Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   H1W74_RS06135 Genome accession   NZ_LR822031
Coordinates   1182924..1183604 (-) Length   226 a.a.
NCBI ID   WP_002945967.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_1047     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1177924..1188604
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W74_RS06105 (STHERMO_1384) - 1178132..1178581 (-) 450 WP_011226219.1 cytidine deaminase family protein -
  H1W74_RS06110 (STHERMO_1385) - 1178592..1178771 (-) 180 Protein_1163 ABC transporter permease -
  H1W74_RS06115 (STHERMO_1386) - 1178773..1178970 (-) 198 Protein_1164 YkgJ family cysteine cluster protein -
  H1W74_RS06120 (STHERMO_1387) - 1179055..1181055 (-) 2001 WP_022097081.1 ABC transporter permease -
  H1W74_RS06125 (STHERMO_1388) - 1181057..1181815 (-) 759 WP_022097082.1 ABC transporter ATP-binding protein -
  H1W74_RS06130 (STHERMO_1389) - 1181960..1182934 (-) 975 WP_022097083.1 sensor histidine kinase -
  H1W74_RS06135 (STHERMO_1390) braR 1182924..1183604 (-) 681 WP_002945967.1 response regulator transcription factor Regulator
  H1W74_RS06140 (STHERMO_1391) - 1184055..1184635 (+) 581 Protein_1169 xanthine phosphoribosyltransferase -
  H1W74_RS06145 - 1184635..1185907 (+) 1273 Protein_1170 nucleobase:cation symporter-2 family protein -
  H1W74_RS06150 (STHERMO_1395) - 1186035..1187384 (+) 1350 WP_014621757.1 MATE family efflux transporter -

Sequence

Protein


Download         Length: 226 a.a.        Molecular weight: 26150.55 Da        Isoelectric Point: 5.0092

>NTDB_id=1010727 H1W74_RS06135 WP_002945967.1 1182924..1183604(-) (braR) [Streptococcus thermophilus isolate STH_CIRM_1047]
MHKILLVEDDEVIRQQVKKMLEQWGYEVVLVEDFMEVLSIFVKVEPHLVLMDIGLPLFNGYHWCQEIRKVSKVPIMFLSS
RDQAMDIVMAINMGGDDFVTKPFDQNVLLAKIQGLLRRSYEFGKDQSLLEYMGVILNLKAMDLVYQGEVVSLTKNEFQIL
QVLFERSGNIVSREDLMKELWNSDFFIDDNTLSVNVARLRKKLEVVGLKDFIETKKGVGYGLRHDG

Nucleotide


Download         Length: 681 bp        

>NTDB_id=1010727 H1W74_RS06135 WP_002945967.1 1182924..1183604(-) (braR) [Streptococcus thermophilus isolate STH_CIRM_1047]
ATGCATAAGATTTTATTAGTTGAGGACGACGAGGTTATCCGTCAACAAGTCAAAAAAATGCTAGAACAGTGGGGTTACGA
AGTTGTTCTTGTTGAAGATTTCATGGAAGTATTATCTATTTTTGTAAAAGTAGAGCCCCACTTGGTTCTTATGGACATTG
GTTTACCTCTATTTAATGGTTATCATTGGTGTCAGGAAATTCGTAAGGTCTCCAAGGTGCCTATTATGTTCTTGTCTTCC
AGAGATCAGGCCATGGATATCGTTATGGCAATCAATATGGGTGGGGACGACTTTGTGACTAAACCCTTTGACCAAAATGT
TCTCTTGGCAAAAATTCAAGGGCTTTTGCGCCGATCTTATGAGTTTGGAAAGGATCAGAGTCTTTTGGAATATATGGGTG
TGATTCTGAACCTTAAGGCCATGGATCTGGTTTATCAGGGAGAAGTCGTTTCTTTGACTAAGAATGAATTTCAGATTTTA
CAAGTTCTCTTCGAGCGTTCTGGTAATATCGTTAGTCGTGAAGACCTCATGAAGGAGCTTTGGAATAGTGACTTCTTTAT
TGATGATAACACTCTCTCTGTAAATGTGGCACGTTTACGTAAGAAGTTAGAGGTAGTTGGTTTGAAGGACTTTATTGAAA
CCAAGAAAGGTGTCGGTTACGGGTTGCGTCATGATGGATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

52.294

96.46

0.504