Detailed information NTG1008233

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: UXQ74_RS09310
• Genome accession: NZ_CP157771
• Coordinates: 1904185..1905228 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN117
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1899185..1910228

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXQ74_RS09280 (UXQ74_09280)	-	1899607..1900863 (-)	1257	WP_001789555.1	aminopeptidase	-
UXQ74_RS09285 (UXQ74_09285)	-	1900866..1901066 (-)	201	WP_000180460.1	DUF1128 family protein	-
UXQ74_RS09290 (UXQ74_09290)	-	1901213..1901677 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
UXQ74_RS09295 (UXQ74_09295)	-	1901684..1901959 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
UXQ74_RS09300 (UXQ74_09300)	-	1902237..1903454 (+)	1218	WP_000037079.1	YihY/virulence factor BrkB family protein	-
UXQ74_RS09305 (UXQ74_09305)	vraR	1903566..1904195 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
UXQ74_RS09310 (UXQ74_09310)	vraS	1904185..1905228 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
UXQ74_RS09315 (UXQ74_09315)	liaF	1905225..1905926 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
UXQ74_RS09320 (UXQ74_09320)	-	1905941..1906327 (-)	387	WP_001110179.1	hypothetical protein	-
UXQ74_RS09325 (UXQ74_09325)	map	1906544..1907302 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
UXQ74_RS09330 (UXQ74_09330)	-	1907830..1908816 (+)	987	WP_000999714.1	aromatic acid exporter family protein	-
UXQ74_RS09335 (UXQ74_09335)	-	1909247..1909660 (-)	414	WP_025173836.1	hypothetical protein	-
UXQ74_RS09340 (UXQ74_09340)	-	1909689..1909799 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1008233 UXQ74_RS09310 WP_001017131.1 1904185..1905228(-) (vraS) [Staphylococcus aureus strain BSN117]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1008233 UXQ74_RS09310 WP_001017131.1 1904185..1905228(-) (vraS) [Staphylococcus aureus strain BSN117]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1