H1W91_RS08900 (STHERMO_1971) comGD 1708592..1709020 (-) 429 WP_253269448.1 competence type IV pilus minor pilin ComGD Machinery gene
  H1W91_RS08905 (STHERMO_1972) comGC 1708980..1709306 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  H1W91_RS08910 (STHERMO_1973) comGB 1709303..1710403 (-) 1101 WP_120764773.1 competence type IV pilus assembly protein ComGB Machinery gene
  H1W91_RS08915 (STHERMO_1974) comGA/cglA/cilD 1710285..1711226 (-) 942 WP_022096896.1 competence type IV pilus ATPase ComGA Machinery gene
  H1W91_RS08920 (STHERMO_1975) - 1711307..1711669 (-) 363 WP_014608746.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 97 a.a.        Molecular weight: 10844.74 Da        Isoelectric Point: 10.4561

>NTDB_id=1010868 H1W91_RS08895 WP_011226625.1 1708327..1708620(-) (comGE) [Streptococcus thermophilus isolate STH_CIRM_1050]
MVNIKRRSLRGYILIESLVAMAVLVLVSSLILEQINTNRRLMADNLHQQEVLSVATMAVQTKQDQLTLNGIAVTVKRSQQ
GITVYESGKEIIHVSKQ

Nucleotide


Download         Length: 294 bp        

>NTDB_id=1010868 H1W91_RS08895 WP_011226625.1 1708327..1708620(-) (comGE) [Streptococcus thermophilus isolate STH_CIRM_1050]
GTGGTAAATATAAAAAGACGATCTCTTAGAGGTTATATTCTTATTGAAAGTCTGGTAGCTATGGCTGTTTTAGTACTTGT
CAGCAGTCTGATATTGGAACAAATTAATACCAACCGCAGACTAATGGCTGATAATCTCCATCAACAAGAGGTCTTGAGTG
TGGCAACAATGGCAGTTCAGACCAAGCAAGACCAGTTAACGCTGAATGGCATAGCGGTGACAGTTAAACGTAGCCAGCAA
GGTATCACGGTTTATGAATCGGGAAAGGAGATTATTCATGTATCTAAGCAGTAA

Domains

Predicted by InterProScan.

Type II secretory pathway pseudopilin (ComGE)

(13-94)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE Streptococcus mutans UA140

43.299

100

0.433
  comGE Streptococcus mutans UA159

43.299

100

0.433
  comGE Lactococcus lactis subsp. cremoris KW2

36.082

100

0.361

Multiple sequence alignment