Detailed information NTG1007283

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: ABLU27_RS03060
• Genome accession: NZ_CP157500
• Coordinates: 519023..520051 (-)
• Length: 342 a.a.
• NCBI ID: WP_003132657.1
• Uniprot ID: S6FVM6
• Organism: Lactococcus lactis strain 2B-9
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 514023..525051

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ABLU27_RS03030 (ABLU27_03030)	-	515098..515316 (-)	219	WP_406834868.1	hypothetical protein	-
ABLU27_RS03035 (ABLU27_03035)	-	515326..515955 (-)	630	WP_406834870.1	transcriptional regulator	-
ABLU27_RS03040 (ABLU27_03040)	-	516066..516407 (-)	342	WP_406834872.1	hypothetical protein	-
ABLU27_RS03045 (ABLU27_03045)	-	516716..517204 (-)	489	WP_406834874.1	MFS transporter	-
ABLU27_RS03050 (ABLU27_03050)	kwcM	517201..518520 (-)	1320	WP_058207975.1	KxxxW cyclic peptide radical SAM maturase	-
ABLU27_RS03055 (ABLU27_03055)	-	518588..518701 (-)	114	WP_011836076.1	KxxxW-cyclized peptide pheromone	-
ABLU27_RS03060 (ABLU27_03060)	sepM	519023..520051 (-)	1029	WP_003132657.1	SepM family pheromone-processing serine protease	Regulator
ABLU27_RS03065 (ABLU27_03065)	coaD	520038..520535 (-)	498	WP_010906348.1	pantetheine-phosphate adenylyltransferase	-
ABLU27_RS03070 (ABLU27_03070)	rsmD	520583..521122 (-)	540	WP_015427191.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
ABLU27_RS03075 (ABLU27_03075)	-	521293..522513 (-)	1221	WP_003132654.1	MFS transporter	-
ABLU27_RS03080 (ABLU27_03080)	lmrP	522596..523822 (-)	1227	WP_012898648.1	multidrug efflux MFS transporter LmrP	-
ABLU27_RS03085 (ABLU27_03085)	-	524010..524504 (+)	495	WP_017865181.1	RNA polymerase sigma factor	-

Sequence

Protein

• Length: 342 a.a.
• Molecular weight: 37349.96 Da
• Isoelectric Point: 9.9183

>NTDB_id=1007283 ABLU27_RS03060 WP_003132657.1 519023..520051(-) (sepM) [Lactococcus lactis strain 2B-9]
MKKNKKINPKLKWGISIGLIVVALLALFYPTSYYVEMPGTTEPLGKMVKVEGKKDEHKGDFFLTTVQIARANLATMIYSH
FNSFTSIYSEQEMTGGLNDAQFNRVNQFYMETAQNTAIYQAFKLANKPYELKYEGVYVLDIAKNSTFKNKLELADTITAV
NGQQFTSSADMIAYVSKQKVGDSVTIEYTRIDGTKHKSTGKYIKIANGKTGIGISLVDHTEVVTTPKVTVNAGSIGGPSA
GMMFTLEIYSQLTGKDLRNGREIAGTGTIEHDGSIGQIGGVDKKVATASKEGAKVFLVPDSGTKKESSNNYLGAKAAAKK
LKTKMKIVPVKTIQDALDYLEK

Nucleotide

• Length: 1029 bp

>NTDB_id=1007283 ABLU27_RS03060 WP_003132657.1 519023..520051(-) (sepM) [Lactococcus lactis strain 2B-9]
ATGAAAAAAAATAAAAAAATTAATCCCAAATTAAAATGGGGAATCTCGATTGGTCTAATTGTTGTTGCCCTTTTAGCTTT
ATTTTATCCAACGAGTTACTATGTGGAAATGCCCGGAACAACCGAGCCTTTAGGGAAAATGGTCAAAGTTGAAGGCAAAA
AAGATGAACATAAAGGTGATTTTTTCCTGACGACTGTCCAAATTGCACGAGCAAATCTTGCTACAATGATTTACAGCCAT
TTTAATAGTTTTACAAGCATTTATAGTGAGCAAGAAATGACTGGTGGACTTAACGACGCACAGTTCAACCGTGTCAACCA
GTTTTACATGGAAACGGCACAGAATACAGCGATTTATCAAGCTTTTAAATTAGCTAATAAACCTTATGAACTTAAATATG
AAGGCGTTTATGTCCTTGATATTGCCAAAAATTCGACCTTTAAAAATAAGCTAGAACTTGCAGATACGATTACAGCAGTC
AATGGTCAACAGTTTACATCAAGTGCCGACATGATTGCTTATGTTTCCAAACAAAAAGTCGGTGATTCAGTAACGATTGA
ATACACGAGAATTGACGGCACAAAGCACAAGTCAACTGGCAAATACATCAAAATTGCTAATGGAAAAACAGGAATTGGGA
TCAGCCTAGTTGACCATACTGAAGTCGTGACGACTCCAAAAGTTACTGTCAACGCGGGTTCAATCGGCGGTCCCTCTGCG
GGGATGATGTTTACACTAGAAATTTACAGTCAGTTGACAGGAAAAGATTTGCGAAACGGTCGCGAAATTGCTGGAACTGG
AACGATTGAACATGACGGAAGCATTGGCCAAATCGGCGGTGTTGATAAAAAAGTAGCCACAGCGAGCAAAGAAGGGGCAA
AGGTCTTCTTAGTGCCTGACTCAGGCACCAAAAAGGAAAGTAGCAACAATTACCTTGGAGCCAAAGCCGCAGCTAAAAAA
CTAAAAACGAAGATGAAAATCGTTCCCGTCAAAACTATTCAGGACGCTTTAGATTATTTAGAAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (134-194)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (227-338)

3D structure

• AlphaFold DB: S6FVM6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	48.696	100	0.491