Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   H1X63_RS08305 Genome accession   NZ_LR822027
Coordinates   1601638..1602375 (+) Length   245 a.a.
NCBI ID   WP_180487748.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_998     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1596638..1607375
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H1X63_RS08270 (STHERMO_1806) - 1597040..1597219 (-) 180 WP_011681564.1 hypothetical protein -
  H1X63_RS08275 (STHERMO_1807) - 1597248..1597640 (-) 393 WP_084829084.1 hypothetical protein -
  H1X63_RS08280 (STHERMO_1808) cipB 1597652..1597891 (-) 240 WP_021152514.1 Blp family class II bacteriocin Regulator
  H1X63_RS08285 (STHERMO_1809) - 1598477..1598731 (-) 255 WP_179972242.1 Blp family class II bacteriocin -
  H1X63_RS11130 (STHERMO_1810) - 1598982..1599383 (-) 402 WP_011226490.1 hypothetical protein -
  H1X63_RS08290 (STHERMO_1814) - 1600406..1600636 (-) 231 WP_011226494.1 bacteriocin class II family protein -
  H1X63_RS08295 (STHERMO_1815) - 1600992..1601192 (-) 201 WP_011681569.1 hypothetical protein -
  H1X63_RS08300 (STHERMO_1816) - 1601211..1601387 (-) 177 WP_011681570.1 Blp family class II bacteriocin -
  H1X63_RS08305 (STHERMO_1817) comE/blpR 1601638..1602375 (+) 738 WP_180487748.1 LytR/AlgR family response regulator transcription factor Regulator
  H1X63_RS10810 comD/blpH 1602906..1603709 (+) 804 WP_232086251.1 ATP-binding protein Regulator
  H1X63_RS08315 (STHERMO_1819) - 1603727..1603888 (-) 162 WP_011226496.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  H1X63_RS08320 (STHERMO_1820) comB 1603903..1605270 (-) 1368 WP_096811636.1 bacteriocin secretion accessory protein Regulator

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 27993.38 Da        Isoelectric Point: 6.4947

>NTDB_id=1010433 H1X63_RS08305 WP_180487748.1 1601638..1602375(+) (comE/blpR) [Streptococcus thermophilus isolate STH_CIRM_998]
MKIYLLEDNSIQMGRLEDAVVHELMTFGKDLSCVQSFDKPDQLLSAITSNTSDQIFFLDIEIKGEDKKGLDIAKIIRQNN
PYAIIAFVTTHIEFMPQAFGVTAYKYINKTLDEASFRKEIGETIAQVFPINATTTDEFFLYKTESQLINLPMDQILYLST
SDIKHHVHLQTIHTLMDIRANLADFKKIHKKLYPCHRSYIVNTDMIISVNLTNYEATLINGQVLPISRMKIGKIAQIVEE
RGRGC

Nucleotide


Download         Length: 738 bp        

>NTDB_id=1010433 H1X63_RS08305 WP_180487748.1 1601638..1602375(+) (comE/blpR) [Streptococcus thermophilus isolate STH_CIRM_998]
TTGAAGATTTACCTATTAGAAGATAATTCTATTCAGATGGGTCGCTTGGAAGATGCTGTAGTACATGAACTTATGACCTT
CGGAAAAGATCTATCCTGTGTCCAGTCTTTTGACAAACCTGACCAGTTGTTATCAGCTATCACTTCTAATACAAGCGATC
AGATTTTCTTTCTTGATATTGAAATTAAAGGTGAAGATAAGAAGGGACTTGATATTGCTAAAATCATACGTCAAAATAAC
CCTTATGCTATCATTGCCTTTGTCACTACACATATAGAGTTCATGCCTCAAGCTTTTGGCGTTACAGCCTATAAATACAT
CAATAAAACCTTAGATGAAGCTAGCTTTAGAAAAGAAATAGGGGAAACCATTGCTCAAGTCTTCCCTATTAACGCAACTA
CCACGGATGAGTTTTTTCTCTACAAAACAGAGTCTCAATTAATAAACCTTCCTATGGATCAAATTCTATACCTATCCACA
TCAGATATCAAACACCATGTTCACCTCCAGACTATCCATACCCTCATGGATATCCGAGCAAATCTGGCAGACTTTAAAAA
GATACACAAAAAGCTCTACCCATGCCATCGGTCCTATATCGTCAATACAGATATGATTATCTCTGTCAACTTGACCAATT
ATGAAGCTACCTTAATTAATGGTCAAGTCCTACCAATATCCCGTATGAAGATAGGAAAGATTGCACAGATTGTTGAGGAA
AGAGGCAGAGGATGTTAA

Domains

Predicted by InterProScan.

LytTr DNA-binding domain (LytTR)

(146-237)

Response regulator receiver domain (Response_reg)

(26-119)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

36.255

100

0.371