Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGH   Type   Machinery gene
Locus tag   H0506_RS08495 Genome accession   NZ_LR822015
Coordinates   1644889..1645845 (-) Length   318 a.a.
NCBI ID   WP_011226622.1    Uniprot ID   Q5M2G5
Organism   Streptococcus thermophilus isolate STH_CIRM_65     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1639889..1650845
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0506_RS08465 (STHERMO_1888) proC 1640439..1641209 (+) 771 WP_011226616.1 pyrroline-5-carboxylate reductase -
  H0506_RS08470 (STHERMO_1889) - 1641239..1641901 (-) 663 WP_179971686.1 CPBP family intramembrane glutamic endopeptidase -
  H0506_RS08475 (STHERMO_1891) - 1642004..1642452 (-) 449 Protein_1612 CAAX protease -
  H0506_RS09815 (STHERMO_1892) - 1642526..1642951 (-) 426 WP_041827107.1 CPBP family intramembrane glutamic endopeptidase -
  H0506_RS08485 (STHERMO_1894) - 1643194..1643391 (-) 198 WP_011681682.1 helix-turn-helix transcriptional regulator -
  H0506_RS08490 (STHERMO_1895) - 1643640..1644833 (-) 1194 WP_022096898.1 acetate kinase -
  H0506_RS08495 (STHERMO_1896) comGH 1644889..1645845 (-) 957 WP_011226622.1 class I SAM-dependent methyltransferase Machinery gene
  H0506_RS08500 (STHERMO_1897) comGG 1645890..1646207 (-) 318 WP_011226623.1 competence type IV pilus minor pilin ComGG Machinery gene
  H0506_RS08505 (STHERMO_1898) comGF 1646185..1646622 (-) 438 WP_014608742.1 competence type IV pilus minor pilin ComGF Machinery gene
  H0506_RS08510 (STHERMO_1899) comGE 1646606..1646899 (-) 294 WP_011226625.1 competence type IV pilus minor pilin ComGE Machinery gene
  H0506_RS08515 (STHERMO_1900) comGD 1646871..1647299 (-) 429 WP_011226626.1 competence type IV pilus minor pilin ComGD Machinery gene
  H0506_RS08520 (STHERMO_1901) comGC 1647259..1647585 (-) 327 WP_002946126.1 competence type IV pilus major pilin ComGC Machinery gene
  H0506_RS08525 (STHERMO_1902) comGB 1647582..1648682 (-) 1101 WP_148148900.1 competence type IV pilus assembly protein ComGB Machinery gene
  H0506_RS08530 (STHERMO_1903) comGA/cglA/cilD 1648564..1649505 (-) 942 WP_011226629.1 competence type IV pilus ATPase ComGA Machinery gene
  H0506_RS08535 (STHERMO_1904) - 1649586..1649948 (-) 363 WP_011226630.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 318 a.a.        Molecular weight: 35857.00 Da        Isoelectric Point: 4.7123

>NTDB_id=1009689 H0506_RS08495 WP_011226622.1 1644889..1645845(-) (comGH) [Streptococcus thermophilus isolate STH_CIRM_65]
MNFEAIETAFELLLENVQTIENDLGTHAYDALIEQNSYYLGAEVANELIIKNNEKLRALNLSKEEWRRAFQFLFIKLGQL
EALQANHQFTPDAIGFIILYLLEGLTQEKQLDILEIGSGTGNLAETLLNNSQKTLNYMGMEVDDLLIDLSASIAEVVNSV
AVYIQGDAVRPHILKESNVIISDLPIGYYPNDEIASRFKVAATGEHTYAHHLLMEQSLKYLKKDGIAIFLAPTNLLTSPQ
SDLLKKWLSGYADIIAVITLPEAAFGNKHNMKSIFVLKKQTKNAPETFVYPLSDLQNPRILKDFTENFQKWKSDNSIF

Nucleotide


Download         Length: 957 bp        

>NTDB_id=1009689 H0506_RS08495 WP_011226622.1 1644889..1645845(-) (comGH) [Streptococcus thermophilus isolate STH_CIRM_65]
ATGAATTTTGAAGCAATTGAGACAGCTTTTGAGCTGTTGTTAGAAAATGTCCAAACTATTGAAAATGATCTTGGAACCCA
TGCTTACGATGCACTTATTGAGCAAAATTCCTATTATTTGGGGGCTGAGGTTGCTAATGAGCTCATCATCAAAAACAACG
AGAAATTACGGGCGCTTAATCTAAGTAAAGAGGAGTGGCGTCGTGCTTTTCAGTTTTTGTTTATCAAACTAGGGCAATTG
GAAGCTTTACAAGCCAATCACCAATTTACACCAGATGCTATCGGATTTATCATTCTGTACTTGCTCGAAGGTTTGACCCA
GGAAAAACAATTAGATATCTTGGAGATTGGTTCGGGAACAGGAAACTTGGCTGAAACTCTTCTAAATAATAGTCAGAAAA
CCCTTAATTATATGGGGATGGAAGTTGATGATCTTCTTATCGATTTGTCAGCTAGTATTGCTGAGGTGGTGAATTCAGTA
GCGGTTTATATCCAAGGGGATGCTGTTCGACCACATATTCTCAAAGAGAGCAACGTTATTATCAGCGATTTACCTATAGG
TTACTACCCTAATGATGAGATTGCGAGTCGTTTCAAGGTGGCAGCAACTGGCGAACACACTTATGCCCATCATCTTCTTA
TGGAGCAATCGCTTAAGTATTTGAAGAAAGATGGTATTGCTATTTTTTTGGCACCAACCAATCTTTTGACAAGCCCTCAA
AGTGATCTGCTTAAGAAGTGGTTATCAGGATATGCTGATATTATTGCTGTTATTACTCTTCCAGAAGCAGCTTTTGGCAA
TAAACATAACATGAAGTCTATCTTTGTGCTAAAAAAACAAACTAAAAATGCTCCTGAGACCTTCGTTTACCCACTTAGCG
ATTTGCAAAATCCAAGGATCCTCAAGGATTTTACAGAGAATTTCCAAAAATGGAAATCAGATAATTCCATTTTCTAG

Domains

Predicted by InterProScan.

N-6 DNA Methylase (N6_Mtase)

(69-291)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5M2G5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGH Streptococcus mutans UA159

68.889

99.057

0.682
  comGH Streptococcus mutans UA140

68.889

99.057

0.682