Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   ABK447_RS14775 Genome accession   NZ_CP157943
Coordinates   2964908..2965564 (-) Length   218 a.a.
NCBI ID   WP_003155032.1    Uniprot ID   I2C3J8
Organism   Bacillus sp. hwrm1     
Function   degradation of ComK (predicted from homology)   
Competence regulation

Genomic Context

Location: 2959908..2970564
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABK447_RS14755 (ABK447_14745) spxH 2960147..2961049 (+) 903 WP_032874464.1 protease adaptor protein SpxH -
  ABK447_RS14760 (ABK447_14750) - 2961335..2961502 (+) 168 WP_003155026.1 hypothetical protein -
  ABK447_RS14765 (ABK447_14755) pepF 2961540..2963369 (-) 1830 WP_094031915.1 oligoendopeptidase F Regulator
  ABK447_RS14770 (ABK447_14760) - 2963597..2964757 (-) 1161 WP_069006905.1 competence protein CoiA family protein -
  ABK447_RS14775 (ABK447_14765) mecA 2964908..2965564 (-) 657 WP_003155032.1 adaptor protein MecA Regulator
  ABK447_RS14780 (ABK447_14770) - 2965547..2965657 (-) 111 Protein_2920 adaptor protein MecA -
  ABK447_RS14785 (ABK447_14775) - 2965840..2966496 (+) 657 WP_015239570.1 TerC family protein -
  ABK447_RS14790 (ABK447_14780) spx 2966554..2966949 (-) 396 WP_003155034.1 transcriptional regulator Spx -
  ABK447_RS14795 (ABK447_14785) - 2967128..2967706 (-) 579 WP_007409110.1 GNAT family N-acetyltransferase -
  ABK447_RS14800 (ABK447_14790) - 2967824..2969011 (-) 1188 WP_015239569.1 putative glycoside hydrolase -
  ABK447_RS14805 (ABK447_14795) oppF 2969118..2970035 (-) 918 WP_015239568.1 oligopeptide ABC transporter ATP-binding protein OppF -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 25964.75 Da        Isoelectric Point: 4.1143

>NTDB_id=1009201 ABK447_RS14775 WP_003155032.1 2964908..2965564(-) (mecA) [Bacillus sp. hwrm1]
MEIERINEHTVKFYMSYGDIEDRGFDREEIWYNRERSEELFWEVMDEVHDEEEFAVEGPLWIQVQALDKGLEIIVTKAQL
SKDGQKLELPIPEDKKQEPADENLDALLDDFQKEEQAESREDKEQKLQFTLRFDDFEDLISLSKLNLNGIKTTLYSFEDR
YYLYADFYEQTDEEVENQLSILLEYAHESSVSIHRLEEYGKLVIADHALYTIKKHFAS

Nucleotide


Download         Length: 657 bp        

>NTDB_id=1009201 ABK447_RS14775 WP_003155032.1 2964908..2965564(-) (mecA) [Bacillus sp. hwrm1]
ATGGAAATAGAAAGAATTAATGAGCATACTGTAAAATTTTATATGTCTTATGGTGATATTGAAGATCGCGGTTTTGACAG
AGAAGAAATCTGGTACAATCGCGAGCGCAGTGAAGAACTGTTCTGGGAAGTCATGGATGAAGTGCATGATGAAGAGGAAT
TCGCTGTCGAGGGTCCTCTTTGGATTCAGGTTCAGGCATTGGACAAAGGACTGGAAATAATCGTAACAAAAGCCCAGCTT
TCCAAGGATGGACAAAAACTCGAACTGCCGATCCCGGAAGATAAAAAACAAGAGCCGGCAGATGAAAATCTCGATGCTTT
ACTTGATGATTTCCAGAAAGAAGAGCAGGCCGAGAGCCGGGAAGATAAGGAGCAAAAGCTTCAGTTCACTTTGCGGTTCG
ATGATTTTGAGGATCTCATCTCGCTATCAAAATTGAATCTTAACGGAATCAAAACGACCCTGTATTCGTTTGAAGACCGA
TATTATTTATATGCAGATTTTTATGAGCAAACTGATGAAGAGGTTGAAAATCAGCTAAGCATCCTGTTGGAGTACGCGCA
CGAATCATCAGTCAGCATTCACCGTCTTGAAGAATACGGCAAATTGGTGATCGCTGATCATGCGTTATATACAATAAAAA
AACACTTTGCATCATAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2C3J8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Bacillus subtilis subsp. subtilis str. 168

89.45

100

0.895

Multiple sequence alignment