Detailed information NTG1007195

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: GPW69_RS10180
• Genome accession: NZ_LR738724
• Coordinates: 2104581..2107121 (-)
• Length: 846 a.a.
• NCBI ID: WP_074391260.1
• Uniprot ID: -
• Organism: Streptococcus suis isolate 9401240
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2099581..2112121

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GPW69_RS10150	-	2100753..2101496 (-)	744	WP_013730659.1	amino acid ABC transporter ATP-binding protein	-
GPW69_RS10155	-	2101496..2102299 (-)	804	WP_074391256.1	amino acid ABC transporter permease	-
GPW69_RS10160	-	2102485..2103336 (-)	852	WP_024384261.1	amino acid ABC transporter substrate-binding protein	-
GPW69_RS10165	-	2103369..2104055 (-)	687	WP_074391257.1	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	-
GPW69_RS10170	-	2104169..2104342 (-)	174	WP_002941962.1	hypothetical protein	-
GPW69_RS10175	-	2104376..2104498 (-)	123	WP_074391259.1	DUF3021 family protein	-
GPW69_RS10180	hexA	2104581..2107121 (-)	2541	WP_074391260.1	DNA mismatch repair protein MutS	Machinery gene
GPW69_RS10185	argR	2107136..2107576 (-)	441	WP_002937036.1	arginine repressor	-
GPW69_RS10190	argS	2107683..2109371 (+)	1689	WP_074391261.1	arginine--tRNA ligase	-
GPW69_RS10195	-	2109551..2110465 (+)	915	WP_074391262.1	SH3 domain-containing protein	-
GPW69_RS10200	-	2110519..2111043 (-)	525	WP_024384267.1	membrane protein	-
GPW69_RS10205	-	2111155..2111337 (+)	183	WP_074391263.1	hypothetical protein	-

Sequence

Protein

• Length: 846 a.a.
• Molecular weight: 94990.69 Da
• Isoelectric Point: 5.0187

>NTDB_id=1007195 GPW69_RS10180 WP_074391260.1 2104581..2107121(-) (hexA) [Streptococcus suis isolate 9401240]
MAIEKISPGMQQYLDIKAQYPDAFLLFRMGDFYELFYEDAVEAAQILELSLTSRNKNAENPIPMAGVPYHAAQQYIDTLV
ELGHKVAIAEQMEDPKQAVGVVKREVVQVITPGTVTDSSKMGADSNYLVAIDRQGVQFALSYMDVSTGQFFVTSLDDFTS
LCGEIRNLRARELVIGYALSEEEEQVFSNQMNLLLSFEEEVTEDVQLIDNSLTDLEKAAAGKLLSYLHRTQMRDLSHLQK
VVHYEIKDYLQMDYATKSSLDLLENGRTGKKHGSLYWLLDETKTAMGMRLLRTWIDRPLIDLKRIENRQAVVQVFLDYFF
ERSDLVEALKGVYDIERLASRVSFGKTMPKDLLQLSQTLGNIPAIKNILLQINEPALGNLVAGLDPIPELHALISSAIAP
EAQGTITDGNIIRTGFDETLDQYRLVMREGAGWIAEIEAKEREASGINNLKIDYNKKDGYYFHVTNSNLGNVPSHFFRKA
TLKNSERYGTEELAKIEGQMLEARDKSANLEYEIFMRIRQEVEKYIGRLQKLARTIATIDVLQAFAVVAEQQHLVCPRFT
VQRELTIDRGRHAVVEKVMGKQTYIPNSIHLNTDTHMQLITGPNMSGKSTYMRQLAVIVILAQMGSYVPADQAALPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANKAVRLATDRSLILFDELGRGTATYDGMALAQSIIEYIHDKIGAKTLFATHYHEL
TDLSQTLEHLENVHVSTLEKDGQVTFLHKIAQGPADKSYGIHVAKIAGMPEELLQRADRILQTLENQAPTAPTHPAPSVV
EEPSGQIDLFADTPSHPVLDELAKLDIYNMTPMEVMMRVAELKKKL

Nucleotide

• Length: 2541 bp

>NTDB_id=1007195 GPW69_RS10180 WP_074391260.1 2104581..2107121(-) (hexA) [Streptococcus suis isolate 9401240]
ATGGCAATAGAAAAAATTTCTCCGGGAATGCAGCAGTATCTGGATATAAAAGCACAGTATCCAGATGCTTTTTTGCTTTT
CCGTATGGGAGACTTTTATGAGTTATTTTATGAAGATGCGGTAGAAGCGGCACAGATTTTGGAACTGTCCCTGACCAGTC
GGAATAAGAATGCGGAGAATCCGATTCCTATGGCGGGGGTACCGTATCACGCGGCACAACAGTATATCGACACACTTGTT
GAATTGGGGCATAAGGTCGCTATTGCTGAGCAGATGGAAGATCCTAAGCAGGCAGTCGGCGTGGTCAAGCGGGAAGTAGT
GCAGGTCATTACTCCTGGTACGGTAACAGATTCGTCCAAAATGGGAGCCGACAGTAACTATTTGGTTGCGATTGACCGTC
AGGGAGTGCAGTTCGCACTTTCTTATATGGATGTGTCAACAGGTCAGTTTTTTGTGACTAGTTTGGATGATTTTACCAGT
CTTTGCGGTGAAATCCGCAATTTACGGGCACGTGAATTGGTCATCGGCTATGCTCTGTCGGAGGAAGAGGAGCAGGTTTT
CTCGAATCAGATGAACTTGTTGCTGTCTTTTGAGGAGGAGGTGACGGAGGATGTTCAGCTGATTGACAACTCGCTGACGG
ATTTGGAAAAGGCTGCGGCTGGGAAACTCCTCAGCTACCTTCATCGGACTCAGATGCGAGATCTGAGCCACTTGCAAAAG
GTGGTCCATTATGAAATCAAGGACTATCTGCAAATGGACTATGCAACCAAGTCTAGCCTGGACCTGCTTGAAAACGGTCG
GACAGGTAAGAAGCATGGTAGTTTGTACTGGTTGTTAGACGAAACCAAGACAGCCATGGGTATGCGACTATTACGGACAT
GGATTGATCGTCCCTTGATTGACCTTAAGCGGATTGAGAATCGTCAGGCTGTCGTTCAGGTTTTTCTGGATTACTTCTTT
GAACGGAGTGACTTGGTCGAGGCTTTAAAAGGTGTCTATGACATCGAACGCTTGGCCAGTCGGGTGTCTTTTGGAAAAAC
CATGCCCAAGGATCTCTTGCAGCTCTCCCAGACTCTGGGAAATATCCCAGCAATCAAGAATATCTTGCTACAAATCAATG
AGCCTGCTCTAGGCAATCTGGTAGCTGGATTGGACCCAATTCCAGAACTGCATGCTCTCATCAGCTCTGCTATTGCCCCA
GAAGCCCAAGGGACCATCACAGATGGAAATATCATCCGTACGGGCTTTGACGAAACGCTGGATCAGTACCGTCTGGTCAT
GCGTGAGGGAGCGGGTTGGATTGCGGAGATTGAGGCCAAGGAGCGTGAAGCGTCTGGTATCAACAATCTTAAGATTGATT
ACAATAAAAAAGACGGTTACTATTTTCATGTGACCAATTCCAATCTGGGCAATGTGCCTAGTCATTTCTTCCGTAAGGCG
ACCTTGAAAAACTCGGAGCGCTATGGAACGGAAGAGTTGGCTAAGATCGAAGGGCAGATGTTGGAGGCGCGTGATAAGTC
TGCTAATTTGGAGTACGAGATTTTCATGCGGATTCGCCAAGAGGTTGAGAAGTATATCGGTCGCTTGCAGAAGTTGGCTC
GGACCATTGCAACCATCGATGTTTTGCAGGCTTTTGCAGTTGTGGCAGAGCAGCAACATTTGGTTTGTCCACGCTTTACA
GTTCAAAGAGAACTAACCATTGACCGTGGACGTCATGCAGTGGTGGAGAAGGTCATGGGCAAGCAGACCTATATTCCCAA
CTCTATTCACTTGAATACCGATACGCATATGCAACTGATTACTGGTCCAAACATGAGTGGTAAGTCTACCTATATGCGGC
AGTTGGCGGTTATTGTCATTCTGGCGCAGATGGGTTCTTATGTGCCTGCGGATCAGGCTGCATTGCCGATTTTCGATGCT
ATTTTCACTCGGATTGGGGCGGCAGACGACTTGGTCAGCGGTCAGTCTACCTTTATGGTCGAGATGATGGAGGCCAATAA
GGCGGTCCGTCTGGCGACAGATCGGTCGCTCATCCTCTTTGACGAACTTGGACGGGGAACGGCCACCTATGACGGTATGG
CCCTGGCCCAGTCTATCATCGAGTACATCCACGACAAGATTGGTGCCAAGACTCTCTTTGCCACCCACTACCATGAGTTG
ACAGACCTTAGCCAGACCTTAGAACACCTAGAGAATGTCCATGTATCGACCTTGGAGAAGGACGGCCAAGTCACCTTCCT
CCACAAGATTGCCCAAGGTCCAGCTGACAAGTCCTACGGGATCCATGTGGCTAAGATTGCGGGAATGCCAGAGGAGCTAT
TGCAGCGGGCGGATAGGATTTTGCAGACGCTTGAAAACCAAGCCCCTACTGCACCAACTCACCCAGCTCCGTCAGTTGTG
GAAGAGCCGTCTGGTCAAATCGACCTCTTCGCAGACACGCCATCTCACCCAGTCCTCGATGAACTGGCAAAACTGGACAT
CTATAATATGACCCCAATGGAAGTCATGATGAGGGTGGCAGAATTGAAGAAGAAACTATAA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (599-785)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain II (MutS_II) (126-239)

• MutS domain I (MutS_I) (8-118)

• MutS domain III (MutS_III) (256-546)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	74.232	100	0.742
mutS	Pseudomonas stutzeri strain ATCC 17587	37.529	100	0.381