Detailed information NTG1008191

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: UXQ72_RS09485
• Genome accession: NZ_CP157769
• Coordinates: 1920036..1921079 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain BSN118
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1915036..1926079

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
UXQ72_RS09455 (UXQ72_009455)	-	1915457..1916704 (-)	1248	WP_000656302.1	aminopeptidase	-
UXQ72_RS09460 (UXQ72_009460)	-	1916716..1916916 (-)	201	WP_000180459.1	DUF1128 family protein	-
UXQ72_RS09465 (UXQ72_009465)	-	1917063..1917527 (+)	465	WP_000228668.1	low molecular weight protein-tyrosine-phosphatase	-
UXQ72_RS09470 (UXQ72_009470)	-	1917534..1917809 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
UXQ72_RS09475 (UXQ72_009475)	-	1918087..1919304 (+)	1218	WP_000037083.1	YihY/virulence factor BrkB family protein	-
UXQ72_RS09480 (UXQ72_009480)	vraR	1919417..1920046 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
UXQ72_RS09485 (UXQ72_009485)	vraS	1920036..1921079 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
UXQ72_RS09490 (UXQ72_009490)	liaF	1921076..1921777 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
UXQ72_RS09495 (UXQ72_009495)	-	1921792..1922178 (-)	387	WP_049296041.1	hypothetical protein	-
UXQ72_RS09500 (UXQ72_009500)	map	1922395..1923153 (-)	759	WP_000636137.1	type I methionyl aminopeptidase	-
UXQ72_RS09505 (UXQ72_009505)	-	1923684..1924670 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
UXQ72_RS09510 (UXQ72_009510)	-	1924848..1925261 (-)	414	WP_001622129.1	hypothetical protein	-
UXQ72_RS09515 (UXQ72_009515)	-	1925290..1925399 (-)	110	Protein_1838	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=1008191 UXQ72_RS09485 WP_001017131.1 1920036..1921079(-) (vraS) [Staphylococcus aureus strain BSN118]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=1008191 UXQ72_RS09485 WP_001017131.1 1920036..1921079(-) (vraS) [Staphylococcus aureus strain BSN118]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGTTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTACCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTCGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1