Detailed information NTG1009878

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: H0510_RS07355
• Genome accession: NZ_LR822019
• Coordinates: 1410665..1412764 (-)
• Length: 699 a.a.
• NCBI ID: WP_179966769.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus isolate STH_CIRM_772
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 1405665..1417764

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H0510_RS07325 (STHERMO_1619)	pptA	1405743..1406474 (-)	732	WP_002951673.1	ABC transporter ATP-binding protein	Regulator
H0510_RS07330 (STHERMO_1620)	-	1406539..1406958 (+)	420	WP_011226437.1	HIT family protein	-
H0510_RS07335 (STHERMO_1621)	-	1406955..1407263 (+)	309	WP_179966768.1	hypothetical protein	-
H0510_RS09665 (STHERMO_1622)	-	1407815..1407985 (-)	171	WP_011226439.1	hypothetical protein	-
H0510_RS07345 (STHERMO_1623)	-	1408055..1408690 (-)	636	WP_014727665.1	DUF4230 domain-containing protein	-
H0510_RS09875 (STHERMO_1624)	-	1408709..1408834 (-)	126	WP_260215148.1	hypothetical protein	-
H0510_RS07350 (STHERMO_1625)	-	1409311..1410560 (+)	1250	Protein_1410	ISL3 family transposase	-
H0510_RS07355 (STHERMO_1626)	clpE	1410665..1412764 (-)	2100	WP_179966769.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
H0510_RS07360 (STHERMO_1627)	-	1413479..1414570 (-)	1092	WP_179966770.1	nucleotidyltransferase	-
H0510_RS07365 (STHERMO_1628)	-	1414577..1415317 (-)	741	WP_311316668.1	class I SAM-dependent methyltransferase	-
H0510_RS07370 (STHERMO_1629)	rsfS	1415642..1415995 (-)	354	WP_179966771.1	ribosome silencing factor	-
H0510_RS07375 (STHERMO_1630)	yqeK	1416019..1416609 (-)	591	WP_002951696.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
H0510_RS07380 (STHERMO_1631)	-	1416606..1417238 (-)	633	WP_065972527.1	nicotinate-nucleotide adenylyltransferase	-
H0510_RS07385 (STHERMO_1632)	yhbY	1417342..1417659 (-)	318	WP_002951701.1	ribosome assembly RNA-binding protein YhbY	-

Sequence

Protein

• Length: 699 a.a.
• Molecular weight: 77167.06 Da
• Isoelectric Point: 4.8564

>NTDB_id=1009878 H0510_RS07355 WP_179966769.1 1410665..1412764(-) (clpE) [Streptococcus thermophilus isolate STH_CIRM_772]
MNNNFNNMDDLFNQLMGNMGGFRSESRRYMINGREVTPEEFAIYRQTGKLPGNQGEAVNPTQQHGPKQDGILAKLGRNLT
QEAREGKLDPVIGRNKEIQETSEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKDKEIISIDISALEAGT
QYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGEITVIGATTQDEYRNTILKNA
ALARRFNEVKVNAPSPEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLLDVTAAHLAAQHPV
TDVNAVEREIEEEKAKQEAAVAKEDYEAALNSKIRIEKLEKEIANHAKDRKVTATVNDVAESVERMTGIPVSQMGATDIE
RLKNMGNRLQAKVIGQDKAVEAVARSIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDLFGTKDAIIRLDMSEY
SDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVIIA
TSNAGFGYESNSTEDADKPELMDRLKPYFRPEFLNRFDAVIEFSHLDKEDLSKIVDLMLNEVNKTLSKKGIDLAVSEAAK
AYMTEEGYDEVMGARPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK

Nucleotide

• Length: 2100 bp

>NTDB_id=1009878 H0510_RS07355 WP_179966769.1 1410665..1412764(-) (clpE) [Streptococcus thermophilus isolate STH_CIRM_772]
ATGAACAACAACTTTAATAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTTCCGTTCAGAAAGCCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCAATTTACCGTCAAACAGGTAAATTGCCTGGTAATC
AAGGTGAAGCAGTAAACCCAACGCAACAACACGGACCTAAACAAGATGGTATTCTTGCTAAGCTTGGTCGTAACTTGACT
CAAGAAGCTCGTGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAACTAGCGAAATCTTGGCTCG
TCGTACTAAGAATAACCCAGTCCTTGTCGGTGATGCTGGGGTTGGTAAAACAGCTGTAGTTGAAGGTTTGGCACAAGCCA
TAGTTAATGGTGATGTCCCAGCTGCTATCAAGGACAAAGAAATCATCTCAATTGATATTTCTGCACTTGAAGCTGGTACT
CAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGAAACATTATCCTCTTCTT
CGATGAAATTCATCAAATTCTTGGTGCCGGAAGCACTGGCGATGGTCAAGGTTCTAAAGGTCTGGCTGATATCTTGAAAC
CTGCTCTTTCACGTGGTGAAATAACAGTGATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAGAATGCT
GCCCTTGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTCCTGAAGATACCTTCAAGATTCTTCAAGGTATTCG
TGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTCTTGAAAGCAGCAGTTGATTTTTCAGTACAATACA
TTCCACAACGTAGCTTGCCAGATAAGGCTATTGACCTTTTGGACGTGACAGCAGCTCACTTGGCAGCACAACATCCAGTA
ACTGATGTCAATGCTGTTGAACGTGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGTTGCTAAAGAAGATTACGA
AGCAGCTCTAAATTCTAAGATTCGTATTGAAAAACTTGAAAAGGAAATTGCTAACCATGCAAAAGATCGCAAGGTGACTG
CGACTGTAAACGATGTGGCTGAATCCGTAGAACGTATGACTGGTATTCCAGTATCTCAAATGGGTGCAACGGATATCGAA
CGTTTGAAAAATATGGGTAACCGTTTGCAAGCTAAGGTTATCGGTCAAGATAAGGCCGTTGAAGCAGTGGCACGTTCCAT
CCGTCGTAATCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTGTTGGTA
AAACTGAGTTGGCTAAACAATTGGCCCTTGATTTGTTCGGTACCAAAGATGCTATCATCCGTTTGGACATGTCAGAATAC
AGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGATAATAGTAATACCTTGAC
AGAACGTGTTCGTCGTAACCCTTATTCAATCATCCTTCTTGATGAAATTGAAAAGGCAGACCCTCAAGTTATCACCCTTC
TCCTCCAAGTCTTGGATGATGGCCGTTTGACTGATGGTCAAGGTAATACTGTAAACTTCAAGAACACAGTCATTATCGCA
ACTTCAAACGCTGGCTTTGGTTACGAATCTAACTCGACAGAAGATGCTGATAAACCAGAACTCATGGATCGTTTGAAACC
TTACTTCCGTCCTGAATTCCTTAACCGTTTCGACGCAGTTATTGAGTTCTCACACTTAGATAAGGAGGACCTTTCTAAGA
TTGTCGATCTTATGTTGAATGAAGTTAACAAGACTCTTTCTAAGAAAGGCATTGACTTGGCAGTTAGCGAAGCTGCTAAA
GCCTATATGACAGAAGAAGGCTATGATGAAGTTATGGGTGCTCGTCCACTCCGTCGTGTAGTTGAACAACAAATCCGTGA
CAAAGTCACAGACTTCCACTTGGATAACCTTGATGCAAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTAGTTATCA
AAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (439-599)

• ATPase family associated with various cellular activities (AAA) (AAA) (114-246)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (606-676)

• AAA lid domain (AAA_lid_9) (255-349)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	46.781	100	0.468
clpC	Lactococcus lactis subsp. cremoris KW2	49.219	91.559	0.451
clpE	Streptococcus pneumoniae D39	48.657	90.558	0.441
clpE	Streptococcus pneumoniae Rx1	48.657	90.558	0.441
clpE	Streptococcus pneumoniae R6	48.657	90.558	0.441
clpE	Streptococcus pneumoniae TIGR4	48.576	90.415	0.439
clpC	Bacillus subtilis subsp. subtilis str. 168	46.285	92.418	0.428
clpC	Streptococcus thermophilus LMD-9	43.417	91.273	0.396
clpC	Streptococcus thermophilus LMG 18311	43.26	91.273	0.395
clpC	Streptococcus pneumoniae TIGR4	43.499	89.127	0.388
clpC	Streptococcus pneumoniae Rx1	43.499	89.127	0.388
clpC	Streptococcus pneumoniae D39	43.499	89.127	0.388
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.436	88.269	0.383
clpC	Streptococcus mutans UA159	43.156	88.841	0.383