Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   ABKJ27_RS05755 Genome accession   NZ_CP157578
Coordinates   1243360..1245618 (+) Length   752 a.a.
NCBI ID   WP_410011501.1    Uniprot ID   -
Organism   Streptococcus sp. KHUD_011     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1238360..1250618
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ABKJ27_RS05725 (ABKJ27_05740) - 1239075..1239260 (+) 186 WP_001068557.1 hypothetical protein -
  ABKJ27_RS05730 (ABKJ27_05745) - 1239284..1240135 (-) 852 WP_410011499.1 NAD(P)H-hydrate dehydratase -
  ABKJ27_RS05735 (ABKJ27_05750) - 1240276..1241133 (-) 858 WP_410011500.1 bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase -
  ABKJ27_RS05740 (ABKJ27_05755) - 1241289..1242023 (-) 735 WP_101782174.1 amino acid ABC transporter ATP-binding protein -
  ABKJ27_RS05745 (ABKJ27_05760) - 1242023..1242706 (-) 684 WP_033676806.1 amino acid ABC transporter permease -
  ABKJ27_RS05750 (ABKJ27_05765) - 1242899..1243129 (+) 231 WP_000443570.1 DUF1797 family protein -
  ABKJ27_RS05755 (ABKJ27_05770) clpE 1243360..1245618 (+) 2259 WP_410011501.1 AAA family ATPase Regulator
  ABKJ27_RS05760 (ABKJ27_05775) - 1245748..1246200 (+) 453 WP_410011502.1 NUDIX hydrolase -
  ABKJ27_RS05765 (ABKJ27_05780) - 1246259..1246558 (+) 300 WP_000767189.1 DUF1827 family protein -
  ABKJ27_RS05770 (ABKJ27_05785) - 1246692..1247324 (+) 633 WP_410011503.1 GNAT family N-acetyltransferase -
  ABKJ27_RS05775 (ABKJ27_05790) ezrA 1247372..1249099 (-) 1728 WP_410011504.1 septation ring formation regulator EzrA -

Sequence

Protein


Download         Length: 752 a.a.        Molecular weight: 83759.24 Da        Isoelectric Point: 5.4541

>NTDB_id=1007464 ABKJ27_RS05755 WP_410011501.1 1243360..1245618(+) (clpE) [Streptococcus sp. KHUD_011]
MLCQNCKINDSTIHLYTNLNGKQKQIDLCQNCYKIIKTDPNNSLFKGMTDLNNRDFDPFGDFFNDLNNFRPSNNTPPTPP
TQSGGGYGGNGGYGSQNRGPAQTPPPSQEKGLLEEFGINVTEIARRGDIDPVIGRDDEIIRVIEILNRRTKNNPVLIGEP
GVGKTAVVEGLAQKIVDGDVPHKLQGKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRKREDIILFIDEIHEIVGAGSA
GDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVQYTDAA
IEAAATLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKSQATREEDFEKAAYFRDQIAKYKEM
QKKKVTDQDTPIISEKTIEHIIEQKTNIPVGDLKEKEQSQLIHLAEDLKSHVIGQDDAVDKIAKAIRRNRVGLGTPNRPI
GSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDESGQLTEKVRRNPYSLILLDE
VEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDAIIIMTSNAGTGKAEASVGFGAAREGRTNSVLGELGNFFSPEFMNRF
DGIIEFKALSKDNLLQIVELMLADVNKRLSSNNIHLDVTDKVKEKLVDLGYDPKMGARPLRRTIQDYIEDAITDFYLENP
SEKDLKAVMTSKGNIQIKSAKKAKVKTSEKEV

Nucleotide


Download         Length: 2259 bp        

>NTDB_id=1007464 ABKJ27_RS05755 WP_410011501.1 1243360..1245618(+) (clpE) [Streptococcus sp. KHUD_011]
ATGCTTTGTCAAAACTGTAAAATCAACGACTCAACAATTCATCTTTATACCAATCTCAATGGAAAACAAAAACAAATTGA
CCTCTGTCAAAACTGCTATAAGATTATCAAAACAGATCCTAACAATAGCCTCTTTAAAGGTATGACAGATTTGAATAATC
GTGACTTTGATCCTTTTGGCGATTTCTTCAATGATTTAAACAATTTTAGACCTTCTAACAACACTCCTCCCACTCCTCCA
ACCCAATCAGGTGGAGGTTACGGTGGAAATGGCGGTTATGGTTCTCAAAATCGTGGGCCTGCCCAAACTCCGCCACCTAG
CCAAGAAAAAGGCCTGCTGGAAGAATTTGGTATCAACGTAACTGAAATTGCCCGTCGTGGAGATATTGACCCTGTTATTG
GACGCGACGATGAAATTATCCGTGTCATCGAAATTCTCAATCGTAGAACCAAGAATAATCCTGTTCTTATCGGTGAACCA
GGTGTCGGAAAAACGGCCGTTGTCGAAGGTCTAGCTCAGAAAATCGTTGATGGCGACGTTCCACATAAACTACAAGGCAA
ACAAGTCATCCGTCTGGATGTGGTTAGCCTAGTTCAAGGAACAGGTATCCGTGGACAATTTGAAGAACGCATGCAAAAAC
TCATGGAAGAAATTCGCAAACGTGAGGACATCATCCTCTTTATCGATGAAATCCATGAAATTGTTGGTGCTGGTTCTGCG
GGCGATGGCAATATGGATGCAGGAAATATCCTCAAGCCCGCTCTTGCCCGTGGGGAACTGCAACTGGTCGGTGCTACTAC
CCTCAATGAATACCGTATTATTGAAAAGGATGCTGCGCTAGAGCGCCGTATGCAGCCTGTCAAGGTCGATGAACCAACAG
TGGAAGAAACAATCACTATCCTCAAAGGAATTCAAAAGAAATACGAAGACTACCACCACGTTCAGTATACCGATGCTGCG
ATTGAAGCAGCTGCAACTCTTTCCAATCGCTACATCCAAGACCGCTTCTTGCCTGACAAGGCCATTGACCTCCTAGATGA
AGCTGGTTCTAAGATGAATTTGACCCTCAACTTTGTGGATCCTAAAGTCATTGATCAGCGCTTGATTGAGGCTGAAAATC
TTAAATCTCAAGCTACACGAGAGGAAGATTTTGAGAAGGCCGCCTACTTCCGCGACCAGATTGCCAAGTATAAGGAAATG
CAAAAGAAAAAGGTCACAGACCAAGATACTCCTATCATCAGTGAAAAAACCATTGAGCATATTATCGAGCAGAAAACCAA
TATCCCTGTTGGTGATTTAAAAGAGAAAGAACAATCTCAACTCATCCATCTAGCCGAAGATCTCAAGTCTCATGTTATTG
GCCAAGATGATGCAGTCGATAAGATTGCCAAGGCTATTCGCCGTAATCGTGTCGGTCTCGGTACCCCTAACCGTCCGATT
GGAAGCTTCCTCTTCGTTGGGCCAACTGGCGTCGGTAAGACCGAACTTTCCAAACAACTGGCCATCGAACTATTTGGTTC
TGCTGACAGTATGATTCGCTTCGATATGAGTGAATACATGGAAAAACACAGCGTGGCGAAATTAGTTGGTGCCCCTCCAG
GTTATGTTGGCTACGATGAGTCTGGGCAATTAACTGAAAAAGTTCGCCGCAATCCATATTCTCTTATTCTCTTGGATGAA
GTAGAGAAAGCCCATCCAGATGTTATGCACATGTTCCTCCAGGTCTTGGACGATGGTCGTTTGACAGACGGGCAAGGACG
TACCGTTAGCTTCAAGGATGCCATCATCATCATGACTTCAAATGCAGGTACTGGTAAAGCCGAAGCCAGCGTTGGATTTG
GTGCTGCTAGAGAAGGACGTACCAACTCTGTTCTCGGTGAACTCGGTAACTTCTTTAGCCCAGAGTTTATGAACCGTTTT
GATGGTATTATCGAATTTAAGGCTCTCAGCAAGGACAATCTCCTTCAGATTGTCGAGCTTATGCTAGCAGATGTTAACAA
ACGTCTTTCTAGCAACAACATTCATTTGGATGTAACTGACAAGGTCAAGGAAAAATTGGTTGACCTCGGCTATGATCCAA
AAATGGGAGCACGCCCACTTCGTCGTACTATTCAAGACTATATTGAGGACGCAATCACTGACTTCTACCTTGAAAATCCA
AGCGAAAAAGACCTCAAGGCAGTTATGACCAGCAAGGGCAACATTCAAATCAAATCTGCCAAAAAAGCTAAAGTAAAAAC
TTCTGAAAAAGAAGTATAA

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(649-723)

AAA domain (Cdc48 subfamily) (AAA_2)

(478-641)

ATPase family associated with various cellular activities (AAA) (AAA)

(155-274)

AAA lid domain (AAA_lid_9)

(293-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus pneumoniae Rx1

98.136

99.867

0.98
  clpE Streptococcus pneumoniae D39

98.136

99.867

0.98
  clpE Streptococcus pneumoniae R6

98.136

99.867

0.98
  clpE Streptococcus pneumoniae TIGR4

98.003

99.867

0.979
  clpE Streptococcus mutans UA159

83.2

99.734

0.83
  clpC Lactococcus lactis subsp. cremoris KW2

75.494

100

0.762
  clpC Bacillus subtilis subsp. subtilis str. 168

51.714

89.229

0.461
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

47.847

83.378

0.399
  clpC Streptococcus pneumoniae TIGR4

47.293

83.511

0.395
  clpC Streptococcus pneumoniae Rx1

46.91

83.91

0.394
  clpC Streptococcus pneumoniae D39

46.91

83.91

0.394
  clpC Streptococcus mutans UA159

46.89

83.378

0.391
  clpC Streptococcus thermophilus LMD-9

46.795

82.979

0.388
  clpC Streptococcus thermophilus LMG 18311

46.4

83.112

0.386

Multiple sequence alignment