Detailed information NTG1010638

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: H1W95_RS07680
• Genome accession: NZ_LR822030
• Coordinates: 1495224..1497323 (-)
• Length: 699 a.a.
• NCBI ID: WP_011681535.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_1046
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1490224..1502323

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H1W95_RS07650 (STHERMO_1722)	pptB	1490690..1491724 (-)	1035	WP_375709249.1	ABC transporter permease	Regulator
H1W95_RS07655 (STHERMO_1723)	pptA	1491724..1492455 (-)	732	WP_002951673.1	ABC transporter ATP-binding protein	Regulator
H1W95_RS07660 (STHERMO_1724)	-	1492520..1492939 (+)	420	WP_180483375.1	HIT family protein	-
H1W95_RS07665 (STHERMO_1725)	-	1492936..1493244 (+)	309	WP_116920336.1	hypothetical protein	-
H1W95_RS10310 (STHERMO_1726)	-	1493796..1493966 (-)	171	WP_011226439.1	hypothetical protein	-
H1W95_RS07675 (STHERMO_1727)	-	1494036..1494671 (-)	636	WP_064355817.1	DUF4230 domain-containing protein	-
H1W95_RS10525	-	1494690..1494815 (-)	126	WP_011681534.1	hypothetical protein	-
H1W95_RS07680 (STHERMO_1728)	clpE	1495224..1497323 (-)	2100	WP_011681535.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
H1W95_RS07685 (STHERMO_1729)	-	1498038..1499129 (-)	1092	WP_011681536.1	nucleotidyltransferase	-
H1W95_RS07690 (STHERMO_1730)	-	1499136..1499876 (-)	741	WP_277426406.1	class I SAM-dependent DNA methyltransferase	-
H1W95_RS07695 (STHERMO_1731)	rsfS	1500201..1500554 (-)	354	WP_011227491.1	ribosome silencing factor	-
H1W95_RS07700 (STHERMO_1732)	yqeK	1500578..1501168 (-)	591	WP_002951696.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
H1W95_RS07705 (STHERMO_1733)	-	1501165..1501797 (-)	633	WP_002951698.1	nicotinate-nucleotide adenylyltransferase	-
H1W95_RS07710 (STHERMO_1734)	yhbY	1501901..1502218 (-)	318	WP_002951701.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77200.11 Da
• Isoelectric Point: 4.8280

>NTDB_id=1010638 H1W95_RS07680 WP_011681535.1 1495224..1497323(-) (clpE) [Streptococcus thermophilus isolate STH_CIRM_1046]
MNNNFNNMDDLFNQLMGNMGGFRSESRRYMINGREVTPEEFAIYRQTGKLPGNQGEAVNPTQQHGPKQDGILAKLGRNLT
QEAREGKLDPVIGRNKEIQETAEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKDKEIISIDISALEAGT
QYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGEITVIGATTQDEYRNTILKNA
ALARRFNEVKVNAPSPEDTFKILQGIRDLYEKHHNVILPDEVLKAAVDFSVQYIPQRSLPDKAIDLLDMTAAHLAAQHPV
TDVNAVEREIEEEKAKQEAAVAKEDYEAALNSKIRIEKLEKEIANHAKDRKVTATVNDVAESVERMTGIPVSQMGASDIE
RLKDMGNRLQAKVIGQDKAVEAVARSIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDLFGTKDAIIRLDMSEY
SDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIA
TSNAGFGYESNSTEDADKPELMDRLKPYFRPEFLNRFDAVIEFSHLDKEDLSKIVDLMLNEVNKTLSKKGIDLAVSEAAK
AYMTEEGYDEVMGARPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK

Nucleotide

• Length: 2100 bp

>NTDB_id=1010638 H1W95_RS07680 WP_011681535.1 1495224..1497323(-) (clpE) [Streptococcus thermophilus isolate STH_CIRM_1046]
ATGAACAACAACTTTAATAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTTCCGTTCAGAAAGCCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCAATTTACCGTCAAACAGGTAAATTGCCTGGTAATC
AAGGTGAAGCAGTGAACCCAACACAACAACACGGACCTAAACAAGATGGTATTCTTGCTAAGCTTGGTCGTAACTTGACT
CAAGAAGCTCGTGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAACTGCCGAAATTTTGTCTCG
TCGTACTAAGAATAACCCAGTCCTTGTCGGTGATGCTGGGGTTGGTAAAACAGCTGTAGTTGAAGGTTTGGCACAAGCCA
TCGTTAATGGTGATGTCCCAGCTGCTATCAAGGATAAAGAAATCATCTCAATTGATATTTCTGCACTTGAAGCTGGTACT
CAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGAAACATTATCCTCTTCTT
CGATGAAATTCATCAAATTCTTGGTGCCGGAAGCACTGGCGATGGTCAAGGTTCTAAAGGTCTGGCTGATATCTTGAAAC
CTGCTCTTTCACGTGGTGAAATAACAGTTATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAGAATGCT
GCCCTTGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTCCTGAAGATACCTTCAAGATTCTTCAAGGTATTCG
TGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGAAGTCTTGAAAGCAGCGGTTGATTTTTCAGTACAATACA
TTCCACAACGTAGCTTGCCAGATAAGGCTATTGACCTTTTGGACATGACAGCAGCTCACTTGGCAGCACAACATCCAGTA
ACTGATGTCAATGCTGTTGAACGTGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGTTGCTAAAGAAGATTACGA
AGCAGCTCTAAATTCTAAGATTCGTATTGAAAAACTTGAAAAGGAAATTGCTAACCATGCAAAAGATCGCAAGGTGACTG
CGACTGTAAACGATGTGGCTGAATCCGTAGAACGTATGACTGGTATTCCAGTATCTCAAATGGGTGCATCGGATATCGAA
CGTTTGAAAGATATGGGTAACCGTTTGCAAGCTAAGGTTATCGGTCAAGATAAGGCCGTTGAAGCAGTGGCACGTTCCAT
CCGTCGTAATCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTGTTGGTA
AAACTGAGTTGGCTAAACAATTGGCCCTTGATTTGTTCGGTACCAAAGATGCTATCATCCGTTTGGACATGTCAGAATAC
AGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGATAATAGTAATACCTTGAC
AGAACGTGTTCGTCGTAACCCTTATTCAATCATCCTTCTTGATGAAATTGAAAAGGCAGACCCTCAAGTTATCACCCTTC
TCCTCCAAGTTTTGGATGATGGCCGTTTGACTGATGGTCAAGGTAATACTGTAAACTTCAAGAACACAGTCATTATCGCA
ACTTCAAACGCTGGCTTTGGTTACGAATCTAACTCGACAGAAGATGCTGATAAACCAGAACTCATGGATCGTTTGAAACC
TTACTTCCGTCCTGAATTCCTTAACCGTTTCGACGCAGTTATTGAGTTCTCACACTTAGATAAGGAGGACCTTTCTAAGA
TTGTCGATCTTATGTTGAATGAAGTTAACAAGACTCTTTCTAAGAAAGGCATTGACTTGGCAGTTAGCGAAGCTGCTAAA
GCCTATATGACAGAAGAAGGCTATGATGAAGTTATGGGTGCTCGTCCACTCCGTCGTGTAGTTGAACAACAAATCCGTGA
CAAAGTCACAGACTTCCACTTGGATAACCTTGATGCAAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTAGTTATCA
AAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (606-676)

• AAA lid domain (AAA_lid_9) (255-349)

• ATPase family associated with various cellular activities (AAA) (AAA) (114-246)

• AAA domain (Cdc48 subfamily) (AAA_2) (439-599)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	46.924	100	0.469
clpC	Lactococcus lactis subsp. cremoris KW2	49.219	91.559	0.451
clpE	Streptococcus pneumoniae D39	48.657	90.558	0.441
clpE	Streptococcus pneumoniae R6	48.657	90.558	0.441
clpE	Streptococcus pneumoniae Rx1	48.657	90.558	0.441
clpE	Streptococcus pneumoniae TIGR4	48.657	90.558	0.441
clpC	Bacillus subtilis subsp. subtilis str. 168	45.975	92.418	0.425
clpC	Streptococcus thermophilus LMD-9	43.26	91.273	0.395
clpC	Streptococcus thermophilus LMG 18311	43.103	91.273	0.393
clpC	Streptococcus pneumoniae TIGR4	43.499	89.127	0.388
clpC	Streptococcus pneumoniae Rx1	43.499	89.127	0.388
clpC	Streptococcus pneumoniae D39	43.499	89.127	0.388
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.598	88.269	0.385
clpC	Streptococcus mutans UA159	43.156	88.841	0.383