Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   H0501_RS07680 Genome accession   NZ_LR822008
Coordinates   1490692..1492797 (-) Length   701 a.a.
NCBI ID   WP_179970588.1    Uniprot ID   -
Organism   Streptococcus thermophilus isolate STH_CIRM_18     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1485692..1497797
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H0501_RS07650 (STHERMO_1697) pptB 1486150..1487184 (-) 1035 WP_414487301.1 ABC transporter permease Regulator
  H0501_RS07655 (STHERMO_1698) pptA 1487184..1487915 (-) 732 WP_002951673.1 ABC transporter ATP-binding protein Regulator
  H0501_RS07660 (STHERMO_1699) - 1487980..1488399 (+) 420 WP_011681530.1 HIT family protein -
  H0501_RS07665 (STHERMO_1700) - 1488396..1488704 (+) 309 WP_014608635.1 hypothetical protein -
  H0501_RS07670 (STHERMO_1701) - 1488746..1489477 (-) 732 WP_014608636.1 hypothetical protein -
  H0501_RS07675 (STHERMO_1702) - 1489496..1490131 (-) 636 WP_014727665.1 DUF4230 domain-containing protein -
  H0501_RS10295 - 1490150..1490275 (-) 126 WP_011681534.1 hypothetical protein -
  H0501_RS07680 (STHERMO_1703) clpC 1490692..1492797 (-) 2106 WP_179970588.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  H0501_RS07685 (STHERMO_1704) - 1493512..1494603 (-) 1092 WP_179970587.1 nucleotidyltransferase -
  H0501_RS07690 (STHERMO_1705) - 1494610..1495350 (-) 741 WP_301280230.1 class I SAM-dependent DNA methyltransferase -
  H0501_RS07695 (STHERMO_1706) rsfS 1495675..1496028 (-) 354 WP_011227491.1 ribosome silencing factor -
  H0501_RS07700 (STHERMO_1707) yqeK 1496052..1496642 (-) 591 WP_095559432.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  H0501_RS07705 (STHERMO_1708) - 1496639..1497271 (-) 633 WP_082309109.1 nicotinate-nucleotide adenylyltransferase -
  H0501_RS07710 (STHERMO_1709) yhbY 1497375..1497692 (-) 318 WP_002951701.1 ribosome assembly RNA-binding protein YhbY -

Sequence

Protein


Download         Length: 701 a.a.        Molecular weight: 77329.20 Da        Isoelectric Point: 4.7951

>NTDB_id=1008958 H0501_RS07680 WP_179970588.1 1490692..1492797(-) (clpC) [Streptococcus thermophilus isolate STH_CIRM_18]
MNNNFNNMDDLFNQLMGNMGGFRSESRRYMINGREVTPEEFAIYRQTGKLPGNQGEAVNPTQQQGNGPKQDGILAKIGRN
LTQEAREGKLDPVIGRNKEIQETSEILARRTKNNPVLVGDAGVGKTAVVEGLAQAIVSGDVPAAIKDKEIISIDISALEA
GTQYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGEITVIGATTQDEYRNTILK
NPALARRFNEVKVNAPSPEDTFKILQGIRDLYEKHHNVILPDDVLKAAVDFSVQYIPQRSLPDKAIDLLDVTAAHLAAQH
PVTDVNAVEREIEEEKAKQEAAVAKEDYEAALNSKIRIEKLEKEIANHAKDRKVTATVNDVAESVERMTGIPVSQMGATD
IERLKDMGNRLQAKVIGQDKAVEAVARSIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDLFGTKDAIIRLDMS
EYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIILLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTVI
IATSNAGFGYESNSTEDADKPELMDRLKPYFRPEFLNRFDAVIEFSHLDKEDLSKIVDLMLNEVNKTLSKKGIDLAVSEA
AKAYMTEEGYDEVMGARPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGVLVIKEKDAK

Nucleotide


Download         Length: 2106 bp        

>NTDB_id=1008958 H0501_RS07680 WP_179970588.1 1490692..1492797(-) (clpC) [Streptococcus thermophilus isolate STH_CIRM_18]
ATGAACAACAACTTTAATAATATGGATGATCTTTTCAATCAATTGATGGGTAACATGGGTGGTTTCCGTTCAGAAAGCCG
TCGCTACATGATTAACGGTCGTGAAGTGACACCTGAAGAATTTGCAATTTACCGTCAAACAGGTAAATTGCCTGGTAATC
AAGGTGAAGCAGTGAACCCAACGCAACAACAGGGTAACGGACCTAAACAAGATGGTATTCTTGCTAAAATTGGTCGTAAC
TTGACTCAAGAAGCTCGTGAAGGTAAATTGGATCCTGTTATCGGACGTAACAAAGAAATCCAAGAAACTAGCGAAATCTT
GGCTCGTCGTACTAAGAATAACCCAGTCCTTGTCGGTGATGCTGGGGTTGGTAAAACAGCTGTAGTTGAAGGTTTGGCAC
AAGCCATCGTTAGTGGTGATGTCCCAGCTGCTATCAAGGACAAAGAAATCATCTCAATTGATATTTCTGCACTTGAAGCT
GGTACTCAATACCGTGGTAGCTTTGAAGAAAACATTCAAAACTTGGTAAATGAAGTCAAAGAAGCTGGAAACATTATCCT
CTTCTTCGATGAAATTCATCAAATTCTTGGTGCCGGAAGCACTGGCGATGGTCAAGGTTCTAAAGGTCTGGCTGATATCT
TGAAACCTGCTCTTTCACGTGGTGAAATAACAGTGATTGGTGCAACAACTCAAGATGAATACCGTAACACTATCTTGAAG
AATCCTGCCCTTGCTCGTCGTTTCAACGAAGTTAAGGTCAATGCTCCTTCTCCTGAAGATACCTTCAAGATTCTTCAAGG
TATTCGTGATCTTTATGAAAAACACCACAATGTTATCTTGCCAGATGATGTCTTGAAAGCAGCGGTTGATTTTTCAGTAC
AATACATTCCACAACGTAGCTTGCCAGATAAGGCTATTGACCTTTTGGACGTGACAGCAGCTCACTTGGCAGCACAACAT
CCAGTAACTGATGTCAATGCTGTTGAACGTGAAATCGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGTTGCTAAAGAAGA
TTACGAAGCAGCTCTAAATTCTAAGATTCGTATTGAAAAACTTGAAAAGGAAATTGCTAACCATGCAAAAGATCGCAAGG
TGACTGCGACTGTAAACGATGTGGCTGAATCTGTAGAACGTATGACTGGTATTCCAGTATCTCAAATGGGTGCAACGGAT
ATCGAACGTTTGAAAGATATGGGTAACCGTTTGCAAGCTAAGGTTATCGGTCAAGATAAGGCCGTTGAAGCAGTGGCACG
TTCCATCCGTCGTAATCGTGCAGGATTTGACGAAGGTAACCGTCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTGGTG
TTGGTAAAACTGAGTTGGCTAAACAATTGGCCCTTGATTTGTTCGGTACCAAAGATGCTATCATCCGTTTGGACATGTCA
GAATACAGCGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGATAATAGTAATAC
CTTGACAGAACGTGTTCGTCGTAACCCTTATTCAATCATCCTTCTTGATGAAATTGAAAAGGCAGACCCTCAAGTTATCA
CCCTTCTCCTCCAAGTTTTGGATGATGGCCGTTTGACTGATGGTCAAGGTAATACTGTAAACTTCAAGAACACAGTCATT
ATCGCAACTTCAAACGCTGGCTTTGGTTACGAATCTAACTCGACAGAAGATGCTGATAAACCAGAACTCATGGATCGTTT
GAAACCTTACTTCCGTCCTGAATTCCTTAACCGTTTCGACGCAGTTATTGAGTTCTCACACTTAGATAAGGAGGACCTTT
CTAAGATTGTCGATCTTATGTTGAATGAAGTTAACAAGACTCTTTCTAAGAAAGGCATTGACTTGGCAGTTAGCGAAGCT
GCTAAAGCCTATATGACAGAAGAAGGCTATGATGAAGTTATGGGTGCTCGTCCACTCCGTCGTGTAGTTGAACAACAAAT
CCGTGACAAAGTCACAGACTTCCACTTGGATAACCTTGATGCAAAACACCTAGAAGCTGATATGGAAGATGGTGTCTTAG
TTATCAAAGAAAAAGATGCTAAATAA

Domains

Predicted by InterProScan.

ATPase family associated with various cellular activities (AAA) (AAA)

(116-235)

AAA lid domain (AAA_lid_9)

(257-351)

AAA domain (Cdc48 subfamily) (AAA_2)

(441-601)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(608-678)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Lactococcus lactis subsp. cremoris KW2

48.848

92.867

0.454
  clpE Streptococcus mutans UA159

49.377

91.583

0.452
  clpE Streptococcus pneumoniae D39

47.975

91.583

0.439
  clpE Streptococcus pneumoniae Rx1

47.975

91.583

0.439
  clpE Streptococcus pneumoniae R6

47.975

91.583

0.439
  clpE Streptococcus pneumoniae TIGR4

47.894

91.441

0.438
  clpC Bacillus subtilis subsp. subtilis str. 168

44.962

94.864

0.427
  clpC Streptococcus thermophilus LMD-9

44.084

88.017

0.388
  clpC Streptococcus thermophilus LMG 18311

43.922

88.017

0.387
  clpC Streptococcus pneumoniae TIGR4

43.339

88.873

0.385
  clpC Streptococcus pneumoniae Rx1

43.339

88.873

0.385
  clpC Streptococcus pneumoniae D39

43.339

88.873

0.385
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

43.112

88.017

0.379
  clpC Streptococcus mutans UA159

42.834

88.588

0.379

Multiple sequence alignment