Detailed information NTG1010838

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: H1W91_RS06930
• Genome accession: NZ_LR822032
• Coordinates: 1328113..1329198 (-)
• Length: 361 a.a.
• NCBI ID: WP_011226304.1
• Uniprot ID: Q5M3H6
• Organism: Streptococcus thermophilus isolate STH_CIRM_1050
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1323113..1334198

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W91_RS06900 (STHERMO_1512)	-	1323475..1324293 (-)	819	WP_011681411.1	Cof-type HAD-IIB family hydrolase	-
H1W91_RS06905 (STHERMO_1513)	-	1324286..1325080 (-)	795	WP_180477091.1	HAD hydrolase family protein	-
H1W91_RS06910 (STHERMO_1514)	-	1325264..1325641 (+)	378	WP_011226300.1	GntR family transcriptional regulator	-
H1W91_RS06915 (STHERMO_1515)	-	1325646..1326344 (+)	699	WP_022096876.1	ABC transporter ATP-binding protein	-
H1W91_RS06920 (STHERMO_1516)	-	1326356..1327141 (+)	786	WP_180477092.1	ABC transporter permease	-
H1W91_RS06925 (STHERMO_1517)	-	1327191..1328120 (-)	930	WP_002951426.1	ATP-binding cassette domain-containing protein	-
H1W91_RS06930 (STHERMO_1518)	amiE	1328113..1329198 (-)	1086	WP_011226304.1	ABC transporter ATP-binding protein	Regulator
H1W91_RS06935 (STHERMO_1519)	amiD	1329208..1330134 (-)	927	WP_002946409.1	oligopeptide ABC transporter permease OppC	Regulator
H1W91_RS06940 (STHERMO_1520)	amiC	1330134..1331627 (-)	1494	WP_011227407.1	ABC transporter permease	Regulator
H1W91_RS06945 (STHERMO_1521)	amiA	1331689..1333656 (-)	1968	WP_180477093.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 361 a.a.
• Molecular weight: 39864.62 Da
• Isoelectric Point: 4.7435

>NTDB_id=1010838 H1W91_RS06930 WP_011226304.1 1328113..1329198(-) (amiE) [Streptococcus thermophilus isolate STH_CIRM_1050]
MTENKNVILSARDIVVEFDVRDRVLTAIRGVSLDLVEGEVLALVGESGSGKSVLTKTFTGMLEENGRVASGSIDYRGKDL
TKFKSHQDWAAIRGAKIATIFQDPMTSLNPIKTIGSQIIEVIVKHQGKTAKEAKKMAIDYMDKVGIPDAEKRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLKEEYGFSVIFITHDLGVVASIADKVAVMYAGEIIE
YATVEEIFYEPCHPYTWSLLSSLPQLADDNGKLFSIPGTPPSLYTPVVGDAFALRSDYALQIDFEEKAPQFQVSDTHWAK
TWLLHEDAPKVDKPAVIQNLHEKILANMGFAHLGDEEEGNA

Nucleotide

• Length: 1086 bp

>NTDB_id=1010838 H1W91_RS06930 WP_011226304.1 1328113..1329198(-) (amiE) [Streptococcus thermophilus isolate STH_CIRM_1050]
ATGACAGAAAATAAAAATGTAATATTATCGGCTCGCGATATCGTCGTGGAATTTGACGTTCGTGACCGTGTTTTGACAGC
TATTCGAGGGGTTTCCCTTGATTTAGTTGAAGGTGAAGTTTTAGCCTTGGTTGGTGAATCTGGTTCAGGAAAATCAGTCT
TGACTAAAACTTTTACAGGGATGCTGGAAGAAAATGGTCGTGTAGCTAGCGGATCTATCGACTACCGTGGCAAAGACTTG
ACTAAATTTAAGAGTCACCAAGATTGGGCAGCTATCCGTGGAGCTAAGATTGCAACTATTTTCCAAGATCCAATGACCAG
TCTTAACCCAATTAAGACTATCGGAAGTCAAATTATTGAAGTTATTGTTAAGCACCAAGGGAAAACAGCCAAGGAAGCTA
AAAAAATGGCAATTGATTACATGGACAAGGTTGGTATTCCAGATGCTGAAAAACGTTTCAATGAATATCCTTTCCAATAC
TCTGGTGGGATGCGTCAACGTATCGTTATTGCCATTGCCTTGGCTTGTCGTCCTGATGTCCTTATCTGTGACGAACCAAC
AACTGCCCTTGATGTGACCATTCAAGCTCAAATCATTGACCTCTTGAAATCACTCAAAGAGGAGTATGGTTTCTCGGTCA
TTTTCATTACCCATGACCTTGGCGTCGTAGCAAGTATCGCGGACAAGGTTGCTGTCATGTATGCTGGCGAAATCATTGAA
TACGCAACTGTTGAGGAAATTTTCTATGAGCCTTGTCATCCATACACGTGGAGCTTGCTTTCAAGTCTGCCACAATTGGC
TGATGATAATGGAAAACTCTTCTCAATTCCAGGGACGCCACCATCACTTTATACACCAGTTGTTGGGGATGCCTTTGCCT
TGCGTTCAGATTATGCTTTGCAGATTGATTTTGAGGAAAAAGCACCACAATTCCAAGTTTCAGATACTCACTGGGCTAAG
ACCTGGCTCTTACATGAGGATGCGCCAAAAGTTGATAAACCTGCGGTTATCCAAAATCTACATGAAAAAATCCTAGCCAA
TATGGGATTTGCACATTTAGGAGATGAGGAGGAAGGCAATGCCTGA

Domains

Predicted by InterProScan.

• ABC transporter (ABC_tran) (29-187)

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-300)

3D structure

• AlphaFold DB: Q5M3H6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus thermophilus LMG 18311	100	100	1
amiE	Streptococcus thermophilus LMD-9	100	100	1
amiE	Streptococcus salivarius strain HSISS4	96.953	100	0.97
oppD	Streptococcus mutans UA159	54.441	96.676	0.526