Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   H0506_RS09760 Genome accession   NZ_LR822015
Coordinates   1482016..1482819 (+) Length   267 a.a.
NCBI ID   WP_224103634.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_65     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1477016..1487819
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0506_RS10005 - 1478388..1478629 (-) 242 Protein_1451 Blp family class II bacteriocin -
  H0506_RS10010 (STHERMO_1698) - 1478880..1479281 (-) 402 WP_011226490.1 hypothetical protein -
  H0506_RS07665 (STHERMO_1702) - 1480268..1480498 (-) 231 WP_011226494.1 bacteriocin class II family protein -
  H0506_RS07670 (STHERMO_1703) - 1480748..1481479 (+) 732 WP_011226495.1 LytTR family DNA-binding domain-containing protein -
  H0506_RS09760 comD/blpH 1482016..1482819 (+) 804 WP_224103634.1 ATP-binding protein Regulator
  H0506_RS07680 (STHERMO_1705) - 1482837..1482998 (-) 162 WP_011226496.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  H0506_RS07685 (STHERMO_1706) - 1483013..1484381 (-) 1369 Protein_1457 bacteriocin secretion accessory protein -
  H0506_RS07690 (STHERMO_1709) comA/nlmT 1484397..1486550 (-) 2154 WP_041828330.1 peptide cleavage/export ABC transporter Regulator

Sequence

Protein


Download         Length: 267 a.a.        Molecular weight: 30835.17 Da        Isoelectric Point: 4.8309

>NTDB_id=1009702 H0506_RS09760 WP_224103634.1 1482016..1482819(+) (comD/blpH) [Streptococcus thermophilus isolate STH_CIRM_65]
MYLENTTHSSTLELRKLCVVISLVLFFIMIVFLERNIREMIQGQLDFQKNLQLENLYTYNKHIECLYNSVRSFRHDYSNL
LVTLRLGIDKDDMDIVKEVYDSVLQESDKRLNTRNFDLARLVNIQDNTLKSLLSAKVLQAEEEGIEAQISIPEPIHLIGM
EILDFIIVTSIFLDNAIEGAIQTQNHKITISFWEDHRSQLLSISNTISEEQTETKTIFERGVSNKGRERGIGLANVTEIL
DNYINVNLETQSNNFSFTQQLTITKKA

Nucleotide


Download         Length: 804 bp        

>NTDB_id=1009702 H0506_RS09760 WP_224103634.1 1482016..1482819(+) (comD/blpH) [Streptococcus thermophilus isolate STH_CIRM_65]
ATGTATCTTGAAAACACTACTCACTCTTCAACTTTGGAGCTTCGAAAACTCTGTGTTGTTATTTCACTTGTCCTCTTCTT
CATTATGATTGTCTTTTTAGAAAGAAACATTCGTGAAATGATTCAAGGACAATTGGACTTCCAGAAAAATCTCCAGCTAG
AGAATCTCTACACCTACAATAAACATATTGAATGTCTCTACAATTCTGTTCGTAGTTTTAGACACGATTATAGTAATCTC
TTAGTCACATTACGATTGGGGATAGATAAAGACGATATGGATATTGTCAAAGAAGTCTATGATAGTGTGCTTCAAGAATC
CGATAAACGATTAAATACAAGAAACTTTGACTTAGCTAGACTCGTTAATATTCAGGATAATACTTTGAAAAGCCTTCTGT
CCGCAAAAGTTTTACAAGCAGAAGAAGAAGGTATTGAAGCTCAGATTAGCATCCCAGAACCCATCCACTTGATTGGGATG
GAGATTCTGGACTTCATTATCGTCACTTCTATTTTTTTAGATAACGCTATTGAAGGTGCCATTCAAACTCAAAACCATAA
AATTACTATTAGCTTTTGGGAAGATCATCGTTCACAGCTATTATCTATTAGCAATACCATAAGTGAAGAACAAACAGAAA
CTAAAACCATATTTGAAAGAGGTGTCTCCAACAAGGGACGAGAGCGAGGCATTGGCCTTGCTAATGTCACAGAAATCTTA
GATAACTATATCAATGTAAACTTAGAAACACAGAGTAACAATTTCTCATTCACACAACAATTAACAATAACTAAAAAGGC
CTAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(160-263)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

38.189

95.131

0.363

Multiple sequence alignment