Detailed information    

insolico Bioinformatically predicted

Overview

Name   mutX   Type   Machinery gene
Locus tag   H1W74_RS05235 Genome accession   NZ_LR822031
Coordinates   1003176..1003658 (-) Length   160 a.a.
NCBI ID   WP_011226072.1    Uniprot ID   Q5M461
Organism   Streptococcus thermophilus isolate STH_CIRM_1047     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 998176..1008658
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1W74_RS05215 (STHERMO_1193) pepT 998656..999879 (-) 1224 WP_022096765.1 peptidase T -
  H1W74_RS05220 (STHERMO_1194) lepB 1000088..1000645 (-) 558 WP_002945984.1 signal peptidase I -
  H1W74_RS05225 (STHERMO_1195) - 1000768..1001997 (-) 1230 WP_011681192.1 tetratricopeptide repeat protein -
  H1W74_RS05230 (STHERMO_1196) - 1001987..1003165 (-) 1179 WP_011227264.1 AI-2E family transporter -
  H1W74_RS05235 (STHERMO_1197) mutX 1003176..1003658 (-) 483 WP_011226072.1 NUDIX hydrolase Machinery gene
  H1W74_RS05240 (STHERMO_1198) ftsX 1003814..1004743 (-) 930 WP_022096764.1 permease-like cell division protein FtsX -
  H1W74_RS05245 (STHERMO_1199) ftsE 1004736..1005428 (-) 693 WP_022096763.1 cell division ATP-binding protein FtsE -
  H1W74_RS05255 (STHERMO_1201) queG 1006667..1007785 (-) 1119 WP_180473077.1 tRNA epoxyqueuosine(34) reductase QueG -

Sequence

Protein


Download         Length: 160 a.a.        Molecular weight: 18869.36 Da        Isoelectric Point: 4.7200

>NTDB_id=1010717 H1W74_RS05235 WP_011226072.1 1003176..1003658(-) (mutX) [Streptococcus thermophilus isolate STH_CIRM_1047]
MTKLATICYIDNGKELLLLHRNKKPNDVHEGKWISVGGKLEAGETPDECARREIFEETHLTVKKMDFKGMITFPEFTPGH
DWYTYVFKVTDFEGKLISDEESREGTLEWVPYDQVLTKQTWEGDYEIFKWILEDKPFFSAKFSYDCNQNLIDKTVTFYDK

Nucleotide


Download         Length: 483 bp        

>NTDB_id=1010717 H1W74_RS05235 WP_011226072.1 1003176..1003658(-) (mutX) [Streptococcus thermophilus isolate STH_CIRM_1047]
ATGACAAAGTTAGCTACCATTTGTTATATTGACAATGGGAAGGAGCTTTTGCTCCTACATCGTAATAAAAAGCCTAATGA
TGTTCATGAAGGAAAGTGGATTTCTGTCGGGGGAAAACTAGAAGCGGGAGAAACGCCTGACGAATGTGCTCGTCGTGAAA
TTTTCGAGGAAACTCATTTGACAGTGAAAAAGATGGACTTCAAAGGTATGATTACCTTCCCAGAATTTACTCCGGGCCAC
GATTGGTATACCTATGTCTTTAAGGTGACTGATTTTGAAGGAAAACTCATTTCTGATGAGGAATCTCGTGAAGGGACACT
TGAATGGGTACCATATGATCAGGTTTTAACTAAACAAACCTGGGAAGGTGACTATGAGATTTTTAAGTGGATTCTAGAAG
ATAAACCTTTCTTCTCTGCAAAATTTAGCTACGATTGTAACCAAAACTTGATAGATAAAACTGTAACATTTTATGATAAA
TAA

Domains

Predicted by InterProScan.

NUDIX domain (NUDIX)

(3-130)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M461

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mutX Streptococcus pneumoniae R6

71.069

99.375

0.706