Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   H1W74_RS09885 Genome accession   NZ_LR822031
Coordinates   1478320..1479123 (+) Length   267 a.a.
NCBI ID   WP_224103634.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1047     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1473320..1484123
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W74_RS07605 (STHERMO_1724) - 1473724..1474650 (-) 927 WP_022096485.1 thioredoxin family protein -
  H1W74_RS07610 - 1474844..1476414 (+) 1571 WP_087009847.1 IS3-like element ISSth1b family transposase -
  H1W74_RS07615 (STHERMO_1727) - 1476560..1476802 (-) 243 WP_002948868.1 Blp family class II bacteriocin -
  H1W74_RS07620 (STHERMO_1728) comE/blpR 1477052..1477783 (+) 732 WP_002948869.1 LytR/AlgR family response regulator transcription factor Regulator
  H1W74_RS09885 comD/blpH 1478320..1479123 (+) 804 WP_224103634.1 ATP-binding protein Regulator
  H1W74_RS07630 (STHERMO_1730) - 1479141..1479302 (-) 162 WP_011226496.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  H1W74_RS07635 - 1479317..1480685 (-) 1369 Protein_1468 bacteriocin secretion accessory protein -
  H1W74_RS07640 (STHERMO_1733) - 1480701..1482791 (-) 2091 Protein_1469 peptide cleavage/export ABC transporter -

Sequence

Protein


Download         Length: 267 a.a.        Molecular weight: 30835.17 Da        Isoelectric Point: 4.8309

>NTDB_id=1010773 H1W74_RS09885 WP_224103634.1 1478320..1479123(+) (comD/blpH) [Streptococcus thermophilus isolate STH_CIRM_1047]
MYLENTTHSSTLELRKLCVVISLVLFFIMIVFLERNIREMIQGQLDFQKNLQLENLYTYNKHIECLYNSVRSFRHDYSNL
LVTLRLGIDKDDMDIVKEVYDSVLQESDKRLNTRNFDLARLVNIQDNTLKSLLSAKVLQAEEEGIEAQISIPEPIHLIGM
EILDFIIVTSIFLDNAIEGAIQTQNHKITISFWEDHRSQLLSISNTISEEQTETKTIFERGVSNKGRERGIGLANVTEIL
DNYINVNLETQSNNFSFTQQLTITKKA

Nucleotide


Download         Length: 804 bp        

>NTDB_id=1010773 H1W74_RS09885 WP_224103634.1 1478320..1479123(+) (comD/blpH) [Streptococcus thermophilus isolate STH_CIRM_1047]
ATGTATCTTGAAAACACTACTCACTCTTCAACTTTGGAGCTTCGAAAACTCTGTGTTGTTATTTCACTTGTCCTCTTCTT
CATTATGATTGTCTTTTTAGAAAGAAACATTCGTGAAATGATTCAAGGACAATTGGACTTCCAGAAAAATCTCCAGCTAG
AGAATCTCTACACCTACAATAAACATATTGAATGTCTCTACAATTCTGTTCGTAGTTTTAGACACGATTATAGTAATCTC
TTAGTCACATTACGATTGGGGATAGATAAAGACGATATGGATATTGTCAAAGAAGTCTATGATAGTGTGCTTCAAGAATC
CGATAAACGATTAAATACAAGAAACTTTGACTTAGCTAGACTCGTTAATATTCAGGATAATACTTTGAAAAGCCTTCTGT
CCGCAAAAGTTTTACAAGCAGAAGAAGAAGGTATTGAAGCTCAGATTAGCATCCCAGAACCCATCCACTTGATTGGGATG
GAGATTCTGGACTTCATTATCGTCACTTCTATTTTTTTAGATAACGCTATTGAAGGTGCCATTCAAACTCAAAACCATAA
AATTACTATTAGCTTTTGGGAAGATCATCGTTCACAGCTATTATCTATTAGCAATACCATAAGTGAAGAACAAACAGAAA
CTAAAACCATATTTGAAAGAGGTGTCTCCAACAAGGGACGAGAGCGAGGCATTGGCCTTGCTAATGTCACAGAAATCTTA
GATAACTATATCAATGTAAACTTAGAAACACAGAGTAACAATTTCTCATTCACACAACAATTAACAATAACTAAAAAGGC
CTAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(160-263)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

38.189

95.131

0.363

Multiple sequence alignment