Detailed information NTG1008239

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: UXQ74_RS13190
• Genome accession: NZ_CP157771
• Coordinates: 2645233..2646120 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain BSN117
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2640233..2651120

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXQ74_RS13160 (UXQ74_13160)	-	2640251..2640343 (+)	93	WP_010956583.1	hypothetical protein	-
UXQ74_RS13165 (UXQ74_13165)	-	2640451..2640948 (-)	498	WP_001065269.1	glutathione peroxidase	-
UXQ74_RS13170 (UXQ74_13170)	-	2640958..2641218 (-)	261	WP_001789910.1	hypothetical protein	-
UXQ74_RS13175 (UXQ74_13175)	-	2641600..2641713 (-)	114	Protein_2556	hypothetical protein	-
UXQ74_RS13180 (UXQ74_13180)	-	2642372..2644372 (-)	2001	WP_000776739.1	ABC transporter permease	-
UXQ74_RS13185 (UXQ74_13185)	-	2644369..2645124 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
UXQ74_RS13190 (UXQ74_13190)	braS	2645233..2646120 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
UXQ74_RS13195 (UXQ74_13195)	braR	2646131..2646796 (-)	666	WP_000697879.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
UXQ74_RS13200 (UXQ74_13200)	-	2646822..2647022 (-)	201	WP_000604727.1	hypothetical protein	-
UXQ74_RS13205 (UXQ74_13205)	-	2647220..2648644 (+)	1425	WP_000953762.1	alkaline phosphatase	-
UXQ74_RS13210 (UXQ74_13210)	-	2648704..2648805 (-)	102	WP_000731972.1	SE2200 family small protein	-
UXQ74_RS13215 (UXQ74_13215)	-	2648927..2649382 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
UXQ74_RS13220 (UXQ74_13220)	-	2649627..2650388 (-)	762	WP_000323447.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=1008239 UXQ74_RS13190 WP_000143420.1 2645233..2646120(-) (braS) [Staphylococcus aureus strain BSN117]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=1008239 UXQ74_RS13190 WP_000143420.1 2645233..2646120(-) (braS) [Staphylococcus aureus strain BSN117]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993